Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats

DURU, OZKAN; BAŞALAN, MEHMET; YILDIZ, Kader; GOKPINAR, Sami

Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats

Kader YILDIZ, (Kırıkkale Üniversitesi, Veteriner Fakültesi, Parazitoloji Anabilim Dalı, Kırıkkale, Türkiye)

Mehmet BAŞALAN, (Kırıkkale Üniversitesi Veteriner Fakültesi, Hayvan Besleme ve Beslenme Hastalıkları Anabilim Dalı, Kırıkkale, Türkiyr)

Özkan DURU, (Kırıkkale Üniversitesi, Veteriner Fakültesi, Biyokimya Anabilim Dalı, Kırıkkale, Türkiye)

Sami GÖKPINAR (Kırıkkale Üniversitesi, Veteriner Fakültesi, Parazitoloji Anabilim Dalı, Kırıkkale, Türkiye)

Türkiye Parazitoloji Dergisi

5 1

Yıl: 2011 Cilt: 35 Sayı: 1 Sayfa Aralığı: 10 - 14 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats

Öz:

Amaç: Bu çalışmada Toxocara cati ile doğal enfekte kedilere Artemisia absinthum ekstresinin etkinliğini ile in vitro ortamda T.cati yumurtasındaki embriyonik gelişime etkisinin belirlenmesi amaçlanmıştır. Yöntemler: Artemisia absinthum ekstresi kedilere 300 mg/kg (Grup 1) ve 600 mg/kg (Grup 2) dozda ağızdan verilmiştir. Ekstre günde bir kez olacak biçimde 7 gün süreyle uygulanmıştır. Kedilerin dışkıları tedavi öncesinde, tedavi esnasında ve tedavi sonrasında makroskobik ve doymuş tuzlu su fl otasyon yöntemi ile mikroskobik olarak incelenmiştir. Ekstre verilmesi bittikten sonraki 8 gün süreyle dışkı incelenmiştir. Dışkı yumurta sayısındaki değişim McMaster tekniği kullanılarak belirlenmiştir. Bulgular: Deneme gruplarındaki kedilerde gram dışkıdaki yumurta sayısının dereceli olarak azaldığı gözlenmiştir. Tedavi esnasında kedilerde ALT, AST, ALP, üre ve kreatinin aktivitelerinin fi zyolojik değerler arasında olduğu belirlenmiştir. A.abstinhum ile yapılan in vitro denemelerde tüm gruplarda (tedavi ve kontrol) T.cati yumurtaları içindeki embriyonik gelişimin benzer olduğu gözlenmiştir. A.absinthum ekstresi in vitro ortamda larva gelişimini engellemediği belirlenmiştir. Sonuç: Bu bitki ekstresi gelecekte parazit hastalıkalrının tedavisi için bir alternatif olabilir.

Anahtar Kelime: Kedi hastalıkları Artemisia absinthium Antiparaziter ajanlar Bitki ekstreleri Kediler Toxocara

Konular: Genel ve Dahili Tıp Parazitoloji

Doğal enfekte kedilerde Toxocara cati’ye Artemisia absinthium’un etkisi

Öz:

Objective: The fi rst aim of the present study was to determine the effi ciency of A. absinthium extract on cats naturally infected with Toxocara cati. The second aim was to determine the effi ciency of the extract on the embryonic development of T. cati eggs in vitro. Methods: Artemisia absinthium extract was orally administrated to cats at the doses of 300 mg/kg and 600 mg/kg body weight in Group 1 and 2, respectively. It was given only once a day and the treatment continued 7 consecutive days. The faeces of the cats were examined both macroscopically and microscopically by fl otation procedure with saturated salt solution pre-, during and post- treatment period. The faecal analysis was maintained during 8 days after completing the extract administration. The alteration of faecal egg numbers was performed by using the McMaster technique. Results: The faecal egg numbers per gram were decreased gradually in cats in the trial groups. In the treatment period, the activities of ALT, AST, ALP, urea and creatinine were located within the physiological ranges in cats. In in vitro trials with A. absinthium extract, the embryonic development of T. cati eggs was identical in all groups (treatment and control). A. absinthium extract did not inhibit larval development in eggs in in vitro trials. Conclusion: This plant extract may be an alternative choice in the treatment of parasitic diseases in future.

Anahtar Kelime: Plant Extracts Cats Toxocara Cat Diseases Artemisia absinthium Antiparasitic Agents

Konular: Genel ve Dahili Tıp Parazitoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	YILDIZ K, BAŞALAN M, DURU O, GOKPINAR S (2011). Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. , 10 - 14.
Chicago	YILDIZ Kader,BAŞALAN MEHMET,DURU OZKAN,GOKPINAR Sami Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. (2011): 10 - 14.
MLA	YILDIZ Kader,BAŞALAN MEHMET,DURU OZKAN,GOKPINAR Sami Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. , 2011, ss.10 - 14.
AMA	YILDIZ K,BAŞALAN M,DURU O,GOKPINAR S Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. . 2011; 10 - 14.
Vancouver	YILDIZ K,BAŞALAN M,DURU O,GOKPINAR S Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. . 2011; 10 - 14.
IEEE	YILDIZ K,BAŞALAN M,DURU O,GOKPINAR S "Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats." , ss.10 - 14, 2011.
ISNAD	YILDIZ, Kader vd. "Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats". (2011), 10-14.

APA	YILDIZ K, BAŞALAN M, DURU O, GOKPINAR S (2011). Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. Türkiye Parazitoloji Dergisi, 35(1), 10 - 14.
Chicago	YILDIZ Kader,BAŞALAN MEHMET,DURU OZKAN,GOKPINAR Sami Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. Türkiye Parazitoloji Dergisi 35, no.1 (2011): 10 - 14.
MLA	YILDIZ Kader,BAŞALAN MEHMET,DURU OZKAN,GOKPINAR Sami Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. Türkiye Parazitoloji Dergisi, vol.35, no.1, 2011, ss.10 - 14.
AMA	YILDIZ K,BAŞALAN M,DURU O,GOKPINAR S Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. Türkiye Parazitoloji Dergisi. 2011; 35(1): 10 - 14.
Vancouver	YILDIZ K,BAŞALAN M,DURU O,GOKPINAR S Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats. Türkiye Parazitoloji Dergisi. 2011; 35(1): 10 - 14.
IEEE	YILDIZ K,BAŞALAN M,DURU O,GOKPINAR S "Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats." Türkiye Parazitoloji Dergisi, 35, ss.10 - 14, 2011.
ISNAD	YILDIZ, Kader vd. "Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats". Türkiye Parazitoloji Dergisi 35/1 (2011), 10-14.