Yıl: 2017 Cilt: 7 Sayı: 1 Sayfa Aralığı: 9 - 16 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi

Öz:
Amaç: Bu çalıflmada alerjik rinit (AR) hastalarında psikiyatrik bozuklukların insidansı ve AR tedavisine dirençli AR hastalarının tedavi rejimine dahil edildiğinde antidepresanların etkilerini değerlendirmeyiamaçladık.Yöntem:Çalıflmaya AR tedavisine dirençli ve immünoterapi seçeneğini kabul etmeyen toplam 49 hasta alındı. Kırk hastanın 38'ine antidepresan sertralin alması önerildi. Ancak yalnızca 21'i ilacı kullanmayı kabul ederken 17'si reddetti. Antidepresana bafllamayı kabul eden21 hastaya ayrıca günde tek doz desloratadin ve intranazal mometazon furoat alması önerildi (Grup 1). Antidepresan kullanmayı reddeden hastalara AR tedavisine bafllaması önerildi (Grup 2). Tedaviden 6hafta sonra hastaların tümünde yeniden AR için semptom skorlamasıyapıldı. Bir psikiyatrist nezaretinde hastalara Psikolojik SemptomKontrol Listesi-90 (The Psychological Symptom Checklist-90; SCL90), Beck Depresyon Envanteri (Beck Depression Inventory; BDI) veAnksiyete Durum Envanteri (State-Trait Anxiety Inventory; STAI TX I ve TX II) uygulandı. Bulgular:Grup 1'de tedavi sonrası nazal ve nazal olmayan semptomskorları yedi semptomun her biri için tedavi öncesi skorlardan anlamlı derecede daha iyiydi (p=0.000). AR semptom skorlarıyla ortalamaSCL-90 genel semptom skoru, SCL-90 altölçek skorları, total BDIskorları ve STAI skorları arasında anlamlı bir korelasyon bulunmadı(p>0.05). Sonuç:AR popülasyonunda psikosomatik faktör büyük önem taflıdığından bu çalıflma antidepresan kullanımının tedaviye dirençli AR'dealerjik semptomları azalttığını akla getirmektedir.
Anahtar Kelime:

Konular: Kulak, Burun, Boğaz

Psychiatric analysis of treatment-resistant allergic rhinitis and evaluation of the effects of antidepressant use

Öz:
Objective:We evaluated the incidence of psychiatric disorders inpatients with allergic rhinitis (AR) and assessed the effects of the use ofantidepressants on symptoms when they are included in the treatmentregimen of patients with AR who are resistant to AR treatment. Methods:A total of 49 patients who were resistant to the treatment forAR and who did not accept the option of immunotherapy were included in the study. Thirty-eight of the 40 patients were advised to take theantidepressant sertraline; however, only 21 of them agreed to use themedication while 17 of them refused. The 21 patients who agreed tobegin the antidepressant were also advised to undergo AR treatmentwith desloratadine once per day and intranasal mometasone furoate onceper day (Group 1). The patients who refused to use the antidepressantwere advised to begin the AR treatment (Group 2). Symptom scoring forAR was again performed for all patients 6 weeks after treatment. ThePsychological Symptom Checklist-90 (SCL-90), Beck DepressionInventory (BDI), and State-Trait Anxiety Inventory (STAI TX I and TXII) were performed on the patients in the company of a psychiatrist. Results: The post-treatment nasal and non-nasal symptom scores inGroup 1 were significantly better than the pretreatment scores for any ofthe seven symptoms (p=0.000). No significant correlation was foundbetween the AR symptom scores and the average SCL-90 general symptom score, the SCL-90 subscale scores, the total BDI scores, and the STAIscores (p>0.05). Conclusion:This study suggests that the use of antidepressants diminishes the allergic symptoms in patients with treatment-resistant AR since psychosomatic factor is of great importance in the patient population of AR.
Anahtar Kelime:

Konular: Kulak, Burun, Boğaz
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA UÇAL Y, Tansuker H, BAKIM B, YILDIRIM Ö, SÖZEN E, COflKUN B (2017). Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. , 9 - 16.
Chicago UÇAL Yusuf Orhan,Tansuker Hasan Deniz,BAKIM BAHADIR,YILDIRIM Ömürsen,SÖZEN Esra,COflKUN Berna Uslu Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. (2017): 9 - 16.
MLA UÇAL Yusuf Orhan,Tansuker Hasan Deniz,BAKIM BAHADIR,YILDIRIM Ömürsen,SÖZEN Esra,COflKUN Berna Uslu Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. , 2017, ss.9 - 16.
AMA UÇAL Y,Tansuker H,BAKIM B,YILDIRIM Ö,SÖZEN E,COflKUN B Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. . 2017; 9 - 16.
Vancouver UÇAL Y,Tansuker H,BAKIM B,YILDIRIM Ö,SÖZEN E,COflKUN B Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. . 2017; 9 - 16.
IEEE UÇAL Y,Tansuker H,BAKIM B,YILDIRIM Ö,SÖZEN E,COflKUN B "Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi." , ss.9 - 16, 2017.
ISNAD UÇAL, Yusuf Orhan vd. "Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi". (2017), 9-16.
APA UÇAL Y, Tansuker H, BAKIM B, YILDIRIM Ö, SÖZEN E, COflKUN B (2017). Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. ENT Updates, 7(1), 9 - 16.
Chicago UÇAL Yusuf Orhan,Tansuker Hasan Deniz,BAKIM BAHADIR,YILDIRIM Ömürsen,SÖZEN Esra,COflKUN Berna Uslu Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. ENT Updates 7, no.1 (2017): 9 - 16.
MLA UÇAL Yusuf Orhan,Tansuker Hasan Deniz,BAKIM BAHADIR,YILDIRIM Ömürsen,SÖZEN Esra,COflKUN Berna Uslu Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. ENT Updates, vol.7, no.1, 2017, ss.9 - 16.
AMA UÇAL Y,Tansuker H,BAKIM B,YILDIRIM Ö,SÖZEN E,COflKUN B Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. ENT Updates. 2017; 7(1): 9 - 16.
Vancouver UÇAL Y,Tansuker H,BAKIM B,YILDIRIM Ö,SÖZEN E,COflKUN B Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi. ENT Updates. 2017; 7(1): 9 - 16.
IEEE UÇAL Y,Tansuker H,BAKIM B,YILDIRIM Ö,SÖZEN E,COflKUN B "Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi." ENT Updates, 7, ss.9 - 16, 2017.
ISNAD UÇAL, Yusuf Orhan vd. "Tedaviye dirençli alerjik rinitin psikiyatrik analizi ve antidepresan kullan>m> etkilerinin değerlendirilmesi". ENT Updates 7/1 (2017), 9-16.