Bilateral facial paralysis is an extremely rare clinical entity. It most often appears a special finding in a symptom complex of a systemic disease; many of them are potentially life-threatening. Failure to diagnose and treat at an early stage can have adverse clinical outcomes, and therefore clinicians should be aware of the differential diagnosis when evaluating a case. Lyme disease, Guillain-Barre syndrome, Bell’s palsy, leukemia, sarcoidosis, bacterial menengitis, syphilis, leprosy, Moebius syndrome, infectious mononucleosis, and skull fracture are the most common causes of bilateral facial paralysis. A 55 years old man suffering from fatiguability, myalgia and ear pain since one month, has delivered peripheral facial paralysis after six days in addition to mentioned symptoms first on the right then on the left side. Specific antibody positivity against Borrelia burgdorferi was measured in the patient’s serum, in addition to a tick-bite history. Our case diagnosed Lyme disease was begun amoxicilline therapy and in a short-time, his symptoms relieved. Through this case, we wanted to notice Lyme disease that is one of the causes of bilateral facial paralysis and to emphasize the necessity to ascertain ‘’ a tick-bite,, history and to search the specific antibodies against Borrelia burgdorferi in such cases.