The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers

sert, Umit yasemin; Uzunlar, Ozlem; Çandar, Tuba; Kadıoğlu, Nezaket; ÜSTÜN, Yaprak ENGİN

doi::10.3906/sag-2009-181

The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers

Özlem UZUNLAR, (Sağlık Bilimleri Üniversitesi, Ankara Şehir Hastanesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Ankara, Türkiye)

Ümit Yasemin SERT, (Sağlık Bilimleri Üniversitesi, Ankara Şehir Hastanesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Ankara, Türkiye)

Nezaket KADIOĞLU, (Liv Hospital, Kadın Hastalıkları ve Doğum Kliniği, Ankara, Türkiye)

Tuba ÇANDAR, (Ufuk Üniversitesi, Biyokimya Bölümü, Ankara, Türkiye)

Yaprak ENGİN ÜSTÜN (Sağlık Bilimleri Üniversitesi, Etlik Zubeyde Hanım Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Ankara, Türkiye)

Turkish Journal of Medical Sciences

2 0

Yıl: 2021 Cilt: 51 Sayı: 3 Sayfa Aralığı: 1420 - 1427 Metin Dili: İngilizce DOI: :10.3906/sag-2009-181 İndeks Tarihi: 19-01-2022

The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers

Öz:

Background/aim: Water immersion and epidural analgesia are the most preferred pain relief methods during the labor process. Adverse effects related to these methods, impact on the labor, and perception of pain is well studied in the literature. We aimed to investigate the cord blood level of copeptin, total serum oxidant (TOS), antioxidant (TAS), interleukin (IL)-1, IL-6, and oxytocin after the labor with water immersion, epidural analgesia, and vaginal birth without pain relief. Materials and methods: The study was conducted with 102 healthy pregnant women admitted to the obstetric delivery unit for noncomplicated term birth. Copeptin, oxytocin, TAS, TOS, IL-1, and IL-6 levels of cord blood and obstetric and neonatal results after vaginal birth were compared. Results: The study included a total of 102 patients (group 1 = 30, group 2 = 30, and group 3 = 42). We found no significant difference between the three groups in terms of BMI, age, gravidity, parity, birth week, birth weight, interventional birth, perineal trauma, breastfeeding, duration of labor, oxytocin, IL-1 and IL-6 levels (p > 0.05). Neonatal intensive care unit (NICU) need, TAS, TOS, and copeptin levels were higher. Apgar scores were lower in the epidural group (p = 0.011, p = 0.036, p = 0.027, p < 0.001, and p < 0.001 respectively). Conclusion: Epidural analgesia has deteriorated oxidative stress status and lower neonatal Apgar scores with higher NICU administration compared with water birth and vaginal birth without pain relief.Key words: Epidural analgesia, infection, neuroendocrine, oxidative stress, waterbirth

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Uzunlar O, sert U, Kadıoğlu N, Çandar T, ÜSTÜN Y (2021). The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. , 1420 - 1427. :10.3906/sag-2009-181
Chicago	Uzunlar Ozlem,sert Umit yasemin,Kadıoğlu Nezaket,Çandar Tuba,ÜSTÜN Yaprak ENGİN The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. (2021): 1420 - 1427. :10.3906/sag-2009-181
MLA	Uzunlar Ozlem,sert Umit yasemin,Kadıoğlu Nezaket,Çandar Tuba,ÜSTÜN Yaprak ENGİN The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. , 2021, ss.1420 - 1427. :10.3906/sag-2009-181
AMA	Uzunlar O,sert U,Kadıoğlu N,Çandar T,ÜSTÜN Y The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. . 2021; 1420 - 1427. :10.3906/sag-2009-181
Vancouver	Uzunlar O,sert U,Kadıoğlu N,Çandar T,ÜSTÜN Y The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. . 2021; 1420 - 1427. :10.3906/sag-2009-181
IEEE	Uzunlar O,sert U,Kadıoğlu N,Çandar T,ÜSTÜN Y "The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers." , ss.1420 - 1427, 2021. :10.3906/sag-2009-181
ISNAD	Uzunlar, Ozlem vd. "The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers". (2021), 1420-1427. https://doi.org/:10.3906/sag-2009-181

APA	Uzunlar O, sert U, Kadıoğlu N, Çandar T, ÜSTÜN Y (2021). The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. Turkish Journal of Medical Sciences, 51(3), 1420 - 1427. :10.3906/sag-2009-181
Chicago	Uzunlar Ozlem,sert Umit yasemin,Kadıoğlu Nezaket,Çandar Tuba,ÜSTÜN Yaprak ENGİN The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. Turkish Journal of Medical Sciences 51, no.3 (2021): 1420 - 1427. :10.3906/sag-2009-181
MLA	Uzunlar Ozlem,sert Umit yasemin,Kadıoğlu Nezaket,Çandar Tuba,ÜSTÜN Yaprak ENGİN The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. Turkish Journal of Medical Sciences, vol.51, no.3, 2021, ss.1420 - 1427. :10.3906/sag-2009-181
AMA	Uzunlar O,sert U,Kadıoğlu N,Çandar T,ÜSTÜN Y The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. Turkish Journal of Medical Sciences. 2021; 51(3): 1420 - 1427. :10.3906/sag-2009-181
Vancouver	Uzunlar O,sert U,Kadıoğlu N,Çandar T,ÜSTÜN Y The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers. Turkish Journal of Medical Sciences. 2021; 51(3): 1420 - 1427. :10.3906/sag-2009-181
IEEE	Uzunlar O,sert U,Kadıoğlu N,Çandar T,ÜSTÜN Y "The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers." Turkish Journal of Medical Sciences, 51, ss.1420 - 1427, 2021. :10.3906/sag-2009-181
ISNAD	Uzunlar, Ozlem vd. "The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers". Turkish Journal of Medical Sciences 51/3 (2021), 1420-1427. https://doi.org/:10.3906/sag-2009-181