Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD

TANELİ, FATMA; GÜVENÇ DEMİRAĞCI, YEŞİM; ÇETİNKAYA, Cemile; Ulman, Cevval; ŞAKAR COŞKUN, AYŞIN; DİNÇ HORASAN, Gönül; ULUTAŞ, Gürol Şahin; ÖZGEN ALPAYDIN, Aylin

Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD

Gürol Şahin ULUTAŞ, (Uşak Devlet Hastanesi, Klinik Biyokimya, Uşak, Türkiye)

Aylin ÖZGEN ALPAYDIN, (Dokuz Eylül Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı,İzmir, Türkiye)

Fatma TANELİ, (Celal Bayar Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Manisa, Türkiye)

Cemile ÇETİNKAYA, (Celal Bayar Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Manisa, Türkiye)

Cevval ULMAN, (Celal Bayar Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Manisa, Türkiye)

YEŞİM GÜVENÇ DEMİRAĞCI, (Celal Bayar Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Manisa, Türkiye)

Gönül Dinç HORASAN, (Celal Bayar Üniversitesi, Tıp Fakültesi, Halk Sağlığı Anabilim Dalı, Manisa, Türkiye)

Ayşın Şakar COŞKUN (Celal Bayar Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Manisa, Türkiye)

Türk Toraks Dergisi

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Yıl: 2014 Cilt: 15 Sayı: 3 Sayfa Aralığı: 106 - 111 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD

Öz:

as well as the relationship of these cells with pulmonary functions in chronic obstructive pulmonary disease (COPD) patients.MATerIAL ANd MeTHods: Forty COPD patients and 40 healthy volunteers were included. Participants were analysed in four groups according to their smoking status. Peripheral blood CD4+ and CD8+ T cells and monocyte TLR-2 expression were measured by flow cytometry in the whole study population.resULTs: No significant difference was observed in TLR-2 expression, number of CD4+ and CD8+ T cells, and CD4+/CD8+ T cell ratio between the study groups. CD4+/CD8+ T cell ratio and FEV1/FVC were found to have a mild positive correlation (r=0.295, p=0.022). A mild negative correlation was observed between smoking intensity and CD4+/CD8+ T cell ratio (r=-0.274, p=0.034).CoNCLUsIoN: We demonstrated a mild correlation between pulmonary functions and peripheral blood CD4+/CD8+ T cell ratio. However, we did not find a significant difference in TLR-2 expression of CD14+ monocytes in patients with airway obstruction.

Anahtar Kelime:

Konular: Solunum Sistemi Kulak, Burun, Boğaz

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ULUTAŞ G, ÖZGEN ALPAYDIN A, TANELİ F, ÇETİNKAYA C, Ulman C, GÜVENÇ DEMİRAĞCI Y, DİNÇ HORASAN G, ŞAKAR COŞKUN A (2014). Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. , 106 - 111.
Chicago	ULUTAŞ Gürol Şahin,ÖZGEN ALPAYDIN Aylin,TANELİ FATMA,ÇETİNKAYA Cemile,Ulman Cevval,GÜVENÇ DEMİRAĞCI YEŞİM,DİNÇ HORASAN Gönül,ŞAKAR COŞKUN AYŞIN Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. (2014): 106 - 111.
MLA	ULUTAŞ Gürol Şahin,ÖZGEN ALPAYDIN Aylin,TANELİ FATMA,ÇETİNKAYA Cemile,Ulman Cevval,GÜVENÇ DEMİRAĞCI YEŞİM,DİNÇ HORASAN Gönül,ŞAKAR COŞKUN AYŞIN Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. , 2014, ss.106 - 111.
AMA	ULUTAŞ G,ÖZGEN ALPAYDIN A,TANELİ F,ÇETİNKAYA C,Ulman C,GÜVENÇ DEMİRAĞCI Y,DİNÇ HORASAN G,ŞAKAR COŞKUN A Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. . 2014; 106 - 111.
Vancouver	ULUTAŞ G,ÖZGEN ALPAYDIN A,TANELİ F,ÇETİNKAYA C,Ulman C,GÜVENÇ DEMİRAĞCI Y,DİNÇ HORASAN G,ŞAKAR COŞKUN A Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. . 2014; 106 - 111.
IEEE	ULUTAŞ G,ÖZGEN ALPAYDIN A,TANELİ F,ÇETİNKAYA C,Ulman C,GÜVENÇ DEMİRAĞCI Y,DİNÇ HORASAN G,ŞAKAR COŞKUN A "Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD." , ss.106 - 111, 2014.
ISNAD	ULUTAŞ, Gürol Şahin vd. "Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD". (2014), 106-111.

APA	ULUTAŞ G, ÖZGEN ALPAYDIN A, TANELİ F, ÇETİNKAYA C, Ulman C, GÜVENÇ DEMİRAĞCI Y, DİNÇ HORASAN G, ŞAKAR COŞKUN A (2014). Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. Türk Toraks Dergisi, 15(3), 106 - 111.
Chicago	ULUTAŞ Gürol Şahin,ÖZGEN ALPAYDIN Aylin,TANELİ FATMA,ÇETİNKAYA Cemile,Ulman Cevval,GÜVENÇ DEMİRAĞCI YEŞİM,DİNÇ HORASAN Gönül,ŞAKAR COŞKUN AYŞIN Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. Türk Toraks Dergisi 15, no.3 (2014): 106 - 111.
MLA	ULUTAŞ Gürol Şahin,ÖZGEN ALPAYDIN Aylin,TANELİ FATMA,ÇETİNKAYA Cemile,Ulman Cevval,GÜVENÇ DEMİRAĞCI YEŞİM,DİNÇ HORASAN Gönül,ŞAKAR COŞKUN AYŞIN Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. Türk Toraks Dergisi, vol.15, no.3, 2014, ss.106 - 111.
AMA	ULUTAŞ G,ÖZGEN ALPAYDIN A,TANELİ F,ÇETİNKAYA C,Ulman C,GÜVENÇ DEMİRAĞCI Y,DİNÇ HORASAN G,ŞAKAR COŞKUN A Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. Türk Toraks Dergisi. 2014; 15(3): 106 - 111.
Vancouver	ULUTAŞ G,ÖZGEN ALPAYDIN A,TANELİ F,ÇETİNKAYA C,Ulman C,GÜVENÇ DEMİRAĞCI Y,DİNÇ HORASAN G,ŞAKAR COŞKUN A Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. Türk Toraks Dergisi. 2014; 15(3): 106 - 111.
IEEE	ULUTAŞ G,ÖZGEN ALPAYDIN A,TANELİ F,ÇETİNKAYA C,Ulman C,GÜVENÇ DEMİRAĞCI Y,DİNÇ HORASAN G,ŞAKAR COŞKUN A "Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD." Türk Toraks Dergisi, 15, ss.106 - 111, 2014.
ISNAD	ULUTAŞ, Gürol Şahin vd. "Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD". Türk Toraks Dergisi 15/3 (2014), 106-111.