Objective: To evaluate perinatal outcomes in human immunodeficiency virus (HIV) infected pregnant women in Turkey.Material and Methods: Maternal characteristics, pregnancy complications, laboratory findings including HIV load, CD4 cell count, CD4/CD8ratio, neonatal features and final HIV status of the baby were retrospectively analyzed.Results: The sample included 26 singleton pregnancies, from 25 HIV-infected women. The ethnicities were Turkish (n=18), East European(n=4), Asian (n=2) and African (n=2). The majority (76.9%) was aware of their HIV status before becoming pregnant. Four cases (15.3%) werediagnosed during pregnancy and two (7.8%) at the onset of labor. The results for median HIV viral load, CD4 count, and CD4/CD8 ratio at birthwere 20 copies/mL (0-34 587), 577/mm3 (115-977), and 0.7 (0.1-1.9), respectively. The HIV viral load rate was 5.5% in eighteen women takinganti-retroviral treatment. The rates of gestational diabetes mellitus, gestational hypertension, intrauterine growth restriction, and preterm deliverywere 3.8%, 3.8%, 7.6%, and 8% (numbers are 1;1;2;2), respectively. The mean gestational week at birth was 38 weeks and mean birthweight is2972±329 g. Two babies were congenitally infected with HIV (infection rate of 8.3%). There was one needle-related accident during surgery.Conclusion: Timely diagnosis of HIV infection during pregnancy is important for preventing mother to child transmission. HIV infected womenmay give birth to HIV negative babies with the help of a multidisciplinary team, composed of perinatology, infectious diseases, and pediatricsspecialists. (J Turk Ger Gynecol Assoc 2020; 21: 180-6)
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OBJECTIVE: Hysterectomy is the most frequently performed major surgery and is the most common major abdominal operation following cesarean section. The most common indication is uterine leiomyoma. The objective of this study is to evaluate the abdominal hysterectomy indications, intraoperative and postoperative complications and surgical morbidity. STUDY DESIGN: Demographic information, surgical indications, intraoperative and postoperative complications, hospitalization periods and clinical follow-up information of the patients who underwent abdominal hysterectomy at Hacettepe University Hospital, Department of Obstetrics and Gynecology between 2000 and 2004 were retrieved from patients’ files and follow-up forms. Statistical evaluations were performed using SPSS 10.0 for Windows program and p<0.05 values were considered as statistically significant. RESULTS: Among 902 patients in whom abdominal hysterectomy was performed the mean age was 47.9 (range: 30-77), and the most common hysterectomy indication was uterine leiomyoma (n=552, 61.2%). While abdominal hysterectomy alone was performed in only 87 patients (9.6%), bilateral salphingo-oophorectomy was added in 746 patients (82.7%) and unilateral salphingo-oophorectomy was performed in 69 patients (7.7%) together with hysterectomy. Among patients in whom bilateral salphingooophorectomy was performed, 569 (76.3%) were in pre-menopausal period. In 119 patients (13.2%) an additional surgical intervention was applied during operation. Burch procedure and appendectomy were performed in 5.5% and 3.8% of patients, respectively. Mean operation time was 1.21 hours and mean hospitalization period was 6.28 days. Intraoperative complication rate was 0.6% and visceral organ injury was the most commonly seen complication. Postoperative complications were seen in 17.1% of the patients and the most frequent postoperative complications were febrile morbidity and wound infection (10.1% and 4.3%, respectively). Preoperative and postoperative mean hemoglobin values were 11.9 and 10.3 gr/dL, respectively, and 7.5% of the patients received erythrocyte transfusion postoperatively. No operation related deaths were observed during the study period. CONCLUSION: Abdominal hysterectomy, the most frequently performed operation of gynecology clinics, is an effective treatment modality in relieving symptoms and increasing quality of life with relatively lower complication rates. However, its morbidity and complications is agreed to be higher when compared with those of vaginal hysterectomy. Therefore, vaginal approach should always be preferred if possible. When abdominal route is mandatory, an appropriate antibiotic prophylaxis should be used to decrease the rate of febrile morbidity which is the most commonly seen postoperative complication.
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