Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition

ÖZCAN, Ömer; UYUMAZ, Ali Serdal; AKTAŞ, Zeki; Tonyali, Senol; ATEŞ, Ferhat; MALKOÇ, Ercan; KARA, Önder; Şenkul, Temuçin

Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition

Önder KARA, (Department of Urology, Amasya University Faculty of Medicine, Amasya, Turkey)

Ercan MALKOÇ, (Department of Urology, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul, Turkey)

Şenol TONYALI, (Department of Urology, Türkiye Yüksek İhtisas Training and Research Hospital, Ankara, Turkey)

Ferhat ATEŞ, (Department of Urology, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul, Turkey)

Ali Serdal UYUMAZ, (Department of Biochemistry, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul, Turkey)

Ömer ÖZCAN, (Department of Biochemistry, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul, Turkey)

Zeki AKTAŞ, (Department of Urology, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul, Turkey)

Temuçin ŞENKUL (Department of Urology, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul, Turkey)

Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi

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Yıl: 2016 Cilt: 27 Sayı: 3 Sayfa Aralığı: 195 - 199 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition

Öz:

Amaç: Bu çalışmada, üriner sistem taşlarının analizinde kullanılan kimyasal yöntemin güncel taş hastalığı kılavuzlarında yer alan taş tip ve bileşenlerini kategorize etmedeki etkinliği araştırıldı. Gereç ve Yöntem: Mart 2014 ile Eylül 2015 tarihleri arasında toplam 198 üriner sistem taşının kimyasal incelemesi yapıldı. Kimyasal yöntemde taş içeriğinde bulunan kalsiyum, oksalat, ürik asit, magnezyum, fosfat, sistin, amonyum ve karbonat tespit edilebilmektedir. Bu yöntemle tespit edilen taş mineral içerikleri tek, iki, üç ve daha fazla komponent olarak gruplandırıldı. Elde edilen taş bileşenleri kılavuzlarda evrensel olarak sınıflandırılmış taş çeşitleri ile uygunluğu açısından kıyaslandı.Bulgular: İnceleme sonunda 65 (%32.9) örnekte tek mineral, 133 (%67.1) örnekte ise birden fazla mineral içeriği saptandı. 45 (%22.7) kalsiyum oksalat, 22 (%11.6) kalsiyum fosfat, 11 (%6.1) kalsiyum + ürik asit, 10 (%5) ürik asit, 7 (%3.5) sistin, 7 (%3.5) karbonat apatit, 4 (%2) amonyum ürat, 1 (%0.5) magnezyum amonyum fosfat olmak üzere 107 (%54) örnek EAU (European Association of Urology) kılavuzundaki taş çeşitlerinde adı geçen örneklerle uyum gösteriyordu. Ancak 91 (%46) örnekteki taş analizleri bu kılavuzda yer almayan kombinasyonlardan oluşuyordu.Sonuç: Kimyasal taş analizi literatürde belirtilen eksikliklerinin yanında taş kılavuzlarında yer alan taş tip ve bileşenlerini kategorize etmede yetersiz olarak değerlendirildi. Kimyasal yöntem özellikle ilk tanı esnasında taşın değerlendirilmesi amacıyla tercih edilecek bir yöntem gibi görünmemektedir

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Kimyasal Yöntemle Yapılan Üriner Sistem Taş Analizinin Taşı Tanımlamadaki Etkinliğinın Araştırılması

Öz:

Background: The present study evaluated use of chemical method to determine components and category of urinary stones described in current stone disease guidelines.Methods: Chemical analysis of total of 198 urinary stones was performed between March 2014 and September 2015. Calcium, oxalate, uric acid, magnesium, phosphate, cysteine, ammonium, and carbonate were among components detected in stone composition. Stones were divided into groups based on presence of 1, 2, or 3 or more components. Composition results were compared with stone composition data provided in global guidelines.Results: Sixty-five (32.9%) samples consisted of 1 mineral and 133 (67.1%) contained more than 1. Of the total, 107 (54%) compositions were included in European Association of Urology (EAU) guidelines. The 107 samples included 45 (22.7%) with components of calcium oxalate, 22 (11.6%) of calcium phosphate, 11 (6.1%) of calcium and uric acid, 10 (5%) of uric acid, 7 (3.5%) of cysteine, 7 (3.5%) of carbonate apatite, 4 (2%) of ammonium urate, and 1 (0.5%) of magnesium, ammonium, and phosphate. However, 91 (46%) stones consisted of components that are not in current EAU guidelines.Conclusion: Chemical analysis was found insufficient to categorize stone types and components seen in EAU guidelines. There is also a lack of information on the process in the literature. It was concluded that chemical analysis is not the best method to evaluate urinary stones

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	KARA Ö, MALKOÇ E, Tonyali S, ATEŞ F, UYUMAZ A, ÖZCAN Ö, AKTAŞ Z, Şenkul T (2016). Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. , 195 - 199.
Chicago	KARA Önder,MALKOÇ Ercan,Tonyali Senol,ATEŞ Ferhat,UYUMAZ Ali Serdal,ÖZCAN Ömer,AKTAŞ Zeki,Şenkul Temuçin Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. (2016): 195 - 199.
MLA	KARA Önder,MALKOÇ Ercan,Tonyali Senol,ATEŞ Ferhat,UYUMAZ Ali Serdal,ÖZCAN Ömer,AKTAŞ Zeki,Şenkul Temuçin Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. , 2016, ss.195 - 199.
AMA	KARA Ö,MALKOÇ E,Tonyali S,ATEŞ F,UYUMAZ A,ÖZCAN Ö,AKTAŞ Z,Şenkul T Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. . 2016; 195 - 199.
Vancouver	KARA Ö,MALKOÇ E,Tonyali S,ATEŞ F,UYUMAZ A,ÖZCAN Ö,AKTAŞ Z,Şenkul T Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. . 2016; 195 - 199.
IEEE	KARA Ö,MALKOÇ E,Tonyali S,ATEŞ F,UYUMAZ A,ÖZCAN Ö,AKTAŞ Z,Şenkul T "Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition." , ss.195 - 199, 2016.
ISNAD	KARA, Önder vd. "Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition". (2016), 195-199.

APA	KARA Ö, MALKOÇ E, Tonyali S, ATEŞ F, UYUMAZ A, ÖZCAN Ö, AKTAŞ Z, Şenkul T (2016). Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, 27(3), 195 - 199.
Chicago	KARA Önder,MALKOÇ Ercan,Tonyali Senol,ATEŞ Ferhat,UYUMAZ Ali Serdal,ÖZCAN Ömer,AKTAŞ Zeki,Şenkul Temuçin Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi 27, no.3 (2016): 195 - 199.
MLA	KARA Önder,MALKOÇ Ercan,Tonyali Senol,ATEŞ Ferhat,UYUMAZ Ali Serdal,ÖZCAN Ömer,AKTAŞ Zeki,Şenkul Temuçin Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, vol.27, no.3, 2016, ss.195 - 199.
AMA	KARA Ö,MALKOÇ E,Tonyali S,ATEŞ F,UYUMAZ A,ÖZCAN Ö,AKTAŞ Z,Şenkul T Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi. 2016; 27(3): 195 - 199.
Vancouver	KARA Ö,MALKOÇ E,Tonyali S,ATEŞ F,UYUMAZ A,ÖZCAN Ö,AKTAŞ Z,Şenkul T Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi. 2016; 27(3): 195 - 199.
IEEE	KARA Ö,MALKOÇ E,Tonyali S,ATEŞ F,UYUMAZ A,ÖZCAN Ö,AKTAŞ Z,Şenkul T "Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition." Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, 27, ss.195 - 199, 2016.
ISNAD	KARA, Önder vd. "Evaluation of the Efficacy of Chemical Method to Determine Urinary Tract Stone Composition". Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi 27/3 (2016), 195-199.