Objectives: Insufficient removal of caries- affected enamel and dentin represents a seriousproblem in restorative dentistry, as any bacteriaremaining in the cavity after preparation may causesecondary caries. In order to provide an asepticenvironment before pulp capping and lining, the useof an antibacterial material as a cavity disinfectanthas been recommended. The aim of this study wasto evaluate the role of commercially available gelformulations on the micro-tensile bond strength(MTBS) of a total etch system. Materials and Methods: Commerciallyavailable gel formulations with the contents ofchlorhexidine (Corsodyl gel- %1CHX-COG),(Cervitec gel-%0.2 CHX+%0.2 sodium fluoride- CEG), aloe vera (Forever Bright-FOB) andhyaluronic acid (Gengigel-GEG) applicable ascavity disinfectants were used. No disinfectant wasapplied in the control group (CON). Ten humanthird molar free of caries were used in the study.Gels were applied for 1 minute just before bondingfollowing total etch application in the gel groups,removed with sterile pellets and air-dried. Thencomposite restorations were applied. Tencomposite-dentin rods (surface area of 1.0±0.1mm2) were generated in each group from specimensstored in distilled water in 370C for 24 hours. Thesespecimens then were subjected to MTBS testapplying at a crosshead speed of 1 mm/min. Bondstrength values between composite-dentin wererecorded as megapascal and failure types wereevaluated. Statistical differences were evaluatedwith one-way ANOVA and Tukey s test at thesignifince level of p<0.05. Results: All the gels applied created lowerMTBS levels compared with CON group (p<0.05).No difference was detected among the gels;CEG>COG>GEG>FOB (p>0.05). While mixedfailure type was dominant in the CON group, onlyadhesive failure type was observed in all the othergroups. Conclusions: Besides the antibacterialproperties of these gel formulations, alterationsoccured in micromechanical adhesion and clinicalperformances should not be overlooked.