Yıl: 2021 Cilt: 11 Sayı: 1 Sayfa Aralığı: 9 - 14 Metin Dili: İngilizce DOI: 10.5222/buchd.2021.54366 İndeks Tarihi: 16-02-2022

Our Clinical Experiences in Patients with ID Nutcracker Syndrome

Öz:
Objective: Nutcracker syndrome (NCS) is a rare condition caused by the compression of the left renal vein between the abdominal aorta and superior mesenteric artery. The purpose of the study was to evaluate our management of NCS. Methods: Patients were retrospectively reviewed and sex, age, main symptoms at application, physical examination, radiological findings, laboratory examinations, and treatment were recorded. Results: 23 patients (16 girls, 7 boys; age range, 5 to 16) diagnosed with NCS. Microhematuria was detected with 14 (60.8%) patients before diagnosis. And four of 9 (39.1%) were determined after diagnosis. Microhematuria was not detected in 5 (21.7%) of the patients. All patients (100%) had orthostatic proteinuria. 17 (73.9%) patients had mild, 3 (13.0%) patients had moderate and 3 (13.0%) had severe proteinuria. The mean diameter of the left renal vein (LRV) at the aortomesenteric (AM) portions and the hilar were 1.69mm±0.70 and 8.01mm±2.27. The mean angle between the superior mesenteric artery and LRV was 25.26º±7.98. Conclusion: In the case of especially colic flank pain, hematuria, and proteinuria NCS should keep in mind in the differential diagnosis. Surgical management may supply more enough clinic improvement when the patient has a response to medical therapy.
Anahtar Kelime:

Nutcracker Sendromlu Hastalarda Klinik Deneyimlerimiz

Öz:
Amaç: Nutcracker sendromu (NCS), abdominal aorto ve superiar mezenterik arter arasındaki sol renal venin sıkışmasından kaynaklanan nadir bir durumdur. Çalışmanın amacı, NCS tanısı konulan hastalara genel yaklaşımımızı değerlendirmektir. Yöntem: Hastalar retrospektif olarak incelendi ve cinsiyet, yaş, uygulamadaki ana semptomlar, fizik muayene, radyolojik bulgular, laboratuvar muayeneleri ve tedavi kaydedildi. Bulgular: 23 hasta (16 kız, 7 erkek; yaş aralığı, 5-16) NKS tanısı aldı. Tanıdan önce 14 hastada (%60,8) mikrohematüri saptandı. Teşhisten 9 taneden dördünde (%39,1) tanı aldıktan sonra belirlendi. Hastaların 5’inde (%21,7) mikrohematüri saptanmadı. Tüm hastalarda (%100) ortostatik proteinüri vardı. 17 (%73,9) hastada hafif, 3 (%13,0) hastada orta, 3 (%13,0) hastada ciddi proteinüri vardı. Aortmezenterik (AM) ve hilerde sol renal venin (LRV) ortalama çapı 1.69mm±0,70 ve 8,01mm±2,27 idi. Üst mezenterik arter ve LRV arasındaki ortalama açı 25,26±7,98 idi. Sonuç: Özellikle kolik yan ağrısı, hematüri ve proteinüri olması durumunda NCS ayırıcı tanıda akılda tutulmalıdır. Cerrahi tedavi, hasta tıbbi tedaviye yanıt verdiğinde daha fazla klinik iyileşme sağlayabilir
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Ahmed K, Sampath R, Khan MS. Current trends in the diagnosis and management of renal nutcracker syndrome: A Review. Eur J Vasc Endovasc Surg. 2006;31(4):410-6. https://doi.org/10.1016/j.ejvs.2005.05.045
  • 2. Reed NR, Karla M, Bower TC, Vrtiska TJ, Ricotta II JJ, Gloviczki P. Left renal vein transposition for nutcracker syndrome. J Vasc Surg. 2009;49(2):386-94. https://doi.org/10.1016/j.jvs.2008.09.051
  • 3. Nickavar A. Nutcracker syndrome; a rare cause of hematuria. J Nephropathol. 2016;5(4):144-5. https://doi.org/10.15171/jnp.2016.27
  • 4. Brant W. Ullery, Nathan K. Itoga, Matthew W. Mell, Stanford. Transposition of the left renal vein for the treatment of nutcracker syndrome in children: A short-term experience. Annals of Vascular Surgery. 2014;28(8):1938.e5-8. https://doi.org/10.1016/j.avsg.2014.07.022
  • 5. Barbey F, Venetz JP, Calderari B, Nguyen QV, Meuwly JY. Orthostatic proteinuria and compression of the left renal vein (nutcracker syndrome). Presse Med. 2003;32(19):883-5.
  • 6. Waseem M, Upadhyay R, Prosper G. The nutcracker syndrome: an underrecognized cause of hematuria. Eur J Pediatr. 2012;(8):1269-71. https://doi.org/10.1007/s00431-012-1761-1
  • 7. Gorospe EC, Aigbe MO. Nutcracker syndrome: A rare cause of hematuria. Clinical Image The ScientificWorld Journal. 2006;30(6):745-6. https://doi.org/10.1100/tsw.2006.144
  • 8. Hanna HE, Santella RN, Zawada ET Jr, Masterson TE. Nutcracker syndrome: an underdiagnosed cause for hematuria? South Dakota Journal of Medicine. 1997;50(12):429-36.
  • 9. Barnes RW, Fleisher iii HL, Redman JF, Smith JW, Harshfield DL, Ferris EJ. Mesoaortic compression of the left renal vein (the so called nutcracker syndrome): Repair by a new stenting procedure. J Vasc Surg. 1988;8(4):415-21. https://doi.org/10.1016/0741-5214(88)90104-8
  • 10. Nalcacioglu H, Bilgici MC, Tekcan D, Genc G, Bostanci Y, Yakupoglu YK, Sarikaya S, Ozkaya O. Nutcracker Syndrome in Children: Role of Doppler Ultrasonographic Indices in Detecting the Pattern of Symptoms. Journal of Clinical Medicine. 2018;7:214. https://doi.org/10.3390/jcm7080214
  • 11. Denchev B, Domuschieva E, Jelev G, Govedarski V, Zahariev T. Surgical Treatment of a Patient With Nutcracker Syndrome via Transposition of the Left Renal Vein. EJVES Short Reports. 2018;41:10e12. https://doi.org/10.1016/j.ejvssr.2018.09.003
  • 12. Gulleroglu K, Gulleroglu B, Esra Baskin. Nutcracker syndrome. World J Nephrol. 2014;6;3(4):277-81. https://doi.org/10.5527/wjn.v3.i4.277
  • 13. Ma Z, Liu X, Ning Y. Nutcracker phenomenon in combination with glomerular nephritis in isolated hematuria patients. Int Urol Nephrol. 2013;45:809-16. https://doi.org/10.1007/s11255-012-0265-2
  • 14. Alaygut D, Bayram M, Soylu A, Cakmakcı H, Türkmen M, Kavukcu S. Clinical course of children with nutcracker syndrome. Urology. 2013;82(3):686-90. https://doi.org/10.1016/j.urology.2013.03.048
  • 15. Shaha D, Qiub X, Shahb A, Cao D. Posterior nutcracker syndrome with left renal vein duplication: Anuncommon cause of hematuria. International Journal of Surgery Case Reports. 2013;4:1142-4. https://doi.org/10.1016/j.ijscr.2013.10.012
  • 16. Ananthan K, Onida S, Davies AH. Nutcracker Syndrome: An Update on Current Diagnostic Criteria and Management Guidelines. Eur J Vasc Endovasc Surg. 2017;53(6):886-94. https://doi.org/10.1016/j.ejvs.2017.02.015
  • 17. Erben Y, Gloviczki P, Kalra M, Bjarnason H, Reed NR, Duncan AA, Oderich GS, Bower TC. Treatment of nutcracker syndrome with open and endovascular interventions. J Vasc Surg Venous Lymphat Disord. 2015;3(4):389-96. https://doi.org/10.1016/j.jvsv.2015.04.003
APA Yalçın Cömert H, Tural S, Şalcı G, Sarıhan H, İMAMOĞLU M (2021). Our Clinical Experiences in Patients with ID Nutcracker Syndrome. , 9 - 14. 10.5222/buchd.2021.54366
Chicago Yalçın Cömert Hatice Sonay,Tural Sema,Şalcı Gül,Sarıhan Haluk,İMAMOĞLU MUSTAFA Our Clinical Experiences in Patients with ID Nutcracker Syndrome. (2021): 9 - 14. 10.5222/buchd.2021.54366
MLA Yalçın Cömert Hatice Sonay,Tural Sema,Şalcı Gül,Sarıhan Haluk,İMAMOĞLU MUSTAFA Our Clinical Experiences in Patients with ID Nutcracker Syndrome. , 2021, ss.9 - 14. 10.5222/buchd.2021.54366
AMA Yalçın Cömert H,Tural S,Şalcı G,Sarıhan H,İMAMOĞLU M Our Clinical Experiences in Patients with ID Nutcracker Syndrome. . 2021; 9 - 14. 10.5222/buchd.2021.54366
Vancouver Yalçın Cömert H,Tural S,Şalcı G,Sarıhan H,İMAMOĞLU M Our Clinical Experiences in Patients with ID Nutcracker Syndrome. . 2021; 9 - 14. 10.5222/buchd.2021.54366
IEEE Yalçın Cömert H,Tural S,Şalcı G,Sarıhan H,İMAMOĞLU M "Our Clinical Experiences in Patients with ID Nutcracker Syndrome." , ss.9 - 14, 2021. 10.5222/buchd.2021.54366
ISNAD Yalçın Cömert, Hatice Sonay vd. "Our Clinical Experiences in Patients with ID Nutcracker Syndrome". (2021), 9-14. https://doi.org/10.5222/buchd.2021.54366
APA Yalçın Cömert H, Tural S, Şalcı G, Sarıhan H, İMAMOĞLU M (2021). Our Clinical Experiences in Patients with ID Nutcracker Syndrome. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, 11(1), 9 - 14. 10.5222/buchd.2021.54366
Chicago Yalçın Cömert Hatice Sonay,Tural Sema,Şalcı Gül,Sarıhan Haluk,İMAMOĞLU MUSTAFA Our Clinical Experiences in Patients with ID Nutcracker Syndrome. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi 11, no.1 (2021): 9 - 14. 10.5222/buchd.2021.54366
MLA Yalçın Cömert Hatice Sonay,Tural Sema,Şalcı Gül,Sarıhan Haluk,İMAMOĞLU MUSTAFA Our Clinical Experiences in Patients with ID Nutcracker Syndrome. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, vol.11, no.1, 2021, ss.9 - 14. 10.5222/buchd.2021.54366
AMA Yalçın Cömert H,Tural S,Şalcı G,Sarıhan H,İMAMOĞLU M Our Clinical Experiences in Patients with ID Nutcracker Syndrome. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi. 2021; 11(1): 9 - 14. 10.5222/buchd.2021.54366
Vancouver Yalçın Cömert H,Tural S,Şalcı G,Sarıhan H,İMAMOĞLU M Our Clinical Experiences in Patients with ID Nutcracker Syndrome. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi. 2021; 11(1): 9 - 14. 10.5222/buchd.2021.54366
IEEE Yalçın Cömert H,Tural S,Şalcı G,Sarıhan H,İMAMOĞLU M "Our Clinical Experiences in Patients with ID Nutcracker Syndrome." İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, 11, ss.9 - 14, 2021. 10.5222/buchd.2021.54366
ISNAD Yalçın Cömert, Hatice Sonay vd. "Our Clinical Experiences in Patients with ID Nutcracker Syndrome". İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi 11/1 (2021), 9-14. https://doi.org/10.5222/buchd.2021.54366