Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT
Yıl: 2021 Cilt: 30 Sayı: 2 Sayfa Aralığı: 126 - 128 Metin Dili: İngilizce İndeks Tarihi: 16-01-2022
Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT
Öz: A 34-year-old male patient who had left orchiectomy and received three cycles of chemotherapy for testicular mix germ cell carcinoma was referred for 18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for complaints of weight loss and fever. PET/CT showed multiple and progressive 18F-FDG uptakes in supra and infra diaphragmatic lymphatic regions, and multiple abnormal 18F-FDG uptakes were noted in the lytic formed skeletal lesions. Clinicians remain in doubt regarding the multiple metastatic lesions without elevated serum tumor marker levels (alpha-fetoprotein, beta-human chorionic gonadotrophin, CA19-9, and carcinoembryonic antigen). Biopsy of the lytic lesion in the iliac bone revealed granulomatous inflammation suggestive of sarcoidosis. Systemic prednisone at 20-40 mg/daily was started. 18F-FDG PET/CT images showed complete metabolic response to prednisone 8 months following the start of treatment.
Anahtar Kelime: 18F-FDG PET/BT Görüntülemede Metastatik Testis Karsinomunu Taklit Eden Kemoterapi Tedavisinin İndüklediği Sistemik Sarkoidoz
Öz: Orşiektomi yapılan ve testis mikst germ hücreli karsinomu tanısı nedeni ile 3 kür kemoterapi alan 34 yaşındaki erkek hastada, kilo kaybı şikayeti nedeniyle nüks hastalık şüphesi ile 18flor-florodeoksiglukoz (18F-FDG) pozitron emisyon tomografi/bilgisayarlı tomografi (PET/BT) görüntülemesi yapıldı. PET/BT’de supra ve infra diyafragmatik lenfatik istasyonlarda çok sayıda ve patolojik FDG tutulumu gözlendi. Ayrıca litik görünümlü çok sayıda iskelet lezyonlarında da anormal 18F-FDG tutulumu kaydedildi. Klinisyen, serum tümör belirteç (alfa feto protein, beta insan koryonik gonadotropin, CA19-9 ve karsinoembriyonik antijen) düzeyi yükselmemiş metastatik multipl lezyonlar konusunda şüphelenerek olguya iliak kemikteki litik lezyondan biyopsi incelemesi önerdi. Histopatolojik sonuç sarkoidoz düşündüren granülomatöz inflamasyon gösteren odak olarak raporlanması üzerine günlük 20-40 mg/gün sistemik prednizon başlandı. Sistemik prednizon tedavisine başlandıktan 8 ay sonraki 18F-FDG PET/BT görüntüleri tam metabolik yanıt göstermektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Diğer Erişim Türü: Erişime Açık
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| APA | ARSLAN E, Aksoy T, Ekemen S, Cermik T (2021). Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. , 126 - 128. |
| Chicago | ARSLAN ESRA,Aksoy Tamer,Ekemen Suheyla,Cermik Tevfik Fikret Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. (2021): 126 - 128. |
| MLA | ARSLAN ESRA,Aksoy Tamer,Ekemen Suheyla,Cermik Tevfik Fikret Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. , 2021, ss.126 - 128. |
| AMA | ARSLAN E,Aksoy T,Ekemen S,Cermik T Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. . 2021; 126 - 128. |
| Vancouver | ARSLAN E,Aksoy T,Ekemen S,Cermik T Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. . 2021; 126 - 128. |
| IEEE | ARSLAN E,Aksoy T,Ekemen S,Cermik T "Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT." , ss.126 - 128, 2021. |
| ISNAD | ARSLAN, ESRA vd. "Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT". (2021), 126-128. |
| APA | ARSLAN E, Aksoy T, Ekemen S, Cermik T (2021). Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. Molecular Imaging and Radionuclide Therapy, 30(2), 126 - 128. |
| Chicago | ARSLAN ESRA,Aksoy Tamer,Ekemen Suheyla,Cermik Tevfik Fikret Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. Molecular Imaging and Radionuclide Therapy 30, no.2 (2021): 126 - 128. |
| MLA | ARSLAN ESRA,Aksoy Tamer,Ekemen Suheyla,Cermik Tevfik Fikret Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. Molecular Imaging and Radionuclide Therapy, vol.30, no.2, 2021, ss.126 - 128. |
| AMA | ARSLAN E,Aksoy T,Ekemen S,Cermik T Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. Molecular Imaging and Radionuclide Therapy. 2021; 30(2): 126 - 128. |
| Vancouver | ARSLAN E,Aksoy T,Ekemen S,Cermik T Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT. Molecular Imaging and Radionuclide Therapy. 2021; 30(2): 126 - 128. |
| IEEE | ARSLAN E,Aksoy T,Ekemen S,Cermik T "Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT." Molecular Imaging and Radionuclide Therapy, 30, ss.126 - 128, 2021. |
| ISNAD | ARSLAN, ESRA vd. "Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT". Molecular Imaging and Radionuclide Therapy 30/2 (2021), 126-128. |
