Yıl: 2013 Cilt: 45 Sayı: 1 Sayfa Aralığı: 47 - 49 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Tissue damage and oxidant/antioxidant balance

Öz:
Sağlıklı dokularda oksidan/antioksidan denge antioksidanların üstünlüğüyle sürdürülür. Doku hasarına yol açabilecek çeşitli agresif faktörler oksidan/antioksidan dengenin oksidanların leyhine bozulmasını sağlar. Bu derleme çalışmasında, oksidan/antioksidan dengenin oksidanlar leyhine bozulmasının, antioksidan sistemlerin aşırıharcanmasına bağlı olarak geliştiği rapor edilmiştir. Bu nedenle oksi- datif strese bağlı çeşitli doku hasarının önlenmesinde ve tedavisindeantioksidanların önemli olduğu anlaşılmaktadır.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Doku hasarı ve oksidan/antioksidan denge

Öz:
The oxidant/antioxidant balance in healthy tissues is maintainedwith a predominance of antioxidants. Various factors that can leadto tissue damage disrupt the oxidant/antioxidant balance in favor ofoxidants. In this study, disruptions of the oxidant/antioxidant balancein favor of oxidants were found to be a consequence of the over-con-sumption of antioxidants. For this reason, antioxidants are consid-ered to be of importance in the prevention and treatment of varioustypes of tissue damage that are aggravated by stress.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
  • 1. Clarkson PM, Thompson HS. Antioxidants: What role do they play in physical activity and health? Am J Clin Nutr 2000; 72: 637-46.
  • 2. Yeum KJ, Russell RM, Krinsky NI, Adlini G. Biomarkers of antio- xidan capacity in hydrophilic and lipophilic compartments of human plasma. Arch Biochem Biophys 2004; 430: 97-103.
  • 3. Aguilar A, Alvarez-Vijande R, Capdevila S, Alcoberro J, Alcaraz A. Antioxidant Patterns (Superoxide Dismutase, Glutathione Reductase, and Glutathione Peroxidase) in Kidneys From Non- Heart-Beating- Donors. Transplantation Proceedings 2007; 39: 249-52.
  • 4. Iraz M, Ozerol E, Gulec M, et al. Protective effect of caffeic acid phenethyl ester (CAPE) administration on cisplatin induced oxidative damage to liver in rat. Cell Biochem Funct 2006; 24: 357-61.
  • 5. Uzar E, Acar A, Firat U, et al. Protective effect of caffeic acid phenethyl ester in rat cerebral ıschemia/reperfusion damage. Turk Norol Derg 2011; 17: 131-6.
  • 6. Bayir H, Kagan VE, Borisenko GG, et al. Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS. J Cereb Blood Flow Metab 2005; 25: 673-84.
  • 7. Chong ZZ, Li F, Maiese K. Oxidative stress in the brain: Novel cellular targets that governsurvival during neurodegenerative disease. Prog Neurobiol 2005; 75: 207-46.
  • 8. Shao CX, Roberts KN, Markesbery WR, Scheff SW, Lovell MA. Oxidative stress in head trauma in aging. Free Radic Biol Med 2006; 41: 77-85.
  • 9. Eşmekaya MA, Sırav B, Ozer C, Seyhan N. Effects of radiofrequ- ency radiation on brain tissue oxidant and antioxidant levels in rats. Gazi Med J 2011; 22: 100-4.
  • 10. Lefer DJ, Granger DN. Oxidative stress and cardiac disease. Am J Med 2000; 109: 315-23.
  • 11. Dhalla NS, Elmoselhi AB, Hata T, Makino N. Status of myocardial antioxidants in ischemia-reperfusion injury. Cardiovasc Res 2000; 47: 446-56.
  • 12. Kelly RF. Current strategies in lung preservation. J Lab Clin Med 2000; 136, 427-40.
  • 13. Zhao G, Al-Mehdi AB, Fisher AB. Anoxia-reoxygenation versus ischemia in isolated rat lungs. Am J Physiol 1997; 273: 1112-7.
  • 14. Al-Mehdi AB, Shuman H, Fisher AB. Intracellular generation of reactive oxygen species during nonhypoxic lung ischemia. Am J Physiol 1997; 272: 294-300.
  • 15. Fisher AB, Dodia C, Tan ZT, Ayene I, Eckenhoff RG. Oxygen- dependent lipid peroxidation during lung ischemia. J Clin Invest 1991; 88: 674-9.
  • 16. Eckenhoff RG, Dodia C, Tan Z, Fisher AB. Oxygen-dependent reperfusion injury in the isolated rat lung. J Appl Physiol 1992; 72: 1454-60.
  • 17. Harton JW, Walker PB. Oxygen radicals, lipid peroxidation and permeability changes after intestinal ischemia and reperfusion. J Appl 1993; 74: 1515-20.
  • 18. Bilbao G, Contrenas JL. Reduction of ischemia reperfusion injury of the liver by vivo adenovirus mediated gene transfer of the antiapoptotic Bcl-2 gene. Ann Surg 1999; 230: 185-93.
  • 19. Weight SC, Bell PR, Nicholson ML. Renal ischemia reperfusion injury. Br J Surg 1996; 83: 162-70.
  • 20. Collard CD, Gehran S. Phatophysiology, clinical manifestations and prevention of ischemia reperfusion injury. Anest 2001; 94: 1122-38.
  • 21. Carden DL, Granger DN. Phatophysiology of ischemia reperfusion injury. J Pathol 2000; 190: 255-66.
  • 22. Chamoun F, Burne M, O’Donnell M, Rabb H. Phatophysiologic role of selectins and their ligands in ischemia reperfusion injury. Front Bioscl 2000; 5: 103-9.
  • 23. Tok A, Sener E, Albayrak A, et al. Effect of mirtazapine on oxidati- ve stress created in rat kidneys by ischemia-reperfusion. Ren Fai 2012; 34: 103-10.
  • 24. Yigiter M, Yildiz A, Polat B, et al. The protective effects of mety- rosine, lacidipine, clonidine, and moxonidine on kidney damage induced by unilateral ureteral obstruction in rats. Surg Today 2012; 42: 1051-60.
  • 25. Ingec M, Isaoglu U, Yilmaz M, et al. Prevention of ischemia- reperfusion injury in rat ovarian tissue with the on-off method. J Physiol Pharmacol 2011; 62: 575-82.
  • 26. Kurt A, Isaoglu U, Yilmaz M, et al. Biochemical and histological investigation of famotidine effect on postischemic reperfusion injury in the rat ovary. J Pediatr Surg 2011; 46: 1817-23.
  • 27. Isaoglu U, Yilmaz M, Calik M, et al. Biochemical and histopatholo- gical investigation of the protective effect of disulfiram in ische- mia-induced ovary damage. Gynecol Endocrinol 2012; 28: 143-7.
  • 28. Salman S, Kumbasar S, Yilmaz M, et al. Investigation of the effects of the chronic administration of some antihypertensive drugs on enzymatic and non-enzymatic oxidant/antioxidant parameters in rat ovarian tissue. Gynecol Endocrinol 2011; 27: 895-9.
  • 29. Derin N, Izgut-Uysal VN, Agac A, Aliciguzel Y, Demir N. L-carnitine protects gastric mucosa by decreasing ischemia-reperfusion indu- ced lipid peroxidation. J Physiol Pharmacol 2004; 55: 595-606.
  • 30. Akgun S, Tekeli A, Kurtkaya O, et al. Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia- reperfusion injury. Eur J Cardiothorac Surg 2004; 25: 105-10.
  • 31. Kocer I, Kulacoglu D, Altuntas I, Gundogdu C, Gullulu G. Protection of the retina from ischemia-reperfusion injury by L-carnitine in guinea pigs. Eur J Ophthalmol 2003; 13: 80-5.
  • 32. Onal A, Astarcıoglu H, Ormen M, Atila K, Sarioglu S. The benefi- cial effect of L-carnitine in rat renal ischemia-reperfusion injury. Ulus Travma Derg 2004; 10: 160-7.
  • 33. Atila K, Coker A, Sagol O, et al. Protective effects of carnitine in an experimental ischemia-reperfusion injury. Clin Nutr 2002; 21: 309-13.
  • 34. Calvani M, Arrigoni-Martelli E. Attenuation by acetyl-L-carnitine of neurological damage and biochemical derangement following brain ischemia and reperfusion. Int J Tissue React 1999; 21: 1-6.
  • 35. Kourounakis PN, Tsiakitzis K, Kourounakis AP, Galanakis D. Reduction of gastrointestinal toxicity of NSAIDs via molecular modifications leading to antioxidant anti-inflammatory drugs. Toxicology 2000; 144: 205-10.
  • 36. Wallace JL. Mechanisms of nonsteroidal anti-inflammatory drug (NSAID) induced gastrointestinal damage-potential for development of gastrointestinal tract safe NSAIDs. Can J Physiol Pharmacol 1994; 72: 1493-8.
  • 37. Niki E, Yamamoto Y, Komuro E, Sato K. Membrane damage due to lipid oxidation. Am J Clin Nutr 1991; 53: 201-5.
  • 38. Mitch WE, Goldberg AL. Mechanisms of muscle wasting. The role of the ubiquitinproteasome pathway. N Engl J Med 1996; 335: 1897-905.
  • 39. Cuzzocrea S, Reiter RJ. Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury. Eur J Pharmacol 2001; 426: 1-10.
  • 40. Sorg O. Oxidative stres: a theoretical model or biological reality? C R Biologies 2004; 327: 649-62.
APA KISAOĞLU A, Börekçi B, YAPCA O, BİLEN H, Suleyman H (2013). Tissue damage and oxidant/antioxidant balance. , 47 - 49.
Chicago KISAOĞLU Abdullah,Börekçi Bünyamin,YAPCA O. Erkan,BİLEN Habib,Suleyman Halis Tissue damage and oxidant/antioxidant balance. (2013): 47 - 49.
MLA KISAOĞLU Abdullah,Börekçi Bünyamin,YAPCA O. Erkan,BİLEN Habib,Suleyman Halis Tissue damage and oxidant/antioxidant balance. , 2013, ss.47 - 49.
AMA KISAOĞLU A,Börekçi B,YAPCA O,BİLEN H,Suleyman H Tissue damage and oxidant/antioxidant balance. . 2013; 47 - 49.
Vancouver KISAOĞLU A,Börekçi B,YAPCA O,BİLEN H,Suleyman H Tissue damage and oxidant/antioxidant balance. . 2013; 47 - 49.
IEEE KISAOĞLU A,Börekçi B,YAPCA O,BİLEN H,Suleyman H "Tissue damage and oxidant/antioxidant balance." , ss.47 - 49, 2013.
ISNAD KISAOĞLU, Abdullah vd. "Tissue damage and oxidant/antioxidant balance". (2013), 47-49.
APA KISAOĞLU A, Börekçi B, YAPCA O, BİLEN H, Suleyman H (2013). Tissue damage and oxidant/antioxidant balance. Eurasian Journal of Medicine, 45(1), 47 - 49.
Chicago KISAOĞLU Abdullah,Börekçi Bünyamin,YAPCA O. Erkan,BİLEN Habib,Suleyman Halis Tissue damage and oxidant/antioxidant balance. Eurasian Journal of Medicine 45, no.1 (2013): 47 - 49.
MLA KISAOĞLU Abdullah,Börekçi Bünyamin,YAPCA O. Erkan,BİLEN Habib,Suleyman Halis Tissue damage and oxidant/antioxidant balance. Eurasian Journal of Medicine, vol.45, no.1, 2013, ss.47 - 49.
AMA KISAOĞLU A,Börekçi B,YAPCA O,BİLEN H,Suleyman H Tissue damage and oxidant/antioxidant balance. Eurasian Journal of Medicine. 2013; 45(1): 47 - 49.
Vancouver KISAOĞLU A,Börekçi B,YAPCA O,BİLEN H,Suleyman H Tissue damage and oxidant/antioxidant balance. Eurasian Journal of Medicine. 2013; 45(1): 47 - 49.
IEEE KISAOĞLU A,Börekçi B,YAPCA O,BİLEN H,Suleyman H "Tissue damage and oxidant/antioxidant balance." Eurasian Journal of Medicine, 45, ss.47 - 49, 2013.
ISNAD KISAOĞLU, Abdullah vd. "Tissue damage and oxidant/antioxidant balance". Eurasian Journal of Medicine 45/1 (2013), 47-49.