Yıl: 2000 Cilt: 30 Sayı: 1 Sayfa Aralığı: 43 - 45 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Elevated serum Beta-hCG levels in severe preeclampsia

Öz:
Most current hypotheses regarding the pathophysiologic mechanisms of pregnancy-induced hypertention point to early placental abnormalities. Therefore, we attempted to determine whether serum human chorionic gonadotropin (hCG) levels reflect a different trophoblastic secretory response of preeclampsia. Thirteen pregnant women with severe preeclampsia were matched with twenty-one normotensive pregnant women with singleton pregnancies in the third trimester. Serum $beta$-hCG levels were found to be significantly higher in severe preeclampsia, compared with controls (p<0.05). This indicates that an abnormal secretory function of the placenta exists in patients with severe preeclampsia.
Anahtar Kelime: Placenta Pregnancy Complications Human chorionic gonadotropin Chorionic Gonadotropin Pre-Eclampsia

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Diğer Erişim Türü: Erişime Açık
  • 1. National High Blood Pressure Education Program Working Group on high blood pressure in pregnancy. Am J Obstet Gynecol 163 (suppl): 1691- 712, 1993. 2. Harrington K, Campbells S. Fetal size and growth. Curr Opin Obstet Gynecol 5: 186-94, 1993. 3. Petraglia F, Volpe A, Genazzani AR, Rivier J, Sawchenko PE, Vale W. Neuroendocrinology of the human placenta. Front Neuroendocrinol 11: 6- 37,1990. 4. Redman CWG. Platelets and the beginning of pre-eclampsia. N Engl J Med 323:478-80, 1990. 5. Long PA, Oat JN. Preeclampsia in twin pregnancy: severity and pathogenesis. Aust N Z J Obstet Gynecol 27: 1-5, 1987. 6. Curry SL, Hammond CB, Tyrey L, Creasman WT, Parker RT. Hydatidiform mole: diagnosis, management, and long-term follow-up of 347 patients. Obstet Gynecol 45: 1-8, 1975. 7. Hsu CD, Chan DW, Iriye B, Johnson TRB, Hons SF, Repke JT. Elevated serum human chorionic gonadotropin as evidence of secretory response in severe preeclampsia. Am J Obstet Gyyynecol 170(4): 113 5-8, 1994. 8. Wenstrom KD, Owen J, Boots LR, DuBard MA. Elevated second trimester hCG levels in association with poor pregnancy outcome. Am J 0bstet Gynecol 171 (4): 103 8-41, l994. 9. Onderoglu LS, Kabukçu A. Elevated second trimester human chorionic gonadotropin level associated with adverse pregnancy outcome. Int J Gynecol Obstet 56: 245-249, 1997. 10. Smith GC, Smith OW. Excessive gonadostimulatory hormone and subnormal amounts of oestrin in toxaemia of late pregnancy. Am J Obstet Gynecol 107: 128-45, 1934. 11. Muller F, Savey L, Le Fiblek B, Bussieres L, Ndayizamba G, Colau JC, Giraudet P. Maternal serum human chorionic gonadotrpin level at fifteen weeks is a predictor for preeclampsia. Am J Obstet Gynecol 175:37-39, 1996. 12. Said ME, Campell DM, Azzam ME, MacGillivray I. Beta-human chorionic gonadotropin levels before and after the development of pre-eclampsia. Br J Obstet Gynecol 91: 7872-5, 1984. 13. Adnan MN, Ashour MB, Ellice SL, Louise EWH, John TR. The value of elevated second-trimester b- human chorionic gonadotropin in predicting development of preeclampsia. Am J Obstet Gynecol 176: 438-442, 1997. 14. Anneli MP, Anna LH, Olli JV, Aimo OR, Timo JL. Midtrimester N-terminal Proatrial. Natriuretic Peptide, Free beta hCG, and Alpha-fetoprotein in predicting Preeclampsia. Obstet Gynecol 91: 940-4, 1998. 15. Jones CJP, Fox H. An ultrastructurel and ultrahistochemical study of the human placenta in maternal preeclampsia. Placenta. 1: 61-66, 1980. 16. Hoshina M, Boothby M, Boime I: Cytological localization of chorionic gonadotropin arıd placental lactogen mRNAs during development of the human placenta. J Cell Biol 93: 190-8, 1982. 17. Enders AC. Formation of syncytium from cytotrophoblast in the human placenta. Obstet Grynecol 25: 378- 86, 1965. 18. Kliman HJ, Feimann MA, Strauss JF III: Differentiation of human cytotrophoblast in to syncytotrophoblast in culture. Trophoblast Res 2: 407-21, 1987. 19. Fox H, Khorkongor FN. Immunofluorescent Localization of chorionic gonadotropin in the placenta and in tissue cultures of human trophoblast. J Pathol 101; 277-82, 1970. 21. Crosignani PG. Correlation of human chorionic somatotropin (hCS) with fetal nutrition. In: Sosimovich JB ed. Lactogenic hormones, fetal nutrition and lactation. NY: John Wiley, 1993, pp: 203-220. 22. Fox H. Effect of hypoxia on trophoblast in organ culture: a morphologic and autoradiographic study. Arn J Obstet Gynecol 107: 1058-64, 1970. 23. Frusca T, Morassi L, Pecorelli S, Grigolato P, Gostaldi A. Histological factors of uteroplacental vessels in normal and hypertensive patients in relation to birth weight. Br J Obstet Gynecol 96: 838-9, 1989. 24. Taylor HC, Sçandron EE. Hormone factors in toxaemias of pregnancy, with special reference to quantitative abnormalities of prolan and estrogens in blood and urine. Am J Obstet Gynecol 1939, 3 7: 963-85, 1939. 25. Loraine JA, Matthew GD. Chorionic gonadotropin in toxaemia of pregnancy. J Obstet Br Emp 57: 542- 51, 1954. 26. Teoh ES, Sivasamboo R. Immunological chorionic gonadotropin titres in severe toxaemia of pregnancy. J Obstet Br Commonw 75: 724-7, 1968. 27. Liepmann RE, Williams MA, Chang EY. An association between elevated levels of human chorionic gonadotropin in the midtrimester and adverse pregnancy outcome. Am J Obstet Gynecol 5168: 1852-7, 1993.
APA GÖKDENİZ R, ARIGÜLOĞLU E, BAZOĞLU N, balat o (2000). Elevated serum Beta-hCG levels in severe preeclampsia. , 43 - 45.
Chicago GÖKDENİZ Remzi,ARIGÜLOĞLU Erdal,BAZOĞLU Nursel,balat ozcan Elevated serum Beta-hCG levels in severe preeclampsia. (2000): 43 - 45.
MLA GÖKDENİZ Remzi,ARIGÜLOĞLU Erdal,BAZOĞLU Nursel,balat ozcan Elevated serum Beta-hCG levels in severe preeclampsia. , 2000, ss.43 - 45.
AMA GÖKDENİZ R,ARIGÜLOĞLU E,BAZOĞLU N,balat o Elevated serum Beta-hCG levels in severe preeclampsia. . 2000; 43 - 45.
Vancouver GÖKDENİZ R,ARIGÜLOĞLU E,BAZOĞLU N,balat o Elevated serum Beta-hCG levels in severe preeclampsia. . 2000; 43 - 45.
IEEE GÖKDENİZ R,ARIGÜLOĞLU E,BAZOĞLU N,balat o "Elevated serum Beta-hCG levels in severe preeclampsia." , ss.43 - 45, 2000.
ISNAD GÖKDENİZ, Remzi vd. "Elevated serum Beta-hCG levels in severe preeclampsia". (2000), 43-45.
APA GÖKDENİZ R, ARIGÜLOĞLU E, BAZOĞLU N, balat o (2000). Elevated serum Beta-hCG levels in severe preeclampsia. Turkish Journal of Medical Sciences, 30(1), 43 - 45.
Chicago GÖKDENİZ Remzi,ARIGÜLOĞLU Erdal,BAZOĞLU Nursel,balat ozcan Elevated serum Beta-hCG levels in severe preeclampsia. Turkish Journal of Medical Sciences 30, no.1 (2000): 43 - 45.
MLA GÖKDENİZ Remzi,ARIGÜLOĞLU Erdal,BAZOĞLU Nursel,balat ozcan Elevated serum Beta-hCG levels in severe preeclampsia. Turkish Journal of Medical Sciences, vol.30, no.1, 2000, ss.43 - 45.
AMA GÖKDENİZ R,ARIGÜLOĞLU E,BAZOĞLU N,balat o Elevated serum Beta-hCG levels in severe preeclampsia. Turkish Journal of Medical Sciences. 2000; 30(1): 43 - 45.
Vancouver GÖKDENİZ R,ARIGÜLOĞLU E,BAZOĞLU N,balat o Elevated serum Beta-hCG levels in severe preeclampsia. Turkish Journal of Medical Sciences. 2000; 30(1): 43 - 45.
IEEE GÖKDENİZ R,ARIGÜLOĞLU E,BAZOĞLU N,balat o "Elevated serum Beta-hCG levels in severe preeclampsia." Turkish Journal of Medical Sciences, 30, ss.43 - 45, 2000.
ISNAD GÖKDENİZ, Remzi vd. "Elevated serum Beta-hCG levels in severe preeclampsia". Turkish Journal of Medical Sciences 30/1 (2000), 43-45.