EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS

OZER, TAHA; AKTAS, ALPER; Karahan, Siyami

EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS

Taha ÖZER, (Hacettepe Üniversitesi)

Alper AKTAŞ, (Hacettepe Üniversitesi)

Siyami KARAHAN (Kırıkkale Üniversitesi)

Clinical Dentistry and Research

1 0

Yıl: 2019 Cilt: 43 Sayı: 1 Sayfa Aralığı: 3 - 10 Metin Dili: İngilizce İndeks Tarihi: 20-01-2020

EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS

Öz:

Background and Aim: To evaluate the effects of AnkaferdBlood Stopper added platelet-rich fibrin administered incranial bone defects created in rabbits via histomorphometricassessment.Materials and Method: Four circular 5 mm defects werecreated in the crania of 16 New Zealand rabbits. Each defect ineach animal received one of four treatments: no treatment (ECgroup), platelet-rich fibrin administration (PRF group), AnkaferdBlood Stopper added platelet-rich fibrin administration(PRF + ABS group) and collagen membrane administration (CMgroup). Histomorphometric assessment was conducted at 4and 8 weeks after surgery.Results: Between-group comparisons of the new bone arearevealed significant differences between the PRF + ABS groupand the remaining three groups at 4 weeks. The new bonearea was significantly larger at 8 weeks than at 4 weeks in allgroups.Conclusion: The use of Ankaferd Blood Stopper in conjunctionwith platelet-rich fibrin improves bone healing, strengthens themembrane property of platelet-rich fibrin and promotes betterossification.

Anahtar Kelime:

Konular: Diş Hekimliği

ANKAFERD BLOOD STOPPER İLE GÜÇLENDİRİLMİŞ PLATELETTEN ZENGİN FİBRİN MEMBRANIN DENEYSEL KEMİK DEFEKTLERİNDE YÖNLENDİRİLMİŞ DOKU REJENERASYONU ÜZERİNE ETKİLERİ

Öz:

Amaç: Ankaferd Blood Stopper ile güçlendirilmiş trombositten zengin fibrinin tavşanlar üzerinde oluşturulan kalvaryal kemik defektleri üzerindeki etkilerinin histomorfometrik yöntemler ile değerlendirmek. Gereç ve Yöntem: 16 Yeni Zelanda tavşanı kafatasında, dörder adet 5 mm çapında dairesel kemik defekti oluşturuldu. Her bir hayvandaki dört farklı defekt bölgesine, dört farklı tedaviden biri uygulandı: tedavi yok (EC grubu), trombositten zengin fibrin uygulaması (PRF grubu), Ankaferd Blood Stopper ile beraber trombositten zengin fibrin uygulaması (PRF + ABS grubu) ve kolajen membran uygulaması (CM grubu). Histomorfometrik değerlendirme cerrahiden 4 ve 8 hafta sonra yapıldı. Bulgular: Yeni kemik alanının gruplar arası karşılaştırmalarında, 4.hafta örneklerinde PRF + ABS grubu ile kalan üç grup arasında anlamlı fark olduğu görüldü. Yeni kemik alanının, tüm gruplarda 8.hafta örneklerinde, 4.hafta örneklerine göre anlamlı derecede yüksek olduğu görüldü. Sonuç: Ankaferd Blood Stopper’ın trombositten zengin fibrin ile birlikte kullanılması; kemik iyileşmesini arttırmakta, trombositten zengin fibrinin membran özelliğini güçlendirmekte ve daha iyi bir kemikleşme sağlamaktadır.

Anahtar Kelime:

Konular: Diş Hekimliği

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	OZER T, AKTAS A, Karahan S (2019). EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. , 3 - 10.
Chicago	OZER TAHA,AKTAS ALPER,Karahan Siyami EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. (2019): 3 - 10.
MLA	OZER TAHA,AKTAS ALPER,Karahan Siyami EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. , 2019, ss.3 - 10.
AMA	OZER T,AKTAS A,Karahan S EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. . 2019; 3 - 10.
Vancouver	OZER T,AKTAS A,Karahan S EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. . 2019; 3 - 10.
IEEE	OZER T,AKTAS A,Karahan S "EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS." , ss.3 - 10, 2019.
ISNAD	OZER, TAHA vd. "EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS". (2019), 3-10.

APA	OZER T, AKTAS A, Karahan S (2019). EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. Clinical Dentistry and Research, 43(1), 3 - 10.
Chicago	OZER TAHA,AKTAS ALPER,Karahan Siyami EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. Clinical Dentistry and Research 43, no.1 (2019): 3 - 10.
MLA	OZER TAHA,AKTAS ALPER,Karahan Siyami EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. Clinical Dentistry and Research, vol.43, no.1, 2019, ss.3 - 10.
AMA	OZER T,AKTAS A,Karahan S EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. Clinical Dentistry and Research. 2019; 43(1): 3 - 10.
Vancouver	OZER T,AKTAS A,Karahan S EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. Clinical Dentistry and Research. 2019; 43(1): 3 - 10.
IEEE	OZER T,AKTAS A,Karahan S "EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS." Clinical Dentistry and Research, 43, ss.3 - 10, 2019.
ISNAD	OZER, TAHA vd. "EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS". Clinical Dentistry and Research 43/1 (2019), 3-10.