Persistent Subacute Thyroiditis Post SARS-CoV-2
Vaccine in a Male Patient with Positive Thyroid
Autoantibodies

topaloğlu, seda nur; Tekin, Sakin; BAYRAKTAROĞLU, TANER; Topaloğlu, Ömercan

Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies

Ömercan TOPALOĞLU, (Zonguldak Bülent Ecevit Üniversitesi, Tıp Fakültesi, Endokrinoloji ve Metabolizma Anabilim Dalı, Zonguldak, TÜRKİYE)

Sakin TEKİN, (Zonguldak Bülent Ecevit Üniversitesi, Tıp Fakültesi, Endokrinoloji ve Metabolizma Anabilim Dalı, Zonguldak, TÜRKİYE)

Seda Nur TOPALOĞLU, (Zonguldak Bülent Ecevit Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Zonguldak, TÜRKİYE)

Taner BAYRAKTAROĞLU (Zonguldak Bülent Ecevit Üniversitesi, Tıp Fakültesi, Endokrinoloji ve Metabolizma Anabilim Dalı, Zonguldak, TÜRKİYE)

Turkish Journal of Endocrinology and Metabolism

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Yıl: 2022 Cilt: 26 Sayı: 1 Sayfa Aralığı: 48 - 54 Metin Dili: İngilizce İndeks Tarihi: 26-06-2022

Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies

Öz:

Subacute thyroiditis (SAT) has been recently associated with severe acute respiratory syndrome-coronavirus-2 infection or vaccines against it. We report a case of a 41-yearold male patient who developed persistent SAT after the coronavirus disease-2019 (COVID-19) vaccination. He presented with sore throat and neck pain after the first dose of the COVID-19 vaccine (CoronaVac®). There was no history of a recent viral infection. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were elevated, thyroidstimulating hormone (TSH) and free thyroxine (fT4) were normal, COVID-19 polymerase chain reaction test was negative, and sonography showed thyroiditis in the right lobe. The symptoms resolved after treatment with methylprednisolone. However, 2 weeks after the second dose of the vaccine, the patient suffered from neck pain and hoarseness. TSH and fT4 were normal, but anti-thyroid peroxidase (antiTPO), anti-thyroglobulin (anti-Tg), ESR, and CRP were elevated. Sonography revealed thyroiditis in the left lobe. The patient was treated with ibuprofen. On follow-up, hypothyroidism was diagnosed, and levothyroxine started. Hence, the clinicians should suspect the possibility of SAT in the vaccinated subjects.

Anahtar Kelime:

Tiroid Otoantikorları Pozitif Olan Erkek Hastada İnaktif SARS-CoV-2 Aşısından Sonra Gelişen Persistan Subakut Tiroidit

Öz:

Subakut tiroidit (SAT), son zamanlarda şiddetli akut solunum sendromu-koronavirüs-2 enfeksiyonu veya buna karşı geliştirilen aşılarla ilişkilendirilmektedir. Koronavirüs hastalığı-2019 [coronavirus disease-2019 (COVID-19)] aşılaması sonrasında persistan SAT gelişen 41 yaşında erkek hastamızı sunuyoruz. COVID-19 aşısının (CoronaVac®) ilk dozundan sonra boğaz ağrısı ve boyun ağrısı ile başvurdu. Yakın zamanda viral enfeksiyon öyküsü yoktu. Eritrosit sedimentasyon hızı (ESH) ve C-reaktif protein (CRP) yüksekti, tiroidstimüle edici hormon (TSH) ve serbest tiroksin (sT4) normaldi, COVID-19 polimeraz zincir reaksiyonu testi negatifti ve sonografide sağ lobta tiroidit mevcuttu. Metilprednizolon tedavisi ile semptomlar geriledi. Ancak aşının 2. dozundan 2 hafta sonra hasta boyun ağrısı ve ses kısıklığından yakındı. TSH ve sT4 normaldi, anti-tiroid peroksidaz, anti-tiroglobülin, ESH ve CRP yükseldi. Sonografide sol lobta tiroidit izlendi. Hasta ibuprofen ile tedavi edildi. Takipte, hipotiroidizm tanısıyla levotiroksin başlandı. Dolayısıyla klinisyenler aşılanmış kişilerde SAT olasılığını akılda tutmalıdır

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

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APA	Topaloğlu Ö, Tekin S, topaloğlu s, BAYRAKTAROĞLU T (2022). Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. , 48 - 54.
Chicago	Topaloğlu Ömercan,Tekin Sakin,topaloğlu seda nur,BAYRAKTAROĞLU TANER Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. (2022): 48 - 54.
MLA	Topaloğlu Ömercan,Tekin Sakin,topaloğlu seda nur,BAYRAKTAROĞLU TANER Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. , 2022, ss.48 - 54.
AMA	Topaloğlu Ö,Tekin S,topaloğlu s,BAYRAKTAROĞLU T Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. . 2022; 48 - 54.
Vancouver	Topaloğlu Ö,Tekin S,topaloğlu s,BAYRAKTAROĞLU T Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. . 2022; 48 - 54.
IEEE	Topaloğlu Ö,Tekin S,topaloğlu s,BAYRAKTAROĞLU T "Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies." , ss.48 - 54, 2022.
ISNAD	Topaloğlu, Ömercan vd. "Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies". (2022), 48-54.

APA	Topaloğlu Ö, Tekin S, topaloğlu s, BAYRAKTAROĞLU T (2022). Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. Turkish Journal of Endocrinology and Metabolism, 26(1), 48 - 54.
Chicago	Topaloğlu Ömercan,Tekin Sakin,topaloğlu seda nur,BAYRAKTAROĞLU TANER Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. Turkish Journal of Endocrinology and Metabolism 26, no.1 (2022): 48 - 54.
MLA	Topaloğlu Ömercan,Tekin Sakin,topaloğlu seda nur,BAYRAKTAROĞLU TANER Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. Turkish Journal of Endocrinology and Metabolism, vol.26, no.1, 2022, ss.48 - 54.
AMA	Topaloğlu Ö,Tekin S,topaloğlu s,BAYRAKTAROĞLU T Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. Turkish Journal of Endocrinology and Metabolism. 2022; 26(1): 48 - 54.
Vancouver	Topaloğlu Ö,Tekin S,topaloğlu s,BAYRAKTAROĞLU T Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies. Turkish Journal of Endocrinology and Metabolism. 2022; 26(1): 48 - 54.
IEEE	Topaloğlu Ö,Tekin S,topaloğlu s,BAYRAKTAROĞLU T "Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies." Turkish Journal of Endocrinology and Metabolism, 26, ss.48 - 54, 2022.
ISNAD	Topaloğlu, Ömercan vd. "Persistent Subacute Thyroiditis Post SARS-CoV-2 Vaccine in a Male Patient with Positive Thyroid Autoantibodies". Turkish Journal of Endocrinology and Metabolism 26/1 (2022), 48-54.