Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?
Yıl: 2021 Cilt: 14 Sayı: 3 Sayfa Aralığı: 598 - 603 Metin Dili: İngilizce DOI: 10.31362/patd.809407 İndeks Tarihi: 16-06-2022
Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?
Öz: Purpose: Neutrophile-Lymphocyte (NLR) and Platelet-Lymphocyte ratio (PLR) comparison is an easy to use
and cost-effective method in diagnosis of some cancers and diseases. In this study, we aimed to investigate if
NLR/PLR ratio evaluation could be utilized in diagnosis of testicular malignencies especially in early-term with
occult metastasis.
Materials and methods: A total of 40 patients at stage-I, who have undergone radical inguinal orchiectomy
intervention for testicular tumor between 2015 and 2019, and 43 control individuals without any testicular
complaints were included in this retrospective study. The relationship between pathological risk factors for occult
metastatic disease in Stage-I testicular cancer and NLR/PLR values were investigated.
Results: The average age was 30.05 years, and there was no significant difference between the groups by
means of age (p=0.150). The NLR and PLR values of the tumor group were prominently higher in the patient
group, when compared with the control group (p=0.001 and p=0.016, respectively). In the correlation analysis
between risk-factors for occult metastatic disease in Stage-I testicular cancer and NLR/PLR, we have found that
only a significant correlation was present in terms of tumor size.
Conclusion: As a result, we have concluded that NLR increases in all types of testicular tumors. We suggest
that higher NLR ratio values can be used as prognostic marker in clinical practice.
Anahtar Kelime: Nötrofil lenfosit oranı evre 1 testis tümöründe okkült metastaz parametrelerinde belirteç olabilir mi?
Öz: Amaç: Nötrofil-Lenfosit ve Trombosit-Lenfosit oranı (NLR/PLR) karşılaştırması, bazı kanserlerin ve hastalıkların
tanısında kullanımı kolay ve düşük maliyetli bir yöntemdir. Bu çalışmada, özellikle okkült metastazlı erken dönem
testis malignitelerinin tanısında NLR/PLR oranı değerlendirmesinin kullanılıp kullanılamayacağını araştırmayı
amaçladık.
Gereç ve yöntem: 2015-2019 yılları arasında testis tümörü için radikal inguinal orşiektomi müdahalesi yapılan
hastalar retrospektif olarak incelendi. Çalışmaya testis tümör evre-I olan 40 hasta ve herhangi bir testis şikayeti
olmayan 43 hasta kontrol grubu olarak çalışmaya dahil edildi. Evre-I testis kanserinde okkült metastatik hastalık
için patolojik risk faktörleri ile NLR/PLR değerleri arasındaki ilişki araştırıldı.
Bulgular: Hastaların yaş ortalaması 30,05 yıl idi ve gruplar arasında yaş bakımından anlamlı fark yoktu
(p=0,150). Tümör grubunun NLR ve PLR oranı değerleri testis tümörlü hastalarda kontrol grubuna göre belirgin
olarak yüksekti (sırasıyla p=0,001 ve p=0,016). Evre-I testis kanseri ve NLR/PLR'de okkült metastatik hastalık
için risk faktörleri arasındaki korelasyon analizinde sadece tümör boyutu açısından anlamlı bir korelasyon
olduğunu bulduk.
Sonuç: Sonuç olarak, tüm testis tümörlerinde NLR'nin arttığı sonucuna vardık. Klinik uygulamada prognostik
belirteç olarak daha yüksek NLR oranı değerlerinin kullanılabileceğini önermekteyiz.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA | baser a, ARAS B (2021). Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. , 598 - 603. 10.31362/patd.809407 |
Chicago | baser aykut,ARAS Bekir Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. (2021): 598 - 603. 10.31362/patd.809407 |
MLA | baser aykut,ARAS Bekir Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. , 2021, ss.598 - 603. 10.31362/patd.809407 |
AMA | baser a,ARAS B Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. . 2021; 598 - 603. 10.31362/patd.809407 |
Vancouver | baser a,ARAS B Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. . 2021; 598 - 603. 10.31362/patd.809407 |
IEEE | baser a,ARAS B "Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?." , ss.598 - 603, 2021. 10.31362/patd.809407 |
ISNAD | baser, aykut - ARAS, Bekir. "Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?". (2021), 598-603. https://doi.org/10.31362/patd.809407 |
APA | baser a, ARAS B (2021). Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. Pamukkale Tıp Dergisi, 14(3), 598 - 603. 10.31362/patd.809407 |
Chicago | baser aykut,ARAS Bekir Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. Pamukkale Tıp Dergisi 14, no.3 (2021): 598 - 603. 10.31362/patd.809407 |
MLA | baser aykut,ARAS Bekir Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. Pamukkale Tıp Dergisi, vol.14, no.3, 2021, ss.598 - 603. 10.31362/patd.809407 |
AMA | baser a,ARAS B Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. Pamukkale Tıp Dergisi. 2021; 14(3): 598 - 603. 10.31362/patd.809407 |
Vancouver | baser a,ARAS B Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?. Pamukkale Tıp Dergisi. 2021; 14(3): 598 - 603. 10.31362/patd.809407 |
IEEE | baser a,ARAS B "Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?." Pamukkale Tıp Dergisi, 14, ss.598 - 603, 2021. 10.31362/patd.809407 |
ISNAD | baser, aykut - ARAS, Bekir. "Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?". Pamukkale Tıp Dergisi 14/3 (2021), 598-603. https://doi.org/10.31362/patd.809407 |