A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus
Yıl: 2022 Cilt: 23 Sayı: 2 Sayfa Aralığı: 106 - 110 Metin Dili: İngilizce DOI: 10.4274/jtgga.galenos.2021.2021-9-28 İndeks Tarihi: 16-06-2022
A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus
Öz: Objective: We aimed to investigate maternal plasma endoplasmic reticulum to nucleus signalling-1 (ERN-1) concentrations in patients
diagnosed with gestational diabetes mellitus (GDM).
Material and Methods: This was a cross-sectional study of 57 pregnant women with GDM and 40 gestational age- and body mass indexmatched, healthy pregnant controls, conducted between August 2020 and November 2020. Plasma ERN-1 levels, other laboratory markers of
insulin resistance, and demographic characteristics were compared between groups.
Results: Fasting glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), hemoglobin A1c and plasma ERN-1 levels
were significantly higher in the GDM group than in the healthy controls (p<0.001). Positive correlation was found between ERN-1 levels and
HOMA-IR values (p=0.016). The optimal cut-off value for ERN-1 to diagnose GDM was 6.960 ng/mL, with a sensitivity of 78.9% and a specificity
of 75.0% (p<0.001).
Conclusion: ERN-1 may be considered as a new marker for diagnosis of GDM and may also be a potential target in studies of GDM treatment
modalities. (J Turk Ger Gynecol Assoc 2022; 23: 106-10)
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Süzen çaypınar S, BEHRAM M (2022). A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. , 106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| Chicago | Süzen çaypınar Sema,BEHRAM MUSTAFA A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. (2022): 106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| MLA | Süzen çaypınar Sema,BEHRAM MUSTAFA A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. , 2022, ss.106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| AMA | Süzen çaypınar S,BEHRAM M A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. . 2022; 106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| Vancouver | Süzen çaypınar S,BEHRAM M A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. . 2022; 106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| IEEE | Süzen çaypınar S,BEHRAM M "A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus." , ss.106 - 110, 2022. 10.4274/jtgga.galenos.2021.2021-9-28 |
| ISNAD | Süzen çaypınar, Sema - BEHRAM, MUSTAFA. "A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus". (2022), 106-110. https://doi.org/10.4274/jtgga.galenos.2021.2021-9-28 |
| APA | Süzen çaypınar S, BEHRAM M (2022). A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. Journal of the Turkish-German Gynecological Association, 23(2), 106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| Chicago | Süzen çaypınar Sema,BEHRAM MUSTAFA A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. Journal of the Turkish-German Gynecological Association 23, no.2 (2022): 106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| MLA | Süzen çaypınar Sema,BEHRAM MUSTAFA A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. Journal of the Turkish-German Gynecological Association, vol.23, no.2, 2022, ss.106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| AMA | Süzen çaypınar S,BEHRAM M A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. Journal of the Turkish-German Gynecological Association. 2022; 23(2): 106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| Vancouver | Süzen çaypınar S,BEHRAM M A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus. Journal of the Turkish-German Gynecological Association. 2022; 23(2): 106 - 110. 10.4274/jtgga.galenos.2021.2021-9-28 |
| IEEE | Süzen çaypınar S,BEHRAM M "A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus." Journal of the Turkish-German Gynecological Association, 23, ss.106 - 110, 2022. 10.4274/jtgga.galenos.2021.2021-9-28 |
| ISNAD | Süzen çaypınar, Sema - BEHRAM, MUSTAFA. "A novel marker endoplasmic reticulum to nucleus signalling-1 in the diagnosis of gestational diabetes mellitus". Journal of the Turkish-German Gynecological Association 23/2 (2022), 106-110. https://doi.org/10.4274/jtgga.galenos.2021.2021-9-28 |
