The main purpose of this project is to examine the level of knowledge and attitudes of university students about infertility and the variables that can affect the knowledge level and attitudes, and development and evaluation of infertility prevention psycho-education program based on the information obtained, and the development and examine the effectiveness of the online infertility prevention education program in terms of ensuring mass information sharing. The Attitudes toward Infertility Scale (ATIS) and the Infertility Knowledge Test (IKT) were developed in accordance with the purpose of the project. Validity and reliability studies were conducted in two stages. In the first stage, data were collected from 443 university students and item analysis, exploratory factor analysis (EFA) and t-test for the difference between the upper and lower groups were performed, Cronbach alpha reliability coefficient and item-total score correlations were calculated for the ATIS, and the mean difficulty of the test and the KR-20 reliability coefficient were calculated for the IKT. In the second stage, confirmatory factor analysis (CFA) was conducted for the ATIS with data obtained from 309 college students and the Cronbach alpha reliability coefficient was calculated. After these analyzes, it was determined that both measurement instruments had sufficient validity and reliability values. In order to examine the level of knowledge and attitudes of university students about infertility and the variables that can affect their level of knowledge and attitudes; IKT, ATIS, Personal Information form and needs analysis questionnaire were applied to 9693 undergraduate students (5002 females and 4691 males) attending to 21 state universities. Findings show that university students' attitudes towards infertility were relatively positive although the infertility knowledge levels were low. Furthermore, the level of knowledge and attitudes of university students about infertility showed significant differences in terms of gender, taking sexual health education, sexual relationship experience, the existence of an infertile individual in the social network, plans about having a child, caffeine consumption, alcohol use, and body mass index variables. The infertility prevention psycho-education program was prepared as nine sessions based on the data obtained from the needs analysis and literature review. The pilot study was carried out with 16 subjects. The pilot study of the infertility prevention psycho-education program was assessed by session evaluation forms that were applied after each session and by a semistructured interview and focus group interview after the program. After the assessments carried out, it was decided to increase session numbers and finally ten session infertility prevention psycho-education program was applied, and Solomon four-group design was used to examine the effectiveness of the program. As a result of the 2x2 ANOVA, it was determined that the ATIS and IKT mean scores of the subjects in the experimental group increased statistically. However, nosignificant increase was found in terms of decision-making skills and the refusal skills scores. Qualitative findings also suggested that the participants' opinions about the infertility prevention psycho-education program were considerably positive. An experimental design with pre-test post-test control group was conducted to examine the effectiveness of the online infertility prevention education program. During the four-week education sessions while the online education program - based on the blended learning approach - was conducted in the experimental group, face-to-face education was performed to the control group. As a result of the analyzes performed, it was determined that the IKT mean scores of the subjects increased in the experimental group but there was no statistically significant difference in terms of the ATIS mean scores. The findings obtained from the project were discussed with a holistic perspective taking into account the limitations of the study. The findings obtained from the project have been discussed with a holistic perspective taking into account the limitations of the study.