PURPOSE: PMS is a complex of syndromes, occuring in the second half of the menstruel cycle and disappearing by themselves with the beginning of menstruel bleeding, preventing daily activity and need to the treatment. The aim of this study was to determine the prevalance of PMS, family history and applyed to a health center with this symptoms of PMS in girl students in Ondokuzmayıs University. MATERIAL AND METHOD: A questionnaire about PMS was applied 397 first year girl students face to face selected in eight faculties of Ondokuzmayıs University on October 1997 and results were evaluated with chi-square statistical analysis metod by using Epi Info 6 statistical analyse programe. RESULTS: The prevalence of PMS was found 58.2 % in this study. Family history was positive in 158(68.4%) and 83(50.0%) of participants with PMS and without PMS, respectively and there was a statistically significant difference between them (p<0.001, X:=18.75). 57(24.7%) of girls with PMS need to apply to a health center, 21 (12.7%) of girls without PMS need to apply to a health center with various complaints during menstruel cycle and there was a statistically significant difference between them (p<0.05, X =6.04). CONCLUSION: Because of the prevalence found in this study is higher than the other studies, it is thought that this subject should be examined carefully.