Pituitary Gland as a Rare Primary Localization of
Lymphoma

Lymphomas are the rare causes in the differential diagnosis of pituitary masses. While pituitary infiltration by lymphomas is relatively more frequent, isolated lymphoma associated with the pituitary gland is much rarer. We presented a case of a 64-year-old female patient who was admitted to the hospital due to headache, diplopia and decreased visual acuity. Although the stated preoperative diagnosis was parasellar meningioma, the pathological diagnosis was given as isolated primary pituitary lymphoma after ruling out any other foci. After the definitive diagnosis, the patient underwent chemoradiotherapy. However, despite treatment, the patient died due to pulmonary sepsis. Primary pituitary lymphoma is an extremely rare condition generally seen in elderly and/or immunosuppressive patients. In order to establish an effective therapeutic strategy, it is extremely crucial to distinguish between primary and secondary lymphomas. However, the recent evidence for a standardized treatment protocol is still limited due to the small number of cases reported to date.

Anahtar Kelime:

Nadir Bir Primer Lenfoma Lokalizasyonu: Hipofiz Bezi

Öz:

Lenfomalar, son derece nadir görülmekte olup, hipofiz kitlelerinin ayırıcı tanısında göz önünde bulundurulmalıdır. Lenfomaların pituiter infiltrasyonları göreceli olarak daha sık karşımıza gelirken, hipofiz bezinin izole primer lenfoması çok daha nadirdir. Bu olguda, hastaneye baş ağrısı, çift görme ve görme keskinliğinde azalma şikâyeti ile başvuran 64 yaşında bir kadın hastayı sunduk. Preoperatif ön tanısı parasellar menenjioma olan hastaya, vücutta herhangi bir ek odak olmadığının gösterilmesinin ardından izole primer pituiter lenfoma tanısı kondu. Tanısının kesinleşmesinin ardından hastaya kemoradyoterapi başlandı. Kemoterapi ve radyoterapinin hızla başlanmasına karşın hasta, tedavinin 3. ayında akciğer enfeksiyonuna sekonder sepsis nedeniyle kaybedildi. Pituiter lenfomalar son derece nadir olup, ileri yaşta ve/veya immünsuprese hastalarda daha sık görülmektedir. Primer ve sekonder lenfoma ayırıcı tanısının yapılması, etkin bir tedavi belirlemek için çok önemlidir. Ancak günümüzde raporlanmış olguların az sayıda olması nedeniyle standardize bir tedavi protokolü için henüz yeterli kanıt bulunmamaktadır.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

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APA	Özbaş B, canöz ö, Guven Z, Ökçesiz İ, Dursun H, Selçuklu A, Yılmaz H, karaca Z, Unluhizarci K (2022). Pituitary Gland as a Rare Primary Localization of Lymphoma. , 55 - 60.
Chicago	Özbaş Burak,canöz özlem,Guven Zeynep Tugba,Ökçesiz İzzet,Dursun Hüseyin,Selçuklu Ahmet,Yılmaz Hatice,karaca Zuleyha,Unluhizarci Kursad Pituitary Gland as a Rare Primary Localization of Lymphoma. (2022): 55 - 60.
MLA	Özbaş Burak,canöz özlem,Guven Zeynep Tugba,Ökçesiz İzzet,Dursun Hüseyin,Selçuklu Ahmet,Yılmaz Hatice,karaca Zuleyha,Unluhizarci Kursad Pituitary Gland as a Rare Primary Localization of Lymphoma. , 2022, ss.55 - 60.
AMA	Özbaş B,canöz ö,Guven Z,Ökçesiz İ,Dursun H,Selçuklu A,Yılmaz H,karaca Z,Unluhizarci K Pituitary Gland as a Rare Primary Localization of Lymphoma. . 2022; 55 - 60.
Vancouver	Özbaş B,canöz ö,Guven Z,Ökçesiz İ,Dursun H,Selçuklu A,Yılmaz H,karaca Z,Unluhizarci K Pituitary Gland as a Rare Primary Localization of Lymphoma. . 2022; 55 - 60.
IEEE	Özbaş B,canöz ö,Guven Z,Ökçesiz İ,Dursun H,Selçuklu A,Yılmaz H,karaca Z,Unluhizarci K "Pituitary Gland as a Rare Primary Localization of Lymphoma." , ss.55 - 60, 2022.
ISNAD	Özbaş, Burak vd. "Pituitary Gland as a Rare Primary Localization of Lymphoma". (2022), 55-60.

APA	Özbaş B, canöz ö, Guven Z, Ökçesiz İ, Dursun H, Selçuklu A, Yılmaz H, karaca Z, Unluhizarci K (2022). Pituitary Gland as a Rare Primary Localization of Lymphoma. Turkish Journal of Endocrinology and Metabolism, 26(1), 55 - 60.
Chicago	Özbaş Burak,canöz özlem,Guven Zeynep Tugba,Ökçesiz İzzet,Dursun Hüseyin,Selçuklu Ahmet,Yılmaz Hatice,karaca Zuleyha,Unluhizarci Kursad Pituitary Gland as a Rare Primary Localization of Lymphoma. Turkish Journal of Endocrinology and Metabolism 26, no.1 (2022): 55 - 60.
MLA	Özbaş Burak,canöz özlem,Guven Zeynep Tugba,Ökçesiz İzzet,Dursun Hüseyin,Selçuklu Ahmet,Yılmaz Hatice,karaca Zuleyha,Unluhizarci Kursad Pituitary Gland as a Rare Primary Localization of Lymphoma. Turkish Journal of Endocrinology and Metabolism, vol.26, no.1, 2022, ss.55 - 60.
AMA	Özbaş B,canöz ö,Guven Z,Ökçesiz İ,Dursun H,Selçuklu A,Yılmaz H,karaca Z,Unluhizarci K Pituitary Gland as a Rare Primary Localization of Lymphoma. Turkish Journal of Endocrinology and Metabolism. 2022; 26(1): 55 - 60.
Vancouver	Özbaş B,canöz ö,Guven Z,Ökçesiz İ,Dursun H,Selçuklu A,Yılmaz H,karaca Z,Unluhizarci K Pituitary Gland as a Rare Primary Localization of Lymphoma. Turkish Journal of Endocrinology and Metabolism. 2022; 26(1): 55 - 60.
IEEE	Özbaş B,canöz ö,Guven Z,Ökçesiz İ,Dursun H,Selçuklu A,Yılmaz H,karaca Z,Unluhizarci K "Pituitary Gland as a Rare Primary Localization of Lymphoma." Turkish Journal of Endocrinology and Metabolism, 26, ss.55 - 60, 2022.
ISNAD	Özbaş, Burak vd. "Pituitary Gland as a Rare Primary Localization of Lymphoma". Turkish Journal of Endocrinology and Metabolism 26/1 (2022), 55-60.