Objectives: To investigate whether any relationship exists between traumatic perforations of the tympanic membrane and aeration of the temporal bone cells. Patients and Methods: Twenty-five male patients (age range 17-32 years, mean age 24.5 years) with tympanic membrane perforations resulting from blast injury, slap, or football hit were included. A control group of 20 healthy male volunteers was formed. Temporal bone computed tomographic scans were obtained in axial plane, parallel to the infraorbitomeatal line using 2 mm slice thickness and 2 mm intervals. To calculate the volume of each slice, the area of air cells was measured and multiplied by the slice thickness. Volumes of slices containing air cells were added to obtain the volume of each ear. Twenty patients had patch treatment and five patients underwent tympanoplasty operation. Preoperative and postoperative odiologic examinations were made. Results: Perforations were found to be frequently located in the lower quadrants, most of them being less than 3 mm. There were no perforations in the region of pars flaccida or marginal perforations. Hearing levels were within normal range except those who were exposed to blast injury. Neither temporal bone tomography nor intraoperative examinations showed ossicular chain destruction. No statistically significant differences were found between the mean volumes of right and left ear temporal bone air cells in the patient and control groups. Conclusion: It was found that the level of temporal bone aeration has no statistically significant effect on tympanic membrane pathologies due to blast or other injuries.