In this report, a case of toxic shock syndrome (TSS) due to group A beta-hemolytic streptococci (GABHS) in a 39 years old female patient, with soft tissue infection after the nail injury of right forearm, has been presented. Streptococcal TSS is similar to staphylococcal TSS with the combination of typical shock symptoms and signs, multiorgan insufficiency and rapidly progressing necrotizing fasciitis. The positive findings for Streptococcal TSS in our case were shock, isolation of GABHS from the wound, renal insufficiency, trombocytopenia, hepatic involvement, soft tissue necrosis, and fasciitis. According to the criteria of "The Working Group on Severe Streptococcal Infections", the scores of this infection were classified as type IB and II Streptococcal TSS. The patient was treated by intravenous ampicillin/sulbactam 4x1.5 g/day, dopamin 5 ug/kg/day, prednisolon 20 mg/day and oral levotiroxin 0.1 mg/day. The antibiotic therapy continued for 14 days and the patient was discharged with complete healing. In conclusion, it should be kept in mind that, streptococcal soft tissue infections might be manifested as toxic shock syndrome.