Yıl: 2010 Cilt: 23 Sayı: 1 Sayfa Aralığı: 14 - 21 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy

Öz:
Amaç: Bu çalışmada, hasta kontrollü analjezi yöntemi ile uygulanan tramadolün supratentoriyal kraniyotomi sonrası ağrı tedavisinde etkinliğinin araştırılması amaçlanmıştır.Gereç ve Yöntem: Elektif supratentoriyal kraniyotomi operasyonu planlanan, ASA I-II grubundan, 18-70 yaş arasında 150 hasta çalışmaya dahil edilerek, propofol ve remifentanil ile standart genel anestezi uygulandı. Bupivakain ve epinefrin ile çivili başlık noktalarına ve cerrahi insizyona skalp infiltrasyonu uygulandı. Hastalar tam olarak uyandıktan sonra ekstübe edilerek, postoperatif ağrı skorları, vizüel analog skalası (VAS) skoru kullanılarak değerlendirildi. VAS skoru >3 olduğunda, tramadol 1-1.5 mg/kg titre edilerek intravenöz olarak uygulandı ve intravenöz hasta kontrollü analjezi yöntemi ile tramadol (20 mg bolus ve 8 dakika kilitli kalma süresi) uygulanmaya başlandı. Postoperatif 48 saat süresince VAS, Glasgow koma, sedasyon, konfor, bulantı ve kusma skorları takip edildi.Bulgular: Postoperatif 48 saat süresince hastaların %46`sının analjezik ihtiyacı oldu ve bu hastalarda intravenöz hasta kontrollü analjezi yöntemi ile uygulanan tramadol ile yeterli analjezi sağladı. Postoperatif ilk 2 saatte analjezik ihtiyacının daha yüksek olduğu belirlendi (p<0.05).Sonuç: İntravenöz hasta kontrollü analjezi yöntemi ile uygulanan tramadolün kraniyotomi operasyonu sonrası ağrı tedavisinde etkin olduğu sonucuna varılmıştır.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Hasta kontrollü analjezi yöntemi ile uygulanan tramadolün supratentoriyal kraniyotomi sonrası ağrı tedavisinde etkinliğinin araştırılması

Öz:
Objective: The aim of this study was to evaluate the analgesic efficacy of intravenous PCA using tramadol in patients, undergoing supratentorial tumor resection with craniotomy.Material and Method: One hundred and fifty patients with ASA I-II between 18 and 70 years of age scheduled for an elective supratentorial craniotomy for tumor resection, were assigned to receive standardized general anesthesia. Postoperative pain was assessed at standard time intervals using a visual analogue scale (VAS) score. When the VAS score was >3, 1 to 1.5 mg/kg of tramadol was administered intravenously and PCA using tramadol was started. For 48 h postoperatively, the VAS, Glasgow coma, sedation, comfort, and nausea and vomiting scores were assessed.Results: During the first 48 hours, 46% of the patients needed analgesic therapy and PCA with tramadol was adequate for these patients. Most patients needed analgesic drugs at 2 hours and their mean analgesic usage was higher at that point than at other periods in the first 2 h (p<0.05).Conclusion: PCA with tramadol can be used effectively for postoperative pain management after craniotomy.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1) Gottschalk A, Berkow LC, Stevens RD, et al. Prospective evaluation of pain and analgesic use following major elective intracranial surgery. J Neurosurg 2007; 106:210–216.
  • 2) Roberts GC. Post-craniotomy analgesia: current practices in British neurosurgical centres--a survey of post-craniotomy analgesic practices. Eur J Anaesthesiol 2005; 22: 328-332.
  • 3) Stoneham MD, Walters FJ. Post-operative analgesia for craniotomy patients: current attitudes among neuroanaesthetists. Eur J Anaesthesiol 1995;12:571-575.
  • 4) Quiney N, Cooper R, Stoneham M, Walters F. Pain after craniotomy. A time for reappraisal? Br J Neurosurg 1996;10:295-299.
  • 5) Jeffrey HM, Charlton P, Mellor DJ, Moss E, Vucevic M. Analgesia after intracranial surgery: A double-blind, prospective comparison of codeine and tramadol. Br J Anaesth 1999;83:245-249.
  • 6) Palmer JD, Sparrow OC, Ianotti F. Postoperative haematoma: a five-year survey and identification of avoidable risk factors. Neurosurgery 1994;35:1061-1065.
  • 7) Bloomfield EL, Schubert A, Secic M, Barnett G, Shutway F, Ebrahim ZY. The influence of scalp infiltration with bupivacaine on hemodynamics and postoperative pain in adult patients undergoing craniotomy. Anesth Analg 1998;87:579-582.
  • 8) Lehmann KA. Tramadol in acute pain. Drugs 53 Suppl 1997;2:25-33.
  • 9) Lee CR, McTavish D, Sorkin EM. Tramadol: A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states. Drugs 1993; 46:313–340.
  • 10) Coetzee JF, van Loggerenberg H: Tramadol or morphine administered during operation: A study of immediate postoperative effects after abdominal hysterectomy. Br J Anaesth 1998; 81:737–741.
  • 11) Houmes RJ, Voets MA, Verkaaik A, et al. Efficacy and safety of tramadol versus morphine for moderate and severe postoperative pain with special regard to respiratory depression. Anesth Analg 1992;74:510–514.
  • 12) Vickers MD, Paravicini D. Comparison of tramadol with morphine for post-operative pain following abdominal surgery. Eur J Anesthesiol 1995;12:265-271.
  • 13) Bono AV, Cuffari S. Effectiveness and tolerance of tramadol in cancer pain. A comparative study with respect to buprenorphine. Drugs 1997;53:40-49.
  • 14) Derrode N, Lebrun F, Levron JC, Chauvin M, Debaene B. Influence of perioperative opioid on postoperative pain after major abdominal surgery: Sufentanil TCI versus remifentanil TCI. A randomized, controlled study. Br J Anaesth 2003; 91:842-849.
  • 15) Gerlach K, Uhlig T, Huppe M, et al. Remifentanil-propofol versus sufentanil-propofol anaesthesia for supratentorial craniotomy: A randomized trial. Eur J Anaesthesiol 2003;20:813-820.
  • 16) Guignard B, Bossars A, Coste C, et al. Acute opioid tolerance. Intraoperative remifentanil increases postoperative pain and morphine requirement. Anesthesiology 2000; 93:409–417.
  • 17) Verchere E, Grenier B, Mesli A, Siao D, Sesay M, Maurette P. Postoperative pain management after supratentorial craniotomy. J Neurosurg Anesthesiol 2002;14:96-101.
  • 18) Vickers MD, O`Flaherty D, Szekely SM, Read M, Yoshizumi IJ: Tramadol: Pain relief by an opioid without depression of respiration. Anaesthesia 1992;47:291-296.
  • 19) Sudheer PS, Logan SW, Terblanche C, Ateleanu B, Hall JE. Comparison of the analgesic efficacy and respiratory effects of morphine, tramadol and codeine after craniotomy. Anaesthesia 2007;62:555–560.
  • 20) Biswas BK, Bithal PK. Preincision 0.25% bupivacaine scalp infiltration and postcraniotomy pain: A randomized double-blind, placebo-controlled study. J Neurosurg Anesthesiol 2003;15:234-239.
  • 21) Nguyen A, Girard F, Boudreault D, et al. Scalp nerve blocks decrease the severity of pain after craniotomy. Anesth Analg 2001;93:1272-1276.
  • 22) Naguib M, Seraj M, Attia M, Samarkandi AH, Seet M, Jaroudi R. Perioperative antinociceptive effects of tramadol. A prospective, randomized, double-blind comparison with morphine. Can J Anaesth1998;45:1168–1175. Thibault M, Girard F, Moumdjian R, Chouinard P, Boudreault D, Ruel M. Craniotomy site influences postoperative pain following neurosurgical procedures: a retrospective study. Can J Anaesth 2007;54:544-548.
APA TÜR H, KARACALAR S, UTANIR ALTAY S, SARIHASAN B, TÜRE U, ÇELİK F, TÜR A (2010). The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. , 14 - 21.
Chicago TÜR Hatice,KARACALAR Serap,UTANIR ALTAY Sinem,SARIHASAN Binnur,TÜRE Uğur,ÇELİK Fahrettin,TÜR Ayla The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. (2010): 14 - 21.
MLA TÜR Hatice,KARACALAR Serap,UTANIR ALTAY Sinem,SARIHASAN Binnur,TÜRE Uğur,ÇELİK Fahrettin,TÜR Ayla The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. , 2010, ss.14 - 21.
AMA TÜR H,KARACALAR S,UTANIR ALTAY S,SARIHASAN B,TÜRE U,ÇELİK F,TÜR A The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. . 2010; 14 - 21.
Vancouver TÜR H,KARACALAR S,UTANIR ALTAY S,SARIHASAN B,TÜRE U,ÇELİK F,TÜR A The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. . 2010; 14 - 21.
IEEE TÜR H,KARACALAR S,UTANIR ALTAY S,SARIHASAN B,TÜRE U,ÇELİK F,TÜR A "The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy." , ss.14 - 21, 2010.
ISNAD TÜR, Hatice vd. "The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy". (2010), 14-21.
APA TÜR H, KARACALAR S, UTANIR ALTAY S, SARIHASAN B, TÜRE U, ÇELİK F, TÜR A (2010). The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. Marmara Medical Journal, 23(1), 14 - 21.
Chicago TÜR Hatice,KARACALAR Serap,UTANIR ALTAY Sinem,SARIHASAN Binnur,TÜRE Uğur,ÇELİK Fahrettin,TÜR Ayla The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. Marmara Medical Journal 23, no.1 (2010): 14 - 21.
MLA TÜR Hatice,KARACALAR Serap,UTANIR ALTAY Sinem,SARIHASAN Binnur,TÜRE Uğur,ÇELİK Fahrettin,TÜR Ayla The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. Marmara Medical Journal, vol.23, no.1, 2010, ss.14 - 21.
AMA TÜR H,KARACALAR S,UTANIR ALTAY S,SARIHASAN B,TÜRE U,ÇELİK F,TÜR A The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. Marmara Medical Journal. 2010; 23(1): 14 - 21.
Vancouver TÜR H,KARACALAR S,UTANIR ALTAY S,SARIHASAN B,TÜRE U,ÇELİK F,TÜR A The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy. Marmara Medical Journal. 2010; 23(1): 14 - 21.
IEEE TÜR H,KARACALAR S,UTANIR ALTAY S,SARIHASAN B,TÜRE U,ÇELİK F,TÜR A "The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy." Marmara Medical Journal, 23, ss.14 - 21, 2010.
ISNAD TÜR, Hatice vd. "The efficacy of intravenous patient-controlled analgesia using tramadol following supratentorial tumor resection craniotomy". Marmara Medical Journal 23/1 (2010), 14-21.