Osteogenesis imperfecta is a rare , inherited genetic disor-der of connective tissue which is characterized by abnormal Type I collagen production. This causes decrease in bone mass of human body, bones become fragile and brittle, re-sulting in unreasonable multiple fractures. Other manifes-tations include hyperextensibility of the joints, blue sclera, hearing loss, short stature and dentinogenesis imperfecta. During the anesthetic management of these patients, intu-bation difficulties, cervical spine fractures, and malignant hyperthermia triggered by used anesthetic agents may de-velop. Anatomic deformities and platelet dysfunction influ-ence the choice of anesthetic technique. We aimed to pre-sent a series of 7 general anaesthetics in one child patient suffering from this disease along with the literature.