Yıl: 2017 Cilt: 33 Sayı: 3 Sayfa Aralığı: 175 - 179 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Course of sepsis in rats with thyroid dysfunction

Öz:
Objective: Numerous studies show the relationship between sepsis and thyroid hormones. Virtually all these studiesinvestigate changes in post-sepsis thyroid hormones and the relationship between these changes and the progressionof the disease. Our aim in this study was to investigate the progression of sepsis in rats with thyroid dysfunction.Material and Methods: The study involved four groups, each containing seven female Wistar albino rats: Group 1:Sham, Group 2: Control (Sepsis), Group 3: Hyperthyroidism-Sepsis, and Group 4: Hypothyroidism-Sepsis. Group 1 onlyreceived laparotomy. Group 2 only had sepsis. Sepsis was induced in Group 3 and Group 4 following formation ofhyperthyroidism and hypothyroidism, respectively. After 24 hours, relaparotomy and thoracotomy were performed,and tissue and blood samples were drawn.Results: Dysfunctions seen in the liver, lungs, and kidneys during sepsis and other findings of sepsis were milder inthe hyperthyroidism group in comparison to both the control and hypothyroidism groups.Conclusion: The results of Simon’s grade, histopathological organ damage, and laboratory parameters revealed thatthe progression of sepsis was milder in the hyperthyroid group than in the hypothyroid and euthyroid groups. Theprogression in the hypothyroid group was the most severe. Therefore, the results of the study raise the question ofwhether immediate treatment in cases of hypothyroidism and slow return of thyroid function to normal levels incases of hyperthyroidism are adequate treatment approaches in patients who may develop sepsis or septic shock.”To determine the answer to this question, more detailed studies are required with a higher number of subjects.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA TAŞCI H, ERİKOĞLU M, TOY H, KARAİBRAHİMOĞLU A (2017). Course of sepsis in rats with thyroid dysfunction. , 175 - 179.
Chicago TAŞCI HALİL İBRAHİM,ERİKOĞLU Mehmet,TOY HATİCE,KARAİBRAHİMOĞLU ADNAN Course of sepsis in rats with thyroid dysfunction. (2017): 175 - 179.
MLA TAŞCI HALİL İBRAHİM,ERİKOĞLU Mehmet,TOY HATİCE,KARAİBRAHİMOĞLU ADNAN Course of sepsis in rats with thyroid dysfunction. , 2017, ss.175 - 179.
AMA TAŞCI H,ERİKOĞLU M,TOY H,KARAİBRAHİMOĞLU A Course of sepsis in rats with thyroid dysfunction. . 2017; 175 - 179.
Vancouver TAŞCI H,ERİKOĞLU M,TOY H,KARAİBRAHİMOĞLU A Course of sepsis in rats with thyroid dysfunction. . 2017; 175 - 179.
IEEE TAŞCI H,ERİKOĞLU M,TOY H,KARAİBRAHİMOĞLU A "Course of sepsis in rats with thyroid dysfunction." , ss.175 - 179, 2017.
ISNAD TAŞCI, HALİL İBRAHİM vd. "Course of sepsis in rats with thyroid dysfunction". (2017), 175-179.
APA TAŞCI H, ERİKOĞLU M, TOY H, KARAİBRAHİMOĞLU A (2017). Course of sepsis in rats with thyroid dysfunction. Turkish Journal of Surgery, 33(3), 175 - 179.
Chicago TAŞCI HALİL İBRAHİM,ERİKOĞLU Mehmet,TOY HATİCE,KARAİBRAHİMOĞLU ADNAN Course of sepsis in rats with thyroid dysfunction. Turkish Journal of Surgery 33, no.3 (2017): 175 - 179.
MLA TAŞCI HALİL İBRAHİM,ERİKOĞLU Mehmet,TOY HATİCE,KARAİBRAHİMOĞLU ADNAN Course of sepsis in rats with thyroid dysfunction. Turkish Journal of Surgery, vol.33, no.3, 2017, ss.175 - 179.
AMA TAŞCI H,ERİKOĞLU M,TOY H,KARAİBRAHİMOĞLU A Course of sepsis in rats with thyroid dysfunction. Turkish Journal of Surgery. 2017; 33(3): 175 - 179.
Vancouver TAŞCI H,ERİKOĞLU M,TOY H,KARAİBRAHİMOĞLU A Course of sepsis in rats with thyroid dysfunction. Turkish Journal of Surgery. 2017; 33(3): 175 - 179.
IEEE TAŞCI H,ERİKOĞLU M,TOY H,KARAİBRAHİMOĞLU A "Course of sepsis in rats with thyroid dysfunction." Turkish Journal of Surgery, 33, ss.175 - 179, 2017.
ISNAD TAŞCI, HALİL İBRAHİM vd. "Course of sepsis in rats with thyroid dysfunction". Turkish Journal of Surgery 33/3 (2017), 175-179.