Panic provocation studies with placebo

LEVINE, Louise R.; POTTER, William Z.; ÖZCAN, M. Erkan

Panic provocation studies with placebo

M. Erkan ÖZCAN, (İnönü Üniversitesi, Tıp Fakültesi, Psikiyatri Anabilim Dalı, Malatya, Türkiye)

Louise R. LEVINE, (Girilmedi)

William Z. POTTER (Girilmedi)

Klinik Psikofarmakoloji Bülteni

3 0

Yıl: 2000 Cilt: 10 Sayı: 1 Sayfa Aralığı: 38 - 42 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Panic provocation studies with placebo

Öz:

Amaç: Bu makalede, panik bozukluğu olan hastalarla ya da sağlıklı bireylerle, plasebo kontrollü olarak yapılmış olan panik provokasyonu çalışmaları gözden geçirilmiştir. Yöntem: İngilizce yazılmış dergiler ve medline taranarak konu ile ilgili makalelere ulaşılmış ve bu çalışmalarda elde edilen sonuçlar derlenmiştir.Bulgular: Sodyum laktat, kolesistokinin ve karbondioksit panik provokasyonu amacı ile en çok kullanılan maddelerdir. Bu maddelere genel olarak bakıldığında duyarlı, güvenli ve güvenilir görünmektedirler.Sonuçlar: Bu çalışmalarda elde edilen bulgular, panik provokasyon testlerinin, hem halen anksiyete bozukluklarının dışındaki endikasyonlarda kullanılmakta olan ilaçların, hem de yeni bulunacak ilaçların anksiyete bozukluklarındaki etkinliğini ölçebileceğini göstermektedir. Panik provokasyonu çalışmaları, anksiyete bozukluklarının oluş mekanizmalarının daha iyi anlaşılmasına katkıda bulunabilirler.

Anahtar Kelime: İlaç değerlendirmesi Panik bozukluğu Karbon dioksit Kolesistokinin Sodyum laktat Kaygı bozuklukları Plasebo Provokatif testler

Konular: Farmakoloji ve Eczacılık

Plasebo kontrollü panik provokasyonu çalışmaları

Öz:

Objective: We intended to review studies investigating panic provocation tests using placebo and active drugs in panic disorder patients or in healthy controls. Method: A manual and computerized (MEDLINE) search was performed to examine the English-language literature on panic provocation studies. Results: Sodium lactate, cholecystokinin and carbon dioxide challenge tests are the most frequently used tools. These challenge tests generally seem sensitive, safe, and reliable. Conclussions: The results of these tests may or may not prove the efficacy of both novel compounds and drugs already marketed for indications other than anxiety disorders. Panic provocation studies may contribute to our understanding of anxiety disorders.

Anahtar Kelime: Placebos Provocative tests Drug Evaluation Panic Disorder Carbon Dioxide Cholecystokinin Sodium Lactate Anxiety Disorders

Konular: Farmakoloji ve Eczacılık

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ÖZCAN M, LEVINE L, POTTER W (2000). Panic provocation studies with placebo. , 38 - 42.
Chicago	ÖZCAN M. Erkan,LEVINE Louise R.,POTTER William Z. Panic provocation studies with placebo. (2000): 38 - 42.
MLA	ÖZCAN M. Erkan,LEVINE Louise R.,POTTER William Z. Panic provocation studies with placebo. , 2000, ss.38 - 42.
AMA	ÖZCAN M,LEVINE L,POTTER W Panic provocation studies with placebo. . 2000; 38 - 42.
Vancouver	ÖZCAN M,LEVINE L,POTTER W Panic provocation studies with placebo. . 2000; 38 - 42.
IEEE	ÖZCAN M,LEVINE L,POTTER W "Panic provocation studies with placebo." , ss.38 - 42, 2000.
ISNAD	ÖZCAN, M. Erkan vd. "Panic provocation studies with placebo". (2000), 38-42.

APA	ÖZCAN M, LEVINE L, POTTER W (2000). Panic provocation studies with placebo. Klinik Psikofarmakoloji Bülteni, 10(1), 38 - 42.
Chicago	ÖZCAN M. Erkan,LEVINE Louise R.,POTTER William Z. Panic provocation studies with placebo. Klinik Psikofarmakoloji Bülteni 10, no.1 (2000): 38 - 42.
MLA	ÖZCAN M. Erkan,LEVINE Louise R.,POTTER William Z. Panic provocation studies with placebo. Klinik Psikofarmakoloji Bülteni, vol.10, no.1, 2000, ss.38 - 42.
AMA	ÖZCAN M,LEVINE L,POTTER W Panic provocation studies with placebo. Klinik Psikofarmakoloji Bülteni. 2000; 10(1): 38 - 42.
Vancouver	ÖZCAN M,LEVINE L,POTTER W Panic provocation studies with placebo. Klinik Psikofarmakoloji Bülteni. 2000; 10(1): 38 - 42.
IEEE	ÖZCAN M,LEVINE L,POTTER W "Panic provocation studies with placebo." Klinik Psikofarmakoloji Bülteni, 10, ss.38 - 42, 2000.
ISNAD	ÖZCAN, M. Erkan vd. "Panic provocation studies with placebo". Klinik Psikofarmakoloji Bülteni 10/1 (2000), 38-42.