NUR CANPOLAT
(İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı, İstanbul, Türkiye)
Yıl: 2015Cilt: 50Sayı: 2ISSN: 1306-0015 / 1308-6278Sayfa Aralığı: 73 - 82Türkçe

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Hemolitik üremik sendrom
Hemolitik üremik sendrom (HÜS) mikroanjiopatik hemolitik anemi, trombositopeni ve akut böbrek hasarı üçlüsü ile tanımlanan bir klinik tablodur. Hemolitik üremik sendrom etiyolojileri, seyirleri ve tedavi yaklaşımları farklı olan bir grup hastalıktan oluşur. Son yıllarda HÜS’e yol açan hastalıkların daha iyi anlaşılması, özellikle kompleman ilişkili HÜS olgularında genetik mutasyonların gösterilmesi hastalığa ait tanımlar, sı- nıflamalar ve tedavi yaklaşımlarında güncellemelere neden olmuştur. Bu yazıda hastalığın güncel sınıflaması, çocukluk çağındaki HÜS’ün en sık nedeni olan STEC-HÜS ve yeni tanı ve tedavi yaklaşımları ile kompleman ilişkili HÜS anlatılacaktır.
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