Fisun AKDENİZ
(Ege Üniversitesi, Tıp Fakültesi, Psikiyatri Anabilim Dalı, İzmir, Türkiye)
Figen KARADAĞ
(Bakırköy Ruh ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi, AMATEM Kliniği, İstanbul, Türkiye)
Yıl: 2006Cilt: 17Sayı: 4ISSN: 1300-2163 / 2651-3463Sayfa Aralığı: 296 - 304Türkçe

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Adet döngüsünün duygudurum bozuklukları üzerine etkisi var mıdır?
Amaç: Bu yazıda, adet döngüsü ve duygudurum bozuklukları arasındaki ilişki ile ilgili kanıtların sunulması amaçlanmıştır. Yöntem: Depresyon, iki uçlu bozukluk, premenstrüel sendrom, premenstrüel alevlenme, premenstrüel disforik bozukluk, adet döngüsü ve özkıyım anahtar sözcükleri kullanılarak 1955-2005 yılları arasında İngilizce ve Türkçe yayınlanmış tüm makaleler incelenmiştir. İlk çalışmalarda adet öncesi dönemde psikiyatri kliniklerine başvuruda artış olduğu ve özkıyım davranışı ile belirli bir adet döngüsü evresi arasında ilişki olduğu gösterilmiştir. Bulgular: Verilere göre ruhsal bozukluğu olan üreme çağındaki kadınların hastalık belirtileri, adet döngüsü sırasında dalgalanır. Bazı veriler, bir grup kadın hastanın, adet döngüsünün belirli bir evresinde var olan ruhsal hastalıklarının (özellikle de majör depresif dönem) alevlenmesi veya yeni bir hastalık dönemi yaşaması açısından yatkınlık artışı gösterdiklerini ileri sürmüştür. İki uçlu duygudurum bozukluğunun gidişinde duygudurum dalgalanmalarının yönü ile belirli bir adet döngüsü evresi arasında ilişki olup olmadığı sorusu ortaya atılmıştır, ancak konu ile ilgili veriler kısıtlıdır ve tutarlı değildir. Sonuç: Az sayıda çalışma bu ilişkiyi açıklamaya çalışmış, çoğunda belirtiler ileriye dönük değerlendirilmemiştir; çoğu, az sayıda hasta içermektedir ve adet döngüsünün evresini belirlemek için güvenilir inceleme yöntemleri kullanılmamıştır. Ek olarak, pekçok çalışmada adet öncesi (premenstrüel) kötüleşmenin altta yatan hastalığın alevlenmesini mi, yoksa sadece adet döngüsünün belirli bir evresinde ortaya çıkan yeni belirtileri mi yansıttığı belirlenmemiştir. Gelecek çalışmalarda ruhsal hastalığın adet öncesi dalgalanmasının anlamı veya duygudurum bozukluğunun hastalık şiddetini artırması ve sağaltıma direnci ile ilgili bilgilere daha çok yer verilmelidir.
Fen > Tıp > Psikiyatri
DergiDerlemeErişime Açık
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