Yıl: 2013 Cilt: 20 Sayı: 1 Sayfa Aralığı: 74 - 76 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report

Öz:
Double-Hit lenfoma acil tedavi edilmez ise aylar içinde ölümcül olabilen kötü seyirli B hücreli lenfomadır. Biz burada kötü seyirli giden fatal seyreden Double-Hit Lenfomalı erişkin bir olguyu sunduk. 18 yaşındaki erkek hasta Kulak Burun Boğaz polikliniğine çene altındaki şişlik nedeni ile başvurdu ve eksizyonel biopsi yapıldı. Hastanın biyopsisi CD20(+) Burkitt-like lenfoma olarak rapor edildi. Ann-Arbor evreleme sistemine göre evre IIIB kabul edilen hasta tedavi protokolündeki kemoterapotiklere ve yüksek doz kemoterapi eşliğinde otolog kemik iliği nakline cevap vermedi. Hastamız tanı konulmasından yaklaşık 12 ay sonra kaybedildi. Double-Hit lenfoma agresif gidişli olabilir ve fatal seyirli seyredebilir. Bu yüzden tanıdan sonra zaman kaybetmeden tedavi başlanmalıdır.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Agresif Seyreden Double-Hit Lenfoma: Bir olgu sunumu

Öz:
Double-Hit lymphoma is an aggressive B-cell malignancy with a high proliferative rate that may be fatal within months if not treated promptly. We presented a very aggressive and fatal case of a Double-Hit Lymphoma. 18 years old male patient referred Ear-NoseThroat outpatient clinic due to swelling under the chin and an excisional biopsy was performed. High grade Burkitt like lymphoma CD20 (+) was reported. Approximately 12 months after diagnosis patient who was accepted as a stage IIIB according to Ann-Arbor staging system died of disease progression despite the various treatment protocols of high dose chemotherapy followed by autologous bone marrow transplantation. Double-Hit lymphoma is aggressive and can be fatal. Therefore, treatment should be initiated without delay after diagnosis.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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APA KAYA E, ERKURT M, BERBER İ, KÖROĞLU M, KUKU İ (2013). Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. , 74 - 76.
Chicago KAYA Emin,ERKURT Mehmet Ali,BERBER İlhami,KÖROĞLU Mustafa,KUKU İrfan Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. (2013): 74 - 76.
MLA KAYA Emin,ERKURT Mehmet Ali,BERBER İlhami,KÖROĞLU Mustafa,KUKU İrfan Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. , 2013, ss.74 - 76.
AMA KAYA E,ERKURT M,BERBER İ,KÖROĞLU M,KUKU İ Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. . 2013; 74 - 76.
Vancouver KAYA E,ERKURT M,BERBER İ,KÖROĞLU M,KUKU İ Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. . 2013; 74 - 76.
IEEE KAYA E,ERKURT M,BERBER İ,KÖROĞLU M,KUKU İ "Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report." , ss.74 - 76, 2013.
ISNAD KAYA, Emin vd. "Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report". (2013), 74-76.
APA KAYA E, ERKURT M, BERBER İ, KÖROĞLU M, KUKU İ (2013). Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 20(1), 74 - 76.
Chicago KAYA Emin,ERKURT Mehmet Ali,BERBER İlhami,KÖROĞLU Mustafa,KUKU İrfan Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi 20, no.1 (2013): 74 - 76.
MLA KAYA Emin,ERKURT Mehmet Ali,BERBER İlhami,KÖROĞLU Mustafa,KUKU İrfan Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, vol.20, no.1, 2013, ss.74 - 76.
AMA KAYA E,ERKURT M,BERBER İ,KÖROĞLU M,KUKU İ Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi. 2013; 20(1): 74 - 76.
Vancouver KAYA E,ERKURT M,BERBER İ,KÖROĞLU M,KUKU İ Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi. 2013; 20(1): 74 - 76.
IEEE KAYA E,ERKURT M,BERBER İ,KÖROĞLU M,KUKU İ "Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report." İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 20, ss.74 - 76, 2013.
ISNAD KAYA, Emin vd. "Double-Hit Lymphoma Presenting with Aggressive Progression: A Case Report". İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi 20/1 (2013), 74-76.