Aim: Deterioration of functional status is a critical point being the most important indication for valve replacement surgery. In this study on patients with mild or moderate aortic stenosis (AS), association of angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism with functional capacity markers and left ventricular phenotype in echocardiography was evaluated. Material and Method: ACE gene polymorphism and functional capacity which was measured with New York Heart Association clas- sification, 6 minute walk test and plasma NT-proBNP levels were assessed in twenty two asymptomatic patient with echocardio- graphically documented mild-moderate AS. Results: Age, hypertension, degenerative stenosis and aortic valvular calsification were related with worse functional capacity (p<0,05). ACE gene polymorphism was not associated with functional capacity. DD genotype was associated with eccentric modelling in normotensive patients (p:0.03). Among either hypertensive patients or patients over 40 years subjects with DD genotype had more significant left ventricular hypertrophy (190.1±22.2 g/m2 vs 132,1±12,8 g/m2; p:0.004 and 181,9±29,6 g/m2 vs 142,8±36,3 g/m2; p:0,02 respectively). Conclusion: Closer follow up of elderly, hypertensive, degenerative and calcified mild-moderate AD patients for deterioration of func- tional capacity may be suitable. Mild-moderate AD patients older than 40 years or with hypertension have more significant left ventricular hypertrophy if they have DD genotype.