The association between C-reactive protein and metabolic syndrome components

KURAL, Alev; Yigit, Namik; KOLDAŞ, Mcit; Omma, Ahmet; SEVAL, Hatice

The association between C-reactive protein and metabolic syndrome components

Alev KURAL, (SB Haseki Eğitim ve Araştırma Hastanesi, İstanbul, Türkiye)

Mcit KOLDAŞ, (SB Haseki Eğitim ve Araştırma Hastanesi, İstanbul, Türkiye)

Hatice SEVAL, (SB Haseki Eğitim ve Araştırma Hastanesi, İstanbul, Türkiye)

Ahmet OMMA, (SB Haseki Eğitim ve Araştırma Hastanesi, İstanbul, Türkiye)

Namık YİĞİT (SB Haseki Eğitim ve Araştırma Hastanesi, İstanbul, Türkiye)

İnönü Üniversitesi Tıp Fakültesi Dergisi

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Yıl: 2007 Cilt: 14 Sayı: 3 Sayfa Aralığı: 145 - 148 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The association between C-reactive protein and metabolic syndrome components

Öz:

Giriş: İnsülin direnci metabolik sendrom ile ilişkilidir ve kardiyovasküler hastalıklar için risk faktörüdür. C-Reaktif protein (CRP) gelecekteki kardiyovasküler hastalıkların habercisi olan bir proinflamatuar belirteçdir. Biz bu çalışmada insülin direnci ile CRP düzeylerinin ilişkisini ve CRP’nin metabolik sendromda kriter olup olmayacağını araştırdık.Gereç ve Yöntem: Bu çalışmaya metabolik sendrom tanısı almış 63 hasta ile 20 sağlıklı kontrol grubu dahil edildi. Açlık kan glukoz seviyeleri, insülin ve CRP düzeyleri ölçüldü. İnsülin dirençleri (Homeostasis Model Assessment=HOMA-IR) formülü kullanılarak değerlendirildi.Bulgular: Metabolik sendromlu hasta grubu ile kontrol grubu arasında bel çevresi, açlık glukozu, insülin ve CRP değerleri arasında istatistiksel anlamlı farklılıklar vardı. Hasta grubunda açlık glukoz düzeyleri ve CRP arasında (P=0,0001, r=0,3) ve HOMA-IR ile CRP arasında (P=0,007, r=0,29) zayıf fakat anlamlı bir ilişki vardı.Sonuç: CRP’nin metabolik sendromun tanı ve takibinde önemli bir parametre olduğu sonucuna vardık.

Anahtar Kelime: C-reaktif protein Metabolik sendrom X Bel çevresi İnsülin direnci

Konular: Genel ve Dahili Tıp

CRP ile metabolik sendrom arasındaki ilişki

Öz:

Background: Insulin resistance is associated with metabolic syndrome and is a risk factor for cardiovascular disease. C-reactive protein (CRP) is an inflammatory marker which is demonstrated as a strong predictor of future cardiovascular events.Material Method: In this study, sixty-three patients who were diagnosed with metabolic syndrome and twenty healthy controls were recruited. Fasting blood glucose, insulin and CRP levels were measured. Homeostasis Model Assessment (HOMA-IR) formula is used to evaluate insulin resistance. We investigated the relationship between insulin resistance and CRP levels and whether CRP is a metabolic syndrome criterion or not.Results: There were statistically significant differences between patients with metabolic syndrome and controls in terms of waist circumference, fasting glucose, insulin and CRP levels. In patients, we found a poor but significant relationship between fasting glucose levels and CRP (P=0.0001, r=0.3) and between HOMA-IR values and CRP (P=0.007, r=0.29).Conclusion: We concluded that CRP may have an important role in the diagnosis and follow-up of metabolic syndrome.

Anahtar Kelime: C-Reactive Protein Metabolic Syndrome X Waist Circumference Insulin Resistance

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	KURAL A, KOLDAŞ M, SEVAL H, Omma A, Yigit N (2007). The association between C-reactive protein and metabolic syndrome components. , 145 - 148.
Chicago	KURAL Alev,KOLDAŞ Mcit,SEVAL Hatice,Omma Ahmet,Yigit Namik The association between C-reactive protein and metabolic syndrome components. (2007): 145 - 148.
MLA	KURAL Alev,KOLDAŞ Mcit,SEVAL Hatice,Omma Ahmet,Yigit Namik The association between C-reactive protein and metabolic syndrome components. , 2007, ss.145 - 148.
AMA	KURAL A,KOLDAŞ M,SEVAL H,Omma A,Yigit N The association between C-reactive protein and metabolic syndrome components. . 2007; 145 - 148.
Vancouver	KURAL A,KOLDAŞ M,SEVAL H,Omma A,Yigit N The association between C-reactive protein and metabolic syndrome components. . 2007; 145 - 148.
IEEE	KURAL A,KOLDAŞ M,SEVAL H,Omma A,Yigit N "The association between C-reactive protein and metabolic syndrome components." , ss.145 - 148, 2007.
ISNAD	KURAL, Alev vd. "The association between C-reactive protein and metabolic syndrome components". (2007), 145-148.

APA	KURAL A, KOLDAŞ M, SEVAL H, Omma A, Yigit N (2007). The association between C-reactive protein and metabolic syndrome components. İnönü Üniversitesi Tıp Fakültesi Dergisi, 14(3), 145 - 148.
Chicago	KURAL Alev,KOLDAŞ Mcit,SEVAL Hatice,Omma Ahmet,Yigit Namik The association between C-reactive protein and metabolic syndrome components. İnönü Üniversitesi Tıp Fakültesi Dergisi 14, no.3 (2007): 145 - 148.
MLA	KURAL Alev,KOLDAŞ Mcit,SEVAL Hatice,Omma Ahmet,Yigit Namik The association between C-reactive protein and metabolic syndrome components. İnönü Üniversitesi Tıp Fakültesi Dergisi, vol.14, no.3, 2007, ss.145 - 148.
AMA	KURAL A,KOLDAŞ M,SEVAL H,Omma A,Yigit N The association between C-reactive protein and metabolic syndrome components. İnönü Üniversitesi Tıp Fakültesi Dergisi. 2007; 14(3): 145 - 148.
Vancouver	KURAL A,KOLDAŞ M,SEVAL H,Omma A,Yigit N The association between C-reactive protein and metabolic syndrome components. İnönü Üniversitesi Tıp Fakültesi Dergisi. 2007; 14(3): 145 - 148.
IEEE	KURAL A,KOLDAŞ M,SEVAL H,Omma A,Yigit N "The association between C-reactive protein and metabolic syndrome components." İnönü Üniversitesi Tıp Fakültesi Dergisi, 14, ss.145 - 148, 2007.
ISNAD	KURAL, Alev vd. "The association between C-reactive protein and metabolic syndrome components". İnönü Üniversitesi Tıp Fakültesi Dergisi 14/3 (2007), 145-148.