Bengi Gül TÜRK
(Dr. Selahattin Cizrelioğlu Cizre Devlet Hastanesi, Nöroloji Anabilim Dalı, Şırnak. Türkiye)
(Yedikule Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi Psikiyatri Anabilim Dalı, İstanbul. Türkiye)
Seher Naz YENİ
(İstanbul Üniversitesi-Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul. Türkiye)
Yıl: 2021Cilt: 27Sayı: 2ISSN: 1300-7157Sayfa Aralığı: 91 - 95İngilizce

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Acute Pain Perception in Patients with Psychogenic Non-Epileptic Seizures and its Relationship with Mood Disorders
Objectives: It has been found that pain response is higher in patients with depression and anxiety and also found higher in the patients with psychogenic non-epileptic seizures (PNES). However, these studies are limited in number and they are mainly focused on the chronic pain perception. We aimed to investigate anxiety and depression levels and the perception of acute pain along with childhood traumas among the patients with PNES. Methods: In our study, a total of 100 gender- and age-matched patients with PNES and 50 healthy controls were included in the study. The beck depression inventory (BDI), the beck anxiety inventory (BAI), and the childhood trauma questionnaire-28 were applied to all the participants. Pain perception was also evaluated by applying gradually increasing pressure with tension cuff while the participants were in a seated position. While the tension was about 180 mmHg, the participants were asked to evaluate their pain using the visual analog scale (VAS). Results: The major findings of our study are as follows: (i) The BDI and BAI scores were significantly higher in the PNES group than in the control group; (ii) VAS scores were significantly higher in the PNES group than in the control group; and (iii) among the PNES group, BAI scores were correlated with VAS scores. Conclusion: PNES is experienced by a heterogeneous patient group, and its underlying factors are still not well described. Depression and anxiety are common accompanying factors, and the pain response is higher in patients with PNES with high anxiety levels.
DergiAraştırma MakalesiErişime Açık
  • 1. Reuber M, Elger CE. Psychogenic nonepileptic seizures: Review and update. Epilepsy Behav 2003;4(3):205–16.
  • 2. Alsaadi TM, Marquez AV. Psychogenic nonepileptic seizures. Am Fam Physician 2005;72(5):849–56.
  • 3. O’Sullivan SS, Spillane JE, McMahon EM, Sweeney BJ, Galvin RJ, McNamara B, et al. Clinical characteristics and outcome of patients diagnosed with psychogenic nonepileptic seizures: A 5-year review. Epilepsy Behav 2007;11(1):77–84.
  • 4. Hubsch C, Baumann C, Hingray C, Gospodaru N, Vignal JP, Vespignani H, et al. Clinical classification of psychogenic non-epileptic seizures based on video-EEG analysis and automatic clustering. J Neurol Neurosurg Psychiatry 2011;82(9):955–60.
  • 5. Bodde NM, Brooks JL, Baker GA, Boon PA, Hendriksen JG, Mulder OG, et al. Psychogenic non-epileptic seizures-definition, etiology, treatment and prognostic issues: A critical review. Seizure 2009;18(8):543–53.
  • 6. Woo AK. Depression and anxiety in pain. Rev Pain 2010;4(1):8– 12.
  • 7. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961;4(6):561–71.
  • 8. Beck AT, Epstein N, Brown G, Steer RA. An inventory for measuring clinical anxiety: Psychometric properties. J Consult Clin Psychol 1988;56(6):893–7.
  • 9. Bernstein DP, Fink L, Handelsman L, Foote J, Lovejoy M, Wenzel K, et al. Initial reliability and validity of a new retrospective measure of child abuse and neglect. Am J Psychiatry 1994;151(8):1132–6.
  • 10. Şar V, Özturk E, İkikardeş E. Validity and reliability of the Turkish version of childhood trauma questionnaire (CTQ). Turk Klin J Med Sci 2012;32(4):1054–63.
  • 11. Reuber M. The etiology of psychogenic non-epileptic seizures: Toward a biopsychosocial model. Neurol Clin 2009;27(4):909– 24.
  • 12. Asadi-Pooya AA. Psychogenic nonepileptic seizures: A concise review. Neurol Sci 2017;38(6):935–40.
  • 13. Elliott JO, Charyton C. Biopsychosocial predictors of psychogenic non-epileptic seizures. Epilepsy Res 2014;108(9):1543– 53.
  • 14. Duncan R, Oto M. Predictors of antecedent factors in psychogenic nonepileptic attacks: Multivariate analysis. Neurology 2008;71(13):1000–5.
  • 15. Burket LW, Greenberg MS, Glick M. Burkett’s Textbook of Oral Medicine. 10th ed. Philadelphia, PA: Lippincott; 2003.
  • 16. Shega JW, Tiedt AD, Grant K, Dale W. Pain measurement in the national social life, health, and aging project: Presence, intensity, and location. J Gerontol B Psychol Sci Soc Sci 2014;69(2):S191–7.
  • 17. Kano M, Farmer AD, Aziz Q, Giampietro VP, Brammer MJ, Williams SC, et al. Sex differences in brain response to anticipated and experienced visceral pain in healthy subjects. Am J Physiol Gastrointest Liver Physiol 2013;304(8):G687–99.
  • 18. Fillingim RB, King CD, Ribeiro-Dasilva MC, Rahim-Williams B, Riley JL 3rd. Sex, gender, and pain: A review of recent clinical and experimental findings. J Pain 2009;10(5):447–85.
  • 19. Keogh E, Barlow C, Mounce C, Bond FW. Assessing the relationship between cold pressor pain responses and dimensions of the anxiety sensitivity profile in healthy men and women. Cogn Behav Ther 2006;35(4):198–206.
  • 20. Means-Christensen AJ, Roy-Byrne PP, Sherbourne CD, Craske MG, Stein MB. Relationships among pain, anxiety, and depression in primary care. Depress Anxiety 2008;25(7):593–600.
  • 21. Worz R. Pain in Depression, Depression in Pain. Pain Clinical Updates 2003. Vol. 11. United States: IASP; 2003.
  • 22. McWilliams LA, Cox BJ, Enns MW. Mood and anxiety disorders associated with chronic pain: An examination in a nationally representative sample. Pain 2003;106(1-2):127–33.

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