Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?

GÖZLÜKAYA, Fatma; ESEN, Hasan; BÜYÜKYAZI, Gürbüz; Ulman, Cevval; TIKIZ, Hakan; TANELİ, FATMA; ARI, Zeki

Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?

Hasan ESEN, (Celal Bayar Üniversitesi, Beden Eğitimi ve Spor Yüksek Okulu, Manisa, Türkiye)

Gürbüz BÜYÜKYAZI, (Celal Bayar Üniversitesi, Beden Eğitimi ve Spor Yüksek Okulu, Manisa, Türkiye)

Cevval ULMAN, (Celal Bayar Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Manisa, Türkiye)

Fatma TANELİ, (Celal Bayar Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Manisa, Türkiye)

Zeki ARI, (Celal Bayar Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Manisa, Türkiye)

Fatma GÖZLÜKAYA, (Celal Bayar Üniversitesi, Beden Eğitimi ve Spor Yüksek Okulu, Manisa, Türkiye)

Hakan TIKIZ (Celal Bayar Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Manisa, Türkiye)

Türk Biyokimya Dergisi

6 1

Yıl: 2009 Cilt: 34 Sayı: 3 Sayfa Aralığı: 178 - 186 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?

Öz:

Amaç: On haftalık yürüyüş programlarının maksimal oksijen tüketimi, vücut kompozisyonu, serum lipidleri, yüksek sensitiviteli C-reaktif protein, osteoprotegerin ve soluble reseptör aktivatör nükleer faktör-kappaβ ligandı üzerine etkilerini incelemek.Yöntem: Yirmi yedi orta yaşlı (40-60yaş) erkek on hafta, haftada beş gün, günde 40-52dakika orta veya yüksek şiddette (sırasıyla ~5.95±0.26km/s ve ~7.64±0.36km/s; maksimum kalp atım hızı rezervinin %50-55 ve %70-75’inde) yürüdüler. Yürüyüş yapmayanlarkontrol grubunu oluşturdu (n=13). Egzersiz programı öncesi ve sonrasında, tahmini maksimal oksijen tüketimi, vücut kompozisyonu, lipid profili, yüksek sensitiviteli C-reaktifprotein, osteoprotegerin ve soluble reseptör aktivatör nükleer faktör-kappaβ ligandı düzeyleri belirlendi.Bulgular: On haftanın sonunda tahmini maksimal oksijen tüketimi yüksek-şiddet grubunun lehine (p<.05) her iki egzersiz grubunda arttı (p<.05). Vücut ağırlığı, vücut yağ yüzdesi ve beden kitle indeksi değerlerinde egzersiz gruplarında anlamlı azalmalar meydana geldi (p<.05). Yürüyüş antrenmanları kan lipit değerleri, yüksek sensitiviteli C-reaktifprotein ve osteoprotegerin düzeyleri üzerinde etkili bulunmadı, ancak soluble reseptöraktivatör nükleer faktör-kappaβ ligand yüksek şiddet grubunda anlamlı olarak azaldı(p<.05); egzersiz gruplarında belirlenen değişim kontrol grubundaki değişimden farklıydı (p<.05). Sonuç: Soluble reseptör aktivatör nükleer faktör-kappaβ ligand ve tahmini maksimal oksijen tüketiminde meydana gelen gelişmelerden dolayı kardiyak risk faktörlerine ve damarsal kalsifikasyona karşı koruyucu etkiler yaratabilmek için yüksek şiddet yürümeprogramları önerilebilir.

Anahtar Kelime:

Konular: Biyokimya ve Moleküler Biyoloji

Yürüyüş programları C-reaktif protein, osteoprotegerin ve soluble reseptör aktivatör nükleer faktör-kappaβ ligand düzeylerini etkiler mi?

Öz:

Aim: To examine the effects of 10-week walking programs on maximal oxygen consumption, body composition, serum lipids, highly-sensitive C-reactive protein, osteoprotegerinand soluble receptor activator of nuclear factor-kappaβ ligand.Method: Twenty-seven middle-aged men (40-60years) walked for ten weeks, five daysper week, 40-52min per day at either moderate or high intensity (~5.95±0.26km/h and~7.64±0.36km/h; 50-55% and 70-75% maximum heart rate reserve, respectively). Nonwalking, sedentary men served as controls (n=13). Estimated maximal oxygen consumption, body composition, lipid profile, highly-sensitive C-reactive protein, osteoprotegerinand soluble receptor activator of nuclear factor-kappaβ ligand were determined before andafter the study.Results: After 10 weeks, estimated maximal oxygen consumption improved in both exercise groups (p<.05), favoring high-intensity group (p<.05). Body weight, percent bodyfat, and body mass index reduced significantly in both exercise groups (p<.05). Walking programs did not cause any significant changes in blood lipids, highly-sensitive Creactive protein, and osteoprotegerin levels; however, soluble receptor activator of nuclearfactor-kappaβ ligand levels were found to decrease in high-intensity group (p<.05) and thechange observed in both exercise groups was different from the change in control group(p<.05).Conclusion: For protective effects against cardiac risk factors and arterial calcification,high-intensity walking programs are advisable due to the greater improvements in solublereceptor activator of nuclear factor-kappaβ ligand and estimated maximal oxygen consumption.

Anahtar Kelime:

Konular: Biyokimya ve Moleküler Biyoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ESEN H, BÜYÜKYAZI G, Ulman C, TANELİ F, ARI Z, GÖZLÜKAYA F, TIKIZ H (2009). Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. , 178 - 186.
Chicago	ESEN Hasan,BÜYÜKYAZI Gürbüz,Ulman Cevval,TANELİ FATMA,ARI Zeki,GÖZLÜKAYA Fatma,TIKIZ Hakan Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. (2009): 178 - 186.
MLA	ESEN Hasan,BÜYÜKYAZI Gürbüz,Ulman Cevval,TANELİ FATMA,ARI Zeki,GÖZLÜKAYA Fatma,TIKIZ Hakan Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. , 2009, ss.178 - 186.
AMA	ESEN H,BÜYÜKYAZI G,Ulman C,TANELİ F,ARI Z,GÖZLÜKAYA F,TIKIZ H Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. . 2009; 178 - 186.
Vancouver	ESEN H,BÜYÜKYAZI G,Ulman C,TANELİ F,ARI Z,GÖZLÜKAYA F,TIKIZ H Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. . 2009; 178 - 186.
IEEE	ESEN H,BÜYÜKYAZI G,Ulman C,TANELİ F,ARI Z,GÖZLÜKAYA F,TIKIZ H "Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?." , ss.178 - 186, 2009.
ISNAD	ESEN, Hasan vd. "Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?". (2009), 178-186.

APA	ESEN H, BÜYÜKYAZI G, Ulman C, TANELİ F, ARI Z, GÖZLÜKAYA F, TIKIZ H (2009). Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. Türk Biyokimya Dergisi, 34(3), 178 - 186.
Chicago	ESEN Hasan,BÜYÜKYAZI Gürbüz,Ulman Cevval,TANELİ FATMA,ARI Zeki,GÖZLÜKAYA Fatma,TIKIZ Hakan Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. Türk Biyokimya Dergisi 34, no.3 (2009): 178 - 186.
MLA	ESEN Hasan,BÜYÜKYAZI Gürbüz,Ulman Cevval,TANELİ FATMA,ARI Zeki,GÖZLÜKAYA Fatma,TIKIZ Hakan Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. Türk Biyokimya Dergisi, vol.34, no.3, 2009, ss.178 - 186.
AMA	ESEN H,BÜYÜKYAZI G,Ulman C,TANELİ F,ARI Z,GÖZLÜKAYA F,TIKIZ H Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. Türk Biyokimya Dergisi. 2009; 34(3): 178 - 186.
Vancouver	ESEN H,BÜYÜKYAZI G,Ulman C,TANELİ F,ARI Z,GÖZLÜKAYA F,TIKIZ H Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?. Türk Biyokimya Dergisi. 2009; 34(3): 178 - 186.
IEEE	ESEN H,BÜYÜKYAZI G,Ulman C,TANELİ F,ARI Z,GÖZLÜKAYA F,TIKIZ H "Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?." Türk Biyokimya Dergisi, 34, ss.178 - 186, 2009.
ISNAD	ESEN, Hasan vd. "Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?". Türk Biyokimya Dergisi 34/3 (2009), 178-186.