The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy

ILHAN ALGIN, DEMET; AYAS, HAKAN MUSA; özözen ayas, zeynep; ERDINC, OGUZ; Adıyaman, Esma; UNCU, GÜLGÜN

The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy

Zeynep ÖZÖZEN AYAS, (Eskişehir Şehir Hastanesi, Nöroloji Anabilim Dalı, Eskişehir. Türkiye)

Hakan Musa AYAS, (Eskişehir Şehir Hastanesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Eskişehir. Türkiye)

Esma ADIYAMAN, (Eskişehir Şehir Hastanesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Eskişehir. Türkiye)

Gülgün UNCU, (Eskişehir Şehir Hastanesi, Nöroloji Anabilim Dalı, Eskişehir. Türkiye)

Demet İLHAN ALGIN, (Eskişehir Osmangazi Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Eskişehir. Türkiye)

Oğuz Osman ERDİNÇ (Eskişehir Osmangazi Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Eskişehir. Türkiye)

Epilepsi

1 0

Yıl: 2021 Cilt: 27 Sayı: 2 Sayfa Aralığı: 123 - 126 Metin Dili: İngilizce İndeks Tarihi: 17-02-2022

The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy

Öz:

The risk of suicide attempt in patients with epilepsy is higher than in the general population. Psychiatric diseases can be seen in patients with epilepsy. It is also known that antiepileptic drugs may have an increased risk of suicide attempts. However, it is thought that suicide attempts should not be attributed to just psychiatric diseases and antiepileptic drugs. It has been reported that the rate of suicide attempts is also higher in patients with epilepsy without psychiatric diseases. Suicide attempts during pregnancy are less common than in other periods. This article presents 28-weeks pregnant women with epilepsy who had taken high-dose multidrug for suicide attempt and the management and treatment of the patient. Rarely, an alteration of consciousness in pregnant women with epilepsy may be a result of suicide attempt. Clinicians must be alert to risk of suicide attempt of pregnant woman and patients with epilepsy

Anahtar Kelime:

Zorlu Bir Olgunun Yönetimi: Epileptik Bir Gebenin Çoklu İlaç Alımı ile Suisidal Girişimi

Öz:

Epilepsili hastalarda intihar girişimi riski, genel popülasyona göre artmıştır. Psikiyatrik hastalıklar epilepsi hastalarında görülebilmektedir. Ayrıca, antiepileptik ilaçların artmış intihar girişimi riskine sahip olduğu bilinmektedir. Ancak intihar girişimleri sadece psikiyatrik hastalıklar ve antiepileptik ilaçlara bağlanmamalıdır. Psikiyatrik hastalığı olmayan epilepsi hastalarında da suisidal girişim oranının yüksek olduğu bildirilmiştir. Gebelikteki suisidal girişimler ise diğer dönemlere göre daha az görülmektedir. Bu yazıda, suisidal amaçlı yüksek doz çoklu ilaç alımı olan 28 haftalık gebe bir epilepsi hastası ile bu hastaya yaklaşım ve tedavi süreci sunulmuştur. Epileptik gebe hastada ani bilinç değişikliği nadir de olsa, ilaç alımı ile suisidal girişimin bir sonucu olabilir. Klinisyenler, intihar girişimi riski açısından gebe ve epilepsi hastalarında dikkatli olmalıdır.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. World Health Organization. Preventing suicide a resource for media professionals. Available at: http://www.who.int/mental_health/media/en/426.pdf. Accessed June 15, 2020.
2. World Health Organization. Figures and facts about suicide. Available at: http://apps.who.int/iris/handle/10665/66097. Accessed June 15, 2020.
3. Bell GS, Gaitatzis A, Bell CL, Johnson AL, Sander JW. Suicide in people with epilepsy: how great is the risk? Epilepsia 2009;50(8):1933–42.
4. Christensen J, Vestergaard M, Mortensen PB, Sidenius P, Agerbo E. Epilepsy and risk of suicide: a population-based case-control study. Lancet Neurol 2007;6(8):693–8.
5. Hara E, Akanuma N, Adachi N, Hara K, Koutroumanidis M. Suicide attempts in adult patients with idiopathic generalized epilepsy. Psychiatry Clin Neurosci 2009;63(2):225–9.
6. Lara MA, Letechipia G. Suicidal ideation and suicidal behavior in pregnancy. Salud Ment 2009;32:381–7.
7. Gaitatzis A, Trimble MR, Sander JW. The psychiatric comorbidity of epilepsy. Acta Neurol Scand 2004;110(4):207–20.
8. Harris EC, Barraclough B. Suicide as an outcome for mental disorders. A meta-analysis. Br J Psychiatry 1997;170:205–28.
9. Eskin M, Kaynak-Demir H, Demir S. Same-sex sexual orientation, childhood sexual abuse, and suicidal behavior in university students in Turkey. Arch Sex Behav 2005;34(2):185–95.
10. US Department of Health and Human Services Food and Drug Administration. Statistical review and evaluation antiepileptic drugs and s uicidality Avaliable at: https://www.fda.gov/files/ drugs/published/Statistical-Review-and-Evaluation--Antiepileptic-Drugs-and-Suicidality.pdf. Accessed May 23, 2020.
11. Mula M, Sander JW. Suicidal ideation in epilepsy and levetiracetam therapy. Epilepsy Behav 2007;11(1):130–2.
12. Molokwu OA, Ezeala-Adikaibe BA, Onwuekwe IO. Levetiracetam-induced rage and suicidality: Two case reports and review of literature. Epilepsy Behav Case Rep 2015;4:79–81.
13. Villari V, Rocca P, Frieri T, Bogetto F. Psychiatric symptoms related to the use of lamotrigine: a review of the literature. Funct Neurol 2008;23(3):133–6.
14. Zengin Y, Gündüz E, Dursun R, İçer M, Durgun HM, Kara E, et al. Evaluation of pregnant patients admitted to the emergency department with suicide attempt. Journal of Clinical and Experimental Investigations 2015;6(2):115–-20.
15. Karadaş S, Güler A, Aydın I. A retrospective analysis of acute poisoning during pregnancy. J Turk Ger Gynecol Assoc 2011;12(4):199–203.
16. Uzkeser M, Sarıtemur M, Aköz A, Bayramoğlu A, Emet M. Gebelerde intihar amaçlı ilaç zehirlenmelerinin gebe olmayanlara göre farkı var mı? Tr J Emerg Med 2012;12(4):169–74.
17. Sein Anand J, Chodorowski Z, Ciechanowicz R, Klimaszyk D, Lukasik-Głebocka M. Acute suicidal self-poisonings during pregnancy. Przegl Lek 2005;62(6):434–5.
18. Czeizel AE. Attempted suicide and pregnancy. J Inj Violence Res 2011;3(1):45–54.
19. Appleby L. Suicide during pregnancy and in the first postnatal year. BMJ 1991;302(6769):137–40.
20. Honca M, Şahin Ş. Gebelikte yüksek doz demir alımına bağlı gelişen zehirlenme. Türk Anest Rean Der Dergisi 2011;39(4):207–10.

APA	özözen ayas z, AYAS H, Adıyaman E, UNCU G, ILHAN ALGIN D, ERDINC O (2021). The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. , 123 - 126.
Chicago	özözen ayas zeynep,AYAS HAKAN MUSA,Adıyaman Esma,UNCU GÜLGÜN,ILHAN ALGIN DEMET,ERDINC OGUZ The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. (2021): 123 - 126.
MLA	özözen ayas zeynep,AYAS HAKAN MUSA,Adıyaman Esma,UNCU GÜLGÜN,ILHAN ALGIN DEMET,ERDINC OGUZ The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. , 2021, ss.123 - 126.
AMA	özözen ayas z,AYAS H,Adıyaman E,UNCU G,ILHAN ALGIN D,ERDINC O The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. . 2021; 123 - 126.
Vancouver	özözen ayas z,AYAS H,Adıyaman E,UNCU G,ILHAN ALGIN D,ERDINC O The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. . 2021; 123 - 126.
IEEE	özözen ayas z,AYAS H,Adıyaman E,UNCU G,ILHAN ALGIN D,ERDINC O "The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy." , ss.123 - 126, 2021.
ISNAD	özözen ayas, zeynep vd. "The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy". (2021), 123-126.

APA	özözen ayas z, AYAS H, Adıyaman E, UNCU G, ILHAN ALGIN D, ERDINC O (2021). The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. Epilepsi, 27(2), 123 - 126.
Chicago	özözen ayas zeynep,AYAS HAKAN MUSA,Adıyaman Esma,UNCU GÜLGÜN,ILHAN ALGIN DEMET,ERDINC OGUZ The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. Epilepsi 27, no.2 (2021): 123 - 126.
MLA	özözen ayas zeynep,AYAS HAKAN MUSA,Adıyaman Esma,UNCU GÜLGÜN,ILHAN ALGIN DEMET,ERDINC OGUZ The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. Epilepsi, vol.27, no.2, 2021, ss.123 - 126.
AMA	özözen ayas z,AYAS H,Adıyaman E,UNCU G,ILHAN ALGIN D,ERDINC O The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. Epilepsi. 2021; 27(2): 123 - 126.
Vancouver	özözen ayas z,AYAS H,Adıyaman E,UNCU G,ILHAN ALGIN D,ERDINC O The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy. Epilepsi. 2021; 27(2): 123 - 126.
IEEE	özözen ayas z,AYAS H,Adıyaman E,UNCU G,ILHAN ALGIN D,ERDINC O "The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy." Epilepsi, 27, ss.123 - 126, 2021.
ISNAD	özözen ayas, zeynep vd. "The Management of a Difficult Case: a Suicide Attempt by the Ingestion of Multiple Drugs by a Pregnant woman with Epilepsy". Epilepsi 27/2 (2021), 123-126.