Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment

Selmi YILMAZ, (Akdeniz Üniversitesi)
Melda MISIRLIOĞLU (Kırıkkale Üniversitesi)
Akdeniz Tıp Dergisi
3 0
Yıl: 2019 Cilt: 5 Sayı: 2 Sayfa Aralığı: 358 - 364 Metin Dili: İngilizce DOI: 10.17954/amj.2019.1366 İndeks Tarihi: 26-11-2019

Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment

Öz:
Objective: The aim of this study was to investigate the effects of the novel Nociceptive TrigeminalInhibition Tension Suppression System (NTI-tss) splint therapy in bruxism patients based on the viewthat the etiology is derived from central nerveous system. It was also aimed to evaluate the differencesin cortical activity between bruxism patients and healthy subjects during the clenching function.Material and Methods: A total of 30 volunteers (15 bruxist and 15 healthy) attending theKırıkkaleUniversity Faculty of Dentistry for various dental reasons were included in the study. For thediagnosis of bruxism, the criteria determined by an international consensus in 2013 were used. Brainactivity was examined by functional magnetic resonance imaging during tooth clenching and rest tasksfor each participant with the BrainVoyager QX 2.8 statistical data analysis program. This protocolwas approved by the ethics committee of the medical faculty of Kırıkkale University, Turkey (02/04).Results: When the average rate of brain activity in healthy subjects and bruxism patients wascompared, hypoactivation was observed during the clenching task in the inferior parietal lobe(Brodmann 39 ve 40) and dorsal posterior cingulate area (Brodmann 31). The group analysis betweenpre- and post- treatment groups revealed one activation cluster in the post-treatment group that mayindicate increased activation in the mentioned cortical areas after 11 nights of NTI-tss splint therapy.When control group compared with post- treatment group no differences observed.Conclusion: With the aid of a neuroimaging technique, the decrease in activation in certain areasof the cerebral cortex in patients with bruxism. Our findings indicate that wearing the NTI-tss splintfor 11 nights increased BOLD in the mentioned cortical area. These results might improve theunderstanding and physiological handling of sleep bruxism.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Bruksizm Hastalarında Splint Tedavisinin Serebral Gösterimi; Bir Fonsiyonel Manyetik Rezonans Görüntüleme Deneyi

Öz:
Amaç: Çalışmanın amacı bruksimin etiyolojisinin santral sinir sistemi kaynaklı olduğu görüşünden yola çıkarak Nociceptive Trigeminal Inhibition Tension Suppression System (NTI-tss) okluzal splint tedavisinin beyin merkezlerinde meydana getireceği olası değişiklikleri gözlemlemektir. Ayrıca bruksizmi olan hastalar ve sağlıklı bireyler arasında diş sıkma fonksiyonu sırasında kortekste oluşan aktivite farklarının değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya Kırıkkale Üniversitesi Diş Hekimliği Fakültesi Ağız Diş ve Çene Radyolojisi Anabilim Dalına çeşitli şikayetlerle başvuran 15 bruksizmi olan ve 15 bruksizmi olmayan (kontrol grubu) toplam 30 birey katılmıştır. Bruksizm varlığının belirlenmesinde 2013 yılında uluslar arası otörler tarafından düzenlenen kriterler kullanılmıştır. Her katılımcı için diş sıkma ve dinlenme görevleri sırasında fonksiyonel manyetik rezonans görüntüleme ile beyin aktivitesi incelendi. Data analizi için BrainVoyager QX 2.8 programı kullanılmıştır. Bu proje Kırıkkale Üniversitesi Etik kurulu (Karar no: 02/04) tarafından onaylanmıştır. Bulgular: Sağlıklı bireyler ile bruksizmi olanlar arası diş sıkma görevi sırasında beyinde meydana gelen aktivasyon ortalaması karşılaştırıldığında bruksizm grubunda inferior parietal lob (Brodmann 39 ve 40) ve dorsal posterior cingulate area (Brodmann 31) bölgelerinde hipoaktivasyon gözlenmiştir. Splint kullanımı öncesi ve sonrası gruplar analiz edildiğinde 11 günlük splint kullanımı sonrasında aktivitede artış kümesi izlendi; kontrol grubu ile bruksizm grubu arasında anlamlı bir fark bulunmamıştır. Sonuç: Bir nörogörüntüleme tekniği olan fMRI tekniği yardımı ile bruksizm hastalarında serebral korteksin belirli bölgelerinde aktivasyonda azalma izlenmiştir. 11 günlük splint kullanımının bu bölgelerde BOLD sinyalini artırdığı saptandı. Bu çalışmanın bulgularının bruksizmin etiyolojisi ve etkin tedavisinin netleşmesine yardım edeceğini düşünmekteyiz.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Yardımcı S, Misirlioglu M (2019). Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. , 358 - 364. 10.17954/amj.2019.1366
Chicago Yardımcı Selmi,Misirlioglu Melda Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. (2019): 358 - 364. 10.17954/amj.2019.1366
MLA Yardımcı Selmi,Misirlioglu Melda Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. , 2019, ss.358 - 364. 10.17954/amj.2019.1366
AMA Yardımcı S,Misirlioglu M Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. . 2019; 358 - 364. 10.17954/amj.2019.1366
Vancouver Yardımcı S,Misirlioglu M Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. . 2019; 358 - 364. 10.17954/amj.2019.1366
IEEE Yardımcı S,Misirlioglu M "Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment." , ss.358 - 364, 2019. 10.17954/amj.2019.1366
ISNAD Yardımcı, Selmi - Misirlioglu, Melda. "Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment". (2019), 358-364. https://doi.org/10.17954/amj.2019.1366
APA Yardımcı S, Misirlioglu M (2019). Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. Akdeniz Tıp Dergisi, 5(2), 358 - 364. 10.17954/amj.2019.1366
Chicago Yardımcı Selmi,Misirlioglu Melda Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. Akdeniz Tıp Dergisi 5, no.2 (2019): 358 - 364. 10.17954/amj.2019.1366
MLA Yardımcı Selmi,Misirlioglu Melda Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. Akdeniz Tıp Dergisi, vol.5, no.2, 2019, ss.358 - 364. 10.17954/amj.2019.1366
AMA Yardımcı S,Misirlioglu M Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. Akdeniz Tıp Dergisi. 2019; 5(2): 358 - 364. 10.17954/amj.2019.1366
Vancouver Yardımcı S,Misirlioglu M Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment. Akdeniz Tıp Dergisi. 2019; 5(2): 358 - 364. 10.17954/amj.2019.1366
IEEE Yardımcı S,Misirlioglu M "Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment." Akdeniz Tıp Dergisi, 5, ss.358 - 364, 2019. 10.17954/amj.2019.1366
ISNAD Yardımcı, Selmi - Misirlioglu, Melda. "Cerebral Representation of Splint Therapy in Bruxism Patients; An Functional Magnetic Resonance Imaging Experiment". Akdeniz Tıp Dergisi 5/2 (2019), 358-364. https://doi.org/10.17954/amj.2019.1366
Sayfa Oluşturulma Tarihi
23-04-2024 9:24

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