Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study

Mutlu, İlknur; CEVHER AKDULUM, M. Funda; KARAKAYA, Cengiz; Erdem, Mehmet; ERDEM, AHMET; Demirdag, Erhan

doi:10.3906/sag-2012-149

Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study

İlknur SELVİ, (Koru Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, Ankara, Türkiye)

Mehmet ERDEM, (Gazi Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Ankara, Türkiye)

Erhan DEMİRDAĞ, (Gazi Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Ankara, Türkiye)

Funda CEVHER AKDULUM, (Gazi Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Ankara, Türkiye)

Cengiz KARAKAYA, (Gazi Üniversitesi, Tıp Fakültesi, Tıbbi Biyokimya ve Tüp Bebek Ünitesi Anabilim Dalı, Ankara, Türkiye)

Ahmet ERDEM (Gazi Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Ankara, Türkiye)

Turkish Journal of Medical Sciences

1 0

Yıl: 2021 Cilt: 51 Sayı: 3 Sayfa Aralığı: 1365 - 1372 Metin Dili: İngilizce DOI: 10.3906/sag-2012-149 İndeks Tarihi: 19-01-2022

Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study

Öz:

Background/aim: To investigate the optimal protocol for frozen-thawed embryo transfer (FET) cycles in patients who previously had a cycle cancellation due to uterine peristalsis (UP). Materials and methods: Thirty-four patients with previous embryo transfer (ET) cancellation due to UP during artificial cycle (AC) were included retrospectively. In the proceeding cycle, endometrium was prepared with AC (n: 23) in AC-FET group or with stimulated cycle that contains letrozole (L) (n: 11) in L-FET group. Intravenous bolus dose of 6.75 mg atosiban (Tractocile; Ferring Pharmaceuticals, Switzerland) injection was performed to all patients of AC-FET group due to UP ≥ 4/min on the planned ET day of proceeding cycle. Atosiban was not used in L-FET group. Primary outcome was live birth rate (LBR) per ET. Secondary outcomes were clinical pregnancy rate (CPR) per ET, implantation rate (IR), cycle cancellation rate. Results: The baseline characteristics such as age, body mass index, antral follicle count, duration of infertility, and the number of prior in vitro fertilization attempts of each group were similar. The IR, CPR per ET, LBR per ET, CPR per cycle and LBR per cycle were significantly higher; cycle cancellation rates were significantly lower in L-FET group as compared to the AC-FET group. Conclusion: Endometrial preparation with letrozole significantly improves CPR and LBR in FET cycles of patients with previous cycle cancellations due to UP.Key words: Uterine peristalsis, frozen-thawed cycle, embryo transfer, letrozole, atosiban

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Mutlu İ, Erdem M, Demirdag E, CEVHER AKDULUM M, KARAKAYA C, ERDEM A (2021). Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. , 1365 - 1372. 10.3906/sag-2012-149
Chicago	Mutlu İlknur,Erdem Mehmet,Demirdag Erhan,CEVHER AKDULUM M. Funda,KARAKAYA Cengiz,ERDEM AHMET Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. (2021): 1365 - 1372. 10.3906/sag-2012-149
MLA	Mutlu İlknur,Erdem Mehmet,Demirdag Erhan,CEVHER AKDULUM M. Funda,KARAKAYA Cengiz,ERDEM AHMET Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. , 2021, ss.1365 - 1372. 10.3906/sag-2012-149
AMA	Mutlu İ,Erdem M,Demirdag E,CEVHER AKDULUM M,KARAKAYA C,ERDEM A Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. . 2021; 1365 - 1372. 10.3906/sag-2012-149
Vancouver	Mutlu İ,Erdem M,Demirdag E,CEVHER AKDULUM M,KARAKAYA C,ERDEM A Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. . 2021; 1365 - 1372. 10.3906/sag-2012-149
IEEE	Mutlu İ,Erdem M,Demirdag E,CEVHER AKDULUM M,KARAKAYA C,ERDEM A "Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study." , ss.1365 - 1372, 2021. 10.3906/sag-2012-149
ISNAD	Mutlu, İlknur vd. "Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study". (2021), 1365-1372. https://doi.org/10.3906/sag-2012-149

APA	Mutlu İ, Erdem M, Demirdag E, CEVHER AKDULUM M, KARAKAYA C, ERDEM A (2021). Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. Turkish Journal of Medical Sciences, 51(3), 1365 - 1372. 10.3906/sag-2012-149
Chicago	Mutlu İlknur,Erdem Mehmet,Demirdag Erhan,CEVHER AKDULUM M. Funda,KARAKAYA Cengiz,ERDEM AHMET Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. Turkish Journal of Medical Sciences 51, no.3 (2021): 1365 - 1372. 10.3906/sag-2012-149
MLA	Mutlu İlknur,Erdem Mehmet,Demirdag Erhan,CEVHER AKDULUM M. Funda,KARAKAYA Cengiz,ERDEM AHMET Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. Turkish Journal of Medical Sciences, vol.51, no.3, 2021, ss.1365 - 1372. 10.3906/sag-2012-149
AMA	Mutlu İ,Erdem M,Demirdag E,CEVHER AKDULUM M,KARAKAYA C,ERDEM A Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. Turkish Journal of Medical Sciences. 2021; 51(3): 1365 - 1372. 10.3906/sag-2012-149
Vancouver	Mutlu İ,Erdem M,Demirdag E,CEVHER AKDULUM M,KARAKAYA C,ERDEM A Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study. Turkish Journal of Medical Sciences. 2021; 51(3): 1365 - 1372. 10.3906/sag-2012-149
IEEE	Mutlu İ,Erdem M,Demirdag E,CEVHER AKDULUM M,KARAKAYA C,ERDEM A "Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study." Turkish Journal of Medical Sciences, 51, ss.1365 - 1372, 2021. 10.3906/sag-2012-149
ISNAD	Mutlu, İlknur vd. "Comparison of frozen-thawed embryo transfer protocols in patients with previous cycle cancellation due to uterine peristalsis: a pilot study". Turkish Journal of Medical Sciences 51/3 (2021), 1365-1372. https://doi.org/10.3906/sag-2012-149