EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION
Yıl: 2021 Cilt: 32 Sayı: 4 Sayfa Aralığı: 139 - 143 Metin Dili: İngilizce DOI: 10.4274/jtss.galenos.2021.66376 İndeks Tarihi: 15-01-2022
EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION
Öz: Objective: Lumbar disc herniation (LDH) is a socio-economic burden. The physiopathology of the disease is not clarified completely. This study aimed to investigate the oxidation-reduction balance in LDH via serum thiol-disulfide and ischemia-modified albumin (IMA) levels. Materials and Methods: This prospective case-control study included 30 patients with LDH and a control group with 30 healthy volunteers. Blood samples were analyzed for total thiol (-SH+ -S-S-), native thiol (-SH), and IMA levels. Disulfide levels and native thiol/total thiol ratio were calculated. The results of the two groups were compared. Results: Native and total thiol levels were significantly higher in the LDH group than in the control group (p=0.007 and p=0.008, respectively). IMA levels were significantly higher in the LDH group than in the control group (p=0.000). The receiver operating characteristic curve demonstrated that the IMA value of 1.41 could predict the LDH with 80% sensitivity and 80% specificity (area under curve=0.888, confidence interval: 0.802- 0.974). Conclusion: LDH influences the thiol-disulfide balance, and increased IMA levels can predict LDH.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA | öcal ö, SEÇEN A, Divanlioglu D, Dağlar Z, GÜNERHAN G, Fırat Oğuz E, EREL O, DALGIC A (2021). EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. , 139 - 143. 10.4274/jtss.galenos.2021.66376 |
Chicago | öcal özgür,SEÇEN AHMET EREN,Divanlioglu Denizhan,Dağlar Zeynep,GÜNERHAN GÖKSAL,Fırat Oğuz Esra,EREL Ozcan,DALGIC Ali EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. (2021): 139 - 143. 10.4274/jtss.galenos.2021.66376 |
MLA | öcal özgür,SEÇEN AHMET EREN,Divanlioglu Denizhan,Dağlar Zeynep,GÜNERHAN GÖKSAL,Fırat Oğuz Esra,EREL Ozcan,DALGIC Ali EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. , 2021, ss.139 - 143. 10.4274/jtss.galenos.2021.66376 |
AMA | öcal ö,SEÇEN A,Divanlioglu D,Dağlar Z,GÜNERHAN G,Fırat Oğuz E,EREL O,DALGIC A EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. . 2021; 139 - 143. 10.4274/jtss.galenos.2021.66376 |
Vancouver | öcal ö,SEÇEN A,Divanlioglu D,Dağlar Z,GÜNERHAN G,Fırat Oğuz E,EREL O,DALGIC A EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. . 2021; 139 - 143. 10.4274/jtss.galenos.2021.66376 |
IEEE | öcal ö,SEÇEN A,Divanlioglu D,Dağlar Z,GÜNERHAN G,Fırat Oğuz E,EREL O,DALGIC A "EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION." , ss.139 - 143, 2021. 10.4274/jtss.galenos.2021.66376 |
ISNAD | öcal, özgür vd. "EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION". (2021), 139-143. https://doi.org/10.4274/jtss.galenos.2021.66376 |
APA | öcal ö, SEÇEN A, Divanlioglu D, Dağlar Z, GÜNERHAN G, Fırat Oğuz E, EREL O, DALGIC A (2021). EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. Journal of Turkish Spinal Surgery, 32(4), 139 - 143. 10.4274/jtss.galenos.2021.66376 |
Chicago | öcal özgür,SEÇEN AHMET EREN,Divanlioglu Denizhan,Dağlar Zeynep,GÜNERHAN GÖKSAL,Fırat Oğuz Esra,EREL Ozcan,DALGIC Ali EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. Journal of Turkish Spinal Surgery 32, no.4 (2021): 139 - 143. 10.4274/jtss.galenos.2021.66376 |
MLA | öcal özgür,SEÇEN AHMET EREN,Divanlioglu Denizhan,Dağlar Zeynep,GÜNERHAN GÖKSAL,Fırat Oğuz Esra,EREL Ozcan,DALGIC Ali EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. Journal of Turkish Spinal Surgery, vol.32, no.4, 2021, ss.139 - 143. 10.4274/jtss.galenos.2021.66376 |
AMA | öcal ö,SEÇEN A,Divanlioglu D,Dağlar Z,GÜNERHAN G,Fırat Oğuz E,EREL O,DALGIC A EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. Journal of Turkish Spinal Surgery. 2021; 32(4): 139 - 143. 10.4274/jtss.galenos.2021.66376 |
Vancouver | öcal ö,SEÇEN A,Divanlioglu D,Dağlar Z,GÜNERHAN G,Fırat Oğuz E,EREL O,DALGIC A EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION. Journal of Turkish Spinal Surgery. 2021; 32(4): 139 - 143. 10.4274/jtss.galenos.2021.66376 |
IEEE | öcal ö,SEÇEN A,Divanlioglu D,Dağlar Z,GÜNERHAN G,Fırat Oğuz E,EREL O,DALGIC A "EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION." Journal of Turkish Spinal Surgery, 32, ss.139 - 143, 2021. 10.4274/jtss.galenos.2021.66376 |
ISNAD | öcal, özgür vd. "EVALUATION OF SERUM THIOL/DISULFIDE HOMEOSTASIS AND ISCHEMIA-MODIFIED ALBUMIN LEVELS IN LUMBAR DISC HERNIATION". Journal of Turkish Spinal Surgery 32/4 (2021), 139-143. https://doi.org/10.4274/jtss.galenos.2021.66376 |