Yıl: 2015 Cilt: 5 Sayı: 02 Sayfa Aralığı: 93 - 98 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Middle East Respiratory Syndrome: MERS

Öz:
Orta Doğu Solunum Sendromu coronovirüsü (MERS-CoV) yeni ortaya çıkan bir solunum virüsüdür. Bu virus ilk olarak 2012 yılında Suudi Arabistan'da tanımlanmıştır. Orta Doğu solunum sendromu koronavirüs enfeksiyonu akut hafif bir hastalık ile fulminan hastalık arasında değişen bir klinik spektrum ile karakterizedir. Hastaların çoğunluğunda ateş, ateş ile titreme, öksürük, nefes darlığı ve kuru öksürük bildirilmiştir. İnsandan insana bulaşan vakalar belgelenmiştir. MERSCoV enfeksiyonu için günümüzde özel bir tedavi ve aşılama yoktur. Sürveyans ve infeksiyon kontrol önlemleri halk sağlığı için hayati öneme sahiptir
Anahtar Kelime:

Konular: Mikrobiyoloji Enfeksiyon Hastalıkları

Orta Doğu Solunum Sendromu: MERS

Öz:
Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly emerging respiratory virus. It was first identified in Saudi Arabia in 2012. MERS-CoV infection is characterized by a spectrum of illness ranging from mild to acute and fulminant disease. The majority of patients present with fever, fever with chills/rigors, cough, shortness of breath, and dry cough. Cases of human-to-human transmission have been documented. There is currently no specific treatment and vaccination for MERS-CoV infection. Surveillance and infection-control measures are of vital importance to an efficient public health response. J Microbiol Infect Dis 2015;5(2): 93-98
Anahtar Kelime:

Konular: Mikrobiyoloji Enfeksiyon Hastalıkları
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
  • De Groot RJ, Baker SC, Baric RS, et al. Middle East respiratory syn- drome coronavirus (MERS-CoV): Announcement of the coronavirus study group. J Virol 2013;87:7790-7792.
  • MacIntyre CR. The discrepant epidemiology of Middle East respi- ratory syndrome coronavirus (MERS-CoV). Environ Syst Decis 2014;34:383-390.
  • Bermingham A, Chand MA, Brown CS, et al. Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the Unit- ed Kingdom from the Middle East, September 2012. Euro Surveill. 2012;17:20290.
  • Announcement of the Coronavirus Study Group. Middle East Respira- tory Syn 1 drome Coronavirus (MERS-CoV). J. Virol 2013;87:7790- 7792.
  • Raj VS, Osterhaus AD, Fouchier RM, et al. MERS: emergence of a novel human coronavirus. Curr Opin Virol 2014;5:58-62.
  • Zaki AM, van Boheemen S, Bestebroer TM, et al. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 2012;367:1814-1820.
  • Al-Tawfiq JA, Assiri A, Memish ZA. Middle East respiratory syndrome novel corona (MERS-CoV) infection Epidemiology and outcome up- date. Saudi Med J 2013;34:991-994.
  • World Health Organization. Global alert and response (GAR): pandemic and epidemic diseases (http://www.who.int/csr/disease/en/)
  • Guery B, Poissy J, el Mansouf L, et al. Clinical features and viral di- agnosis of two cases of infection with Middle East Respiratory Syn- drome coronavirus: A report of nosocomial transmission. Lancet 2013;381:2265-2272.
  • Breban R, Riou J, Fontanet A. Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk. Lancet 2013;382:694-699.
  • Memish ZA, Zumla AI, Al-Hakeem RF, et al. Family cluster of Middle East respiratory syndrome coronavirus infections. N Engl J Med 2013;368:2487-2494.
  • Health Protection Agency (HPA) UK Novel Coronavirus Investigation Team. Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013. Euro Surveill 2013;18:20427.
  • Puzelli S, Azzi A, Santini MG, et al. Investigation of an imported case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infec- tion in Florence, Italy, May to June 2013. Euro Surveill 2013;18:20564.
  • Abroug F, Slim A, Ouanes-Besbes L. Family cluster of Middle East respiratory syndrome coronavirus infections, Tunisia, 2013 Emerg Infect Dis 2014;20:1527-1530.
  • Assiri A, McGeer A, Perl TM, et al. Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med 2013;369:407-416.
  • Cotten M, Watson SJ, Kellam P, et al. Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study. Lancet 2013;382:1993-2002.
  • Omrani AS, Matin MA, Haddad Q, et al. A family cluster of Middle East respiratory syndrome coronavirus infections related to a likely unrec- ognized asymptomatic or mild case. Int J Infect Dis 2013;17:e668- e672.
  • De Sousa R, Reusken C, Koopmans M. MERS coronavirus: Data gaps for laboratory preparedness. J Clin Virol 2014;59:4-11.
  • Bauch CT, Oraby T. Assessing the pandemic potential of MERS-CoV. Lancet 2013;382:662-664.
  • Drosten C, Seilmaier M, Corman VM, et al. Transmission of MERS- Coronavirus in household contacts. N Engl J Med 2014;371:828-835.
  • Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, et al. Epidemiological, demo- graphic, and clinical characteristics of 47 cases of Middle East respi- ratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis 2013;13:752-761.
  • Memish ZA, Almasri M, Turkestani A, et al. Etiology of severe commu- nity-acquired pneumonia during the 2013 Hajj-part of the MERS-CoV surveillance program. Int J Infec Dis 2014;25:186-190.
  • Eckerle I, Müller MA, Kallies S, et al. In-vitro renal epithelial cell infec- tion reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coro- navirus infection. Virol J 2013;10:359.
  • Memish ZA, Al-Tawfig JA, Makhdoom HQ, et al. Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective de- scriptive study. Clin Microbiol Infect 2014;20(5):469-474.
  • http://who.int/csr/disease/coronavirus_infections/MERS_home
  • Memish MA, Cotton M, Meyer B, et al. Human Infection with MERS Coronavirus after Exposure to Infected Camels, Saudi Arabia, 2013. Emerg Infect Dis 2014;20:1012-1015.
  • Reusken CB, Lina PH, Pielaat A, et al. Middle East respiratory syn- drome coronavirus neutralising serum antibodies in dromedary cam- els: a comparative serological study. Lancet Infect Dis 2013;13:859- 866.
  • Azhar EI, El-Kafrawy S A, Farraj S A, et al. Evidence for Camel- to-Human Transmission of MERS Coronavirus. N Engl J Med 2014;370:2499-2505.
  • Cotten M, Watson SJ, Kellam P, et al. Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study. Lancet 2013;382:1993-2002.
  • Corman V, Eckerle I, Bleicker T, et al. Detection of a novel human coro- navirus by real-time reverse-transcription polymerase chain reaction. Euro Surveill 2012;17:20285.
  • Hijawi B, Abdallat M, Sayaydeh A, et al. Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. East Mediterr Health J. 2013;19:S12-18.
  • Momattin H, Mohammed K, Zumla A, et al. Therapeutic Options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) - pos- sible lessons from a systematic review of SARS-CoV therapy. Int J Infect Dis 2013;17:e792-e798.
  • Balkhair A, Al Maamari K, Alawi FB. The struggle against MERS-CoV (The Novel Coronavirus). Oman Med J 2013;28:226-227.
  • Wilde AH, Raj S, Oudshoorn D, et al. MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cy- closporin A or interferon-a treatment. J Gen Virol 2013;94:1749-1760.
  • Omrani AS, Saad MM, Baig K, et al. Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study. Lancet Infect Dis 2014;14:1090-1095.
  • Pavli A, Tsiodras S, Maltezou HC. Middle East respiratory syndrome coronavirus (MERS-CoV): Prevention in travelers. Travel Med and Infect Dis 2014;12:602-608.
APA PARLAK E (2015). Middle East Respiratory Syndrome: MERS. , 93 - 98.
Chicago PARLAK Emine Middle East Respiratory Syndrome: MERS. (2015): 93 - 98.
MLA PARLAK Emine Middle East Respiratory Syndrome: MERS. , 2015, ss.93 - 98.
AMA PARLAK E Middle East Respiratory Syndrome: MERS. . 2015; 93 - 98.
Vancouver PARLAK E Middle East Respiratory Syndrome: MERS. . 2015; 93 - 98.
IEEE PARLAK E "Middle East Respiratory Syndrome: MERS." , ss.93 - 98, 2015.
ISNAD PARLAK, Emine. "Middle East Respiratory Syndrome: MERS". (2015), 93-98.
APA PARLAK E (2015). Middle East Respiratory Syndrome: MERS. Journal of Microbiology and Infectious Diseases, 5(02), 93 - 98.
Chicago PARLAK Emine Middle East Respiratory Syndrome: MERS. Journal of Microbiology and Infectious Diseases 5, no.02 (2015): 93 - 98.
MLA PARLAK Emine Middle East Respiratory Syndrome: MERS. Journal of Microbiology and Infectious Diseases, vol.5, no.02, 2015, ss.93 - 98.
AMA PARLAK E Middle East Respiratory Syndrome: MERS. Journal of Microbiology and Infectious Diseases. 2015; 5(02): 93 - 98.
Vancouver PARLAK E Middle East Respiratory Syndrome: MERS. Journal of Microbiology and Infectious Diseases. 2015; 5(02): 93 - 98.
IEEE PARLAK E "Middle East Respiratory Syndrome: MERS." Journal of Microbiology and Infectious Diseases, 5, ss.93 - 98, 2015.
ISNAD PARLAK, Emine. "Middle East Respiratory Syndrome: MERS". Journal of Microbiology and Infectious Diseases 5/02 (2015), 93-98.