What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey

Yıl: 2020 Cilt: 14 Sayı: 2 Sayfa Aralığı: 329 - 344 Metin Dili: İngilizce DOI: 10.21763/tjfmpc.729917 İndeks Tarihi: 17-06-2020

What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey

Öz:
Coronaviruses (CoVs) belong to the subfamily Orthocoronavirinae, which includes α‐coronavirus, β-coronavirus, γ‐coronavirus, and δcoronavirus in the order Nidovirales in the Coronaviridae family. While coronaviruses cause enzootic infections primarily in birds andmammals, in the recent years, it has been shown to be capable of infecting humans as well. In the last days of 2019, China's World HealthOrganization (WHO) Country Office reported thecases of pneumonia of unknown etiology from Wuhan City, Hubei Province. Thecausative agent was isolated on January 7, 2020, and was identified as a new type of coronavirus. At the end of 2019, a new coronavirusoutbreak, now known as SARS-CoV-2 (2019), was announced by the World Health Organization on January 31, 2020 as an urgent publichealth problem. In this review article, what we have learned about the new corona virus pandemic, the situation in Turkey and currentapproaches in diagnosis and treatment were discussed.
Anahtar Kelime:

Yeni Koronavirüs Pandemisi ile İlgili Öğrendiklerimiz, Tanı ve Tedavisindeki Güncel Yaklaşımlar ve Türkiye’deki Durum

Öz:
Koronavirüsler (CoV'ler), Coronaviridae familyasındaki Nidovirales düzenindeki α‐coronavirus, β‐coronavirus, γ‐coronavirus, and δcoronavirus'u içeren Orthocoronavirinae alt familyasına aittir. Koronavirüsler öncelikle kuşlarda ve memelilerde enzootik enfeksiyonlara neden olurken son yıllarda insanları da enfekte ettiği görülmüştür. 2019'un son günlerinde, Çin'in Dünya Sağlık Örgütü (DSÖ) Ülke Ofisi tarafından Hubei Eyaleti, Wuhan Şehrinden etiyolojisi bilinmeyen pnömoni vakalarının rapor edildiği bildirilmiştir. Etken ajan 7 Ocak 2020'de izole edilmiş ve yeni bir tip koronavirüs olarak tanımlanmıştır. 2019'un sonunda, şimdi SARS-CoV-2 (2019) olarak bilinen yeni bir koronavirüs salgını Dünya Sağlık Örgütü tarafından 31 Ocak 2020'de uluslararası endişe duyulan acil bir halk sağlığı problemi olarak açıklanmıştır. Bu derleme yazısında yeni koronavirüs pandemisi ile ilgili öğrendiklerimiz, tanı ve tedavisindeki güncel yaklaşımlar ve Türkiye’deki durum tartışılmıştır.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
  • 1. Sifuentes-Rodríguez E, Palacios-Reyes D. COVID-19: The outbreak caused by a new coronavirus. Bol Med Hosp Infant Mex. 2020;77(2):47-53. doi:10.24875/BMHIM.20000039
  • 2. Tan W, Zhao X, Ma X, Wang W, Niu P, Xu W. et al. Notes from the Field: A novel coronavirus genome identified in a cluster of pneumonia cases–Wuhan, China 2019−2020. China CDC Weekly 2020; 2: 61-62.
  • 3. Wu F, Zhao S, Yu B, Chen YM, Wang W, Song ZG, et al. A new coronavirus associated with human respiratory disease in China. Nature. 2020 Mar;579(7798):265-269. doi: 10.1038/s41586-020-2008-3. Epub 2020 Feb 3.PMID: 32015508.
  • 4. Kannan S, Shaik Syed Ali P, Sheeza A, Hemalatha K. COVID-19 (Novel Coronavirus 2019) - recent trends. Eur Rev Med Pharmacol Sci. 2020 Feb;24(4):2006-2011. doi: 10.26355/eurrev_202002_20378.PMID: 32141569
  • 5. World Health Organization (2020). WHO characterizes COVID-19 as a pandemic [online] Website https://www.who.int/emergencies/diseases/novelcoronavirus-2019/events-asthey-happen [accessed 29 March 2020].
  • 6. WHO. Middle East respiratory syndrome coronavirus (MERS-CoV). November, 2019. http://www.who.int/emergencies/merscov/en/(accessed Jan 19, 2020).
  • 7. Fung TS, Liu DX. Human coronavirus: hostpathogen interaction. Annual Review of Microbiology 2019; 73: 529-557. doi: 10.1146/annurev-micro-020518-115759.
  • 8. T.C. Sağlık Bakanlığı (2020). COVID-19 (SARS-CoV-2 Enfeksiyonu) Rehberi (Bilim Kurulu Çalışması) [online]. Website https://covid19bilgi.saglik.gov.tr/depo/rehberler/C OVID-19_Rehberi.pdf [accessed 20 April 2020].
  • 9. T.C. Sağlık Bakanlığı (2020). Türkiye’deki Güncel Durum [online]. https://covid19bilgi.saglik.gov.tr/tr/gunlukvaka.ht ml [accessed 13 April 2020].
  • 10. Koçak-Tufan Z, Kayaaslan B. Crushing the Curve, the Role of National and International Institutions and Policy Makers in COVID-19 Pandemic. Turk J Med Sci. 2020 Apr 21;50(SI1):495-508. doi: 10.3906/sag-2004-167.
  • 11. World Health Organization (2020). Who we are [online]. Website https://www.who.int/about/who-we-are [accessed 13 April 2020].
  • 12. World Health Organization (2020). Novel Coronavirus (2019-nCoV) Situation Report - 10 [online]. Website https://www.who.int/docs/defaultsource/coronaviruse/situation-reports/20200130- sitrep-10-ncov.pdf?sfvrsn=d0b2e480_2 [accessed 30 January 2020].
  • 13. World Health Organization (2020). Coronavirus disease (COVID-19) outbreak [online]. Website https://www.who.int/westernpacific/emergencies/c ovid-19 [accessed 13 April 2020].
  • 14. World Health Organization (2020). WHO Statement regarding cluster of pneumonia cases in Wuhan, China [online]. Website https://
  • 15. World Health Organization (2020). COVID‐19 strategy update - 14 April 2020 https://www.who.int/docs/defaultsource/coronaviruse/covid-strategy-update14april2020.pdf?sfvrsn=29da3ba0_19&download =true [accessed 24 April 2020].
  • 16. World Health Organization. Global Surveillance for human infection with coronavirus disease (COVID-19): interim guidance, https://www.who.int/publications-detail/globalsurveillance-for-human-infection-with-novelcoronavirus-(2019-ncov) [accessed 20 April 2020].
  • 17. Centers for Disease Control and Prevention (2020). Past pandemics [online]. Website https://www.cdc.gov/flu/pandemicresources/basics/past-pandemics.html [accessed 15 April 2020].
  • 18. CDC (2020). Coronavirus disease 2019 (COVİD-19) Recommendation Regarding the Use of Cloth Face Coverings, Especially in Areas of Significant Community-Based Transmission [online]. Website https://www.cdc.gov/coronavirus/2019- ncov/prevent-gettingsick/cloth-face-cover.html [accessed 3 April 2020].
  • 19. Cheng JL, Huang C, Zhang GJ, Liu DW, Li P, Lu CY, et al. Epidemiological characteristics of novel coronavirus pneumonia in Henan. Zhonghua Jie He He Hu Xi Za Zhi. 2020 Mar 2;43(0):E027.
  • 20. Rothana HA, Byrareddyb SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020;109:102433. doi: 10.1016/j.jaut.2020.102433. Epub 2020 Feb 26.
  • 21. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; 579 (7798): 270-273. doi: 10.1038/s41586-020-2012-7.
  • 22. Lu R, Zhao X, Li J, Niu P, B. Yang B, Wu H, et al., Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding, Lancet 395 (10224) (2020) 565–574, https://doi.org/10.1016/S0140- 6736(20)30251-8.
  • 23. Bulut C, Kato Y. Epidemiology of COVID-19. Turk J Med Sci (2020) 50:563-570.
  • 24. van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. N Engl J Med. 2020 Apr 16;382(16):1564-1567.
  • 25. Guo ZD, Wang ZY, Zhang SF, Li X, Li L, Li C, et al. Aerosol and surface distribution of severe acute respiratory syndrome coronavirus 2 in hospital wards, Wuhan, China, 2020. Emerging Infectious Diseases 2020; 26 (7) [Epub ahead of print]. doi: 10.3201/eid2607.200885.
  • 26. Wang W, Xu Y, Gao R, Lu R, Han K, Wu G, et al. Detection of SARS-CoV-2 in Different Types of Clinical Specimens. JAMA. 2020 Mar 11:e203786. doi: 10.1001/jama.2020.3786
  • 27. Wu Y, Gou C, Tang L, Hong Z, Zhou J, Dong X, et al. Prolonged presence of SARS-CoV-2 viral RNA in faecal samples. Lancet Gastroenterology and Hepatolology 2020; (5): 434-435. doi: 10.1016/S2468-1253(20)30083-2
  • 28. Schwartz DA. An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes. Archives of Pathology and Laboratory Medicine 2020; March 17, [Epub ahead of print]. doi: 10.5858/arpa.2020-0901-SA.
  • 29. Backer JA, Klinkenberg D, Wallinga J. The incubation period of 2019-nCoV infections among travellers from Wuhan, China. MedRxiv 2020. doi: dx.doi.org/10.1101/2020.01.27.20018986.
  • 30. Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. The New England Journal of Medicine 2020; 382(13): 1199-1207. doi:10.1056/NEJMoa2001316
  • 31. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. The New England Journal of Medicine 2020; NEJMoa2002032. doi: 10.1056/NEJMoa2002032.
  • 32. Lauer SA, Grantz KH, Bi Q, Jones FK, Zheng Q, Meredith HR, et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Annals of Internal Medicine 2020; March 10. doi:10.7326/M20-0504.
  • 33. Jiang X, Rayner S, Luo MH. Does SARSCoV-2 has a longer incubation period than SARS and MERS? Journal of Medical Virology 2020; 92 (5): 476-478. doi: 10.1002/jmv.25708.
  • 34. Du Z, Xu X, Wu Y, Wang L, Cowling BJ, Meyers LA. Serial interval of COVID-19 among publicly reported confirmed cases. Emerging Infectious Diseases 2020; 26 (6). doi: 10.3201/eid2606.200357.
  • 35. Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z. Epidemiology of COVID-19 among children in China. Pediatrics 2020; 145 (4):e20200702. doi: 10.1542/peds.2020-0702.
  • 36. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 Cases from the Chinese Center for Disease Control and Prevention. JAMA 2020; 323(13): 1239-1242. doi:10.1001/jama.2020.2648.
  • 37. Li Q, Guan X, Wu P, Wang X, L. Zhou L, Tong Y, et al., Early transmission dynamics in wuhan, China, of novel coronavirus-infected pneumonia, N. Engl. J. Med.(2020), https://doi.org/10.1056/NEJMoa2001316.
  • 38. Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China, J. Med. Virol. 92 (4) (2020) 441–447, https://doi.org/10.1002/jmv.25689.
  • 39. Yoon SH, Lee KH, Kim JY, Lee YK, Ko H, Kim KH, et al. Chest Radiographic and CT Findings of the 2019 Novel Coronavirus Disease (COVID-19): Analysis of Nine Patients Treated in Korea. Korean J Radiol. 2020 Apr;21(4):494-500. doi: 10.3348/kjr.2020.0132. Epub 2019 Feb 26.
  • 40. Lei J, Li J, Li X, Qi X, CT imaging of the 2019 novel coronavirus (2019-nCoV) pneumonia, Radiology (2020) 200236, https://doi.org/10.1148/radiol.2020200236.
  • 41. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al., Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet 395 (10223) (2020) 497–506, https://doi.org/10.1016/S0140- 6736(20)30183-5.
  • 42. Jin YH, Cai L, Cheng ZS, Cheng H, Deng T, Fan YP, et al., A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version), Mil. Med. Res. 7 (2020) 4.
  • 43. Singhal T. A Review of Coronavirus Disease-2019 (COVID-19). The Indian Journal of Pediatrics (April 2020) 87(4):281–286 https://doi.org/10.1007/s12098-020-03263-6.
  • 44. Centers for Disease Control and Prevention, 2019 Novel Coronavirus, (2020) https://www.cdc.gov/coronavirus/2019- ncov/about/transmission.html.
  • 45. Zhao JP, Hu Y, Du RH, Chen ZS, Jin Y, Zhou M, et al. Expert consensus on the use of corticosteroid in patients with 2019-nCoV pneumonia. Zhonghua Jie He He Hu Xi Za Zhi. 2020;43:E007.
  • 46. Zhang L, Liu Y. Potential interventions for novel coronavirus in China: a systemic review. J Med Virol. 2020. https://doi.org/10.1002/jmv.25707.
  • 47. Yan Y, Zou Z, Sun Y, Li X, Xu KF, Wei Y, et al. Antimalaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model. Cell Res. 2013;23:300-302.
  • 48. Savarino A, Boelaert JR, Cassone A, Majori G, Cauda R. Effects of chloroquine on viral infections: an old drug against today’s diseases? Lancet Infect. Dis. 2003;3:722-727.
  • 49. Ahn DG, Shin HJ, Kim MH, Lee S, Kim HS, Myoung J, et al. Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19). J Microbiol Biotechnol 2020 Mar 28;30(3):313-324. doi: 10.4014/jmb.2003.03011.
  • 50. Guarner J. Three emerging coronaviruses in two decades. Am. J. Clin. Pathol. 2020;153:420- 421.
  • 51. Petersen E, Gökengin D. SARS-CoV-2 epidemiology and control, different scenarios for Turkey. Turk J Med Sci (2020) 50: 509-514.
APA Kutlu R (2020). What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. , 329 - 344. 10.21763/tjfmpc.729917
Chicago Kutlu Ruhusen What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. (2020): 329 - 344. 10.21763/tjfmpc.729917
MLA Kutlu Ruhusen What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. , 2020, ss.329 - 344. 10.21763/tjfmpc.729917
AMA Kutlu R What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. . 2020; 329 - 344. 10.21763/tjfmpc.729917
Vancouver Kutlu R What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. . 2020; 329 - 344. 10.21763/tjfmpc.729917
IEEE Kutlu R "What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey." , ss.329 - 344, 2020. 10.21763/tjfmpc.729917
ISNAD Kutlu, Ruhusen. "What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey". (2020), 329-344. https://doi.org/10.21763/tjfmpc.729917
APA Kutlu R (2020). What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. Turkish Journal of Family Medicine and Primary Care, 14(2), 329 - 344. 10.21763/tjfmpc.729917
Chicago Kutlu Ruhusen What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. Turkish Journal of Family Medicine and Primary Care 14, no.2 (2020): 329 - 344. 10.21763/tjfmpc.729917
MLA Kutlu Ruhusen What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. Turkish Journal of Family Medicine and Primary Care, vol.14, no.2, 2020, ss.329 - 344. 10.21763/tjfmpc.729917
AMA Kutlu R What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. Turkish Journal of Family Medicine and Primary Care. 2020; 14(2): 329 - 344. 10.21763/tjfmpc.729917
Vancouver Kutlu R What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey. Turkish Journal of Family Medicine and Primary Care. 2020; 14(2): 329 - 344. 10.21763/tjfmpc.729917
IEEE Kutlu R "What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey." Turkish Journal of Family Medicine and Primary Care, 14, ss.329 - 344, 2020. 10.21763/tjfmpc.729917
ISNAD Kutlu, Ruhusen. "What We Have Learned About The New Coronavirus Pandemic, Current Diagnostic and Therapeutic Approaches and The Situation in Turkey". Turkish Journal of Family Medicine and Primary Care 14/2 (2020), 329-344. https://doi.org/10.21763/tjfmpc.729917