SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM
Yıl: 2022 Cilt: 11 Sayı: 1 Sayfa Aralığı: 22 - 30 Metin Dili: İngilizce DOI: 10.18038/aubtdc.1051707 İndeks Tarihi: 23-06-2022
SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM
Öz: In this research article, a new chromatographic method ultra-performance liquid chromatography (UPLC) method was
developed for the quantification of ivermectin (IMT)-preziquantel (PRZQ) in a two-component mixture and veterinary dosage
form mixture. The separation of the studied veterinary drugs (IMT and PRZQ) was carried out on Waters Acquity ® BEH C18
column (50mm x 2.1 mm i.d., 1.7 m) using a mobile phase consisting of water-acetonitrile-methanol (10:70:20, v/v). In the
chromatographic analysis, flow rate was 0.38 mL/min, and column temperature was maintained at 42 0C. The chromatographic
detection of IMT and PRZQ was made at the wavelength of 220.0 and 245.0 nm, respectively. The developed UPLC method
was validated and applied to real samples consisting of IMT and PRZQ. Recovery assay results were found to be 100.4 % for
PRZQ and 101.8 % for IMT. The presented UPLC method is introduced as an alternative choice for the quality control of
pharmaceutical preparations containing these drugs. For the quality control of pharmaceutical preparations containing these
drugs, the presented UPLC method is introduced as an alternative experimental analysis choice
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | BÜKER E, yaşar N, Dinç E (2022). SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. , 22 - 30. 10.18038/aubtdc.1051707 |
| Chicago | BÜKER Eda,yaşar Nagehan,Dinç Erdal SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. (2022): 22 - 30. 10.18038/aubtdc.1051707 |
| MLA | BÜKER Eda,yaşar Nagehan,Dinç Erdal SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. , 2022, ss.22 - 30. 10.18038/aubtdc.1051707 |
| AMA | BÜKER E,yaşar N,Dinç E SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. . 2022; 22 - 30. 10.18038/aubtdc.1051707 |
| Vancouver | BÜKER E,yaşar N,Dinç E SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. . 2022; 22 - 30. 10.18038/aubtdc.1051707 |
| IEEE | BÜKER E,yaşar N,Dinç E "SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM." , ss.22 - 30, 2022. 10.18038/aubtdc.1051707 |
| ISNAD | BÜKER, Eda vd. "SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM". (2022), 22-30. https://doi.org/10.18038/aubtdc.1051707 |
| APA | BÜKER E, yaşar N, Dinç E (2022). SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi C- yaşam Bilimleri ve Biyoteknoloji (Online), 11(1), 22 - 30. 10.18038/aubtdc.1051707 |
| Chicago | BÜKER Eda,yaşar Nagehan,Dinç Erdal SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi C- yaşam Bilimleri ve Biyoteknoloji (Online) 11, no.1 (2022): 22 - 30. 10.18038/aubtdc.1051707 |
| MLA | BÜKER Eda,yaşar Nagehan,Dinç Erdal SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi C- yaşam Bilimleri ve Biyoteknoloji (Online), vol.11, no.1, 2022, ss.22 - 30. 10.18038/aubtdc.1051707 |
| AMA | BÜKER E,yaşar N,Dinç E SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi C- yaşam Bilimleri ve Biyoteknoloji (Online). 2022; 11(1): 22 - 30. 10.18038/aubtdc.1051707 |
| Vancouver | BÜKER E,yaşar N,Dinç E SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi C- yaşam Bilimleri ve Biyoteknoloji (Online). 2022; 11(1): 22 - 30. 10.18038/aubtdc.1051707 |
| IEEE | BÜKER E,yaşar N,Dinç E "SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM." Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi C- yaşam Bilimleri ve Biyoteknoloji (Online), 11, ss.22 - 30, 2022. 10.18038/aubtdc.1051707 |
| ISNAD | BÜKER, Eda vd. "SIMULTANEOUS QUANTITATIVE ANALYSIS OF TWO ANTHELMINTIC DRUGS IN A VETERINARY DOSAGE FORM". Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi C- yaşam Bilimleri ve Biyoteknoloji (Online) 11/1 (2022), 22-30. https://doi.org/10.18038/aubtdc.1051707 |
