Objective: Patients with cancer have an increased risk of severe coronavirus disease-2019 (COVID-19) because their immune
systems are suppressed due to cancer treatments or cancer itself. Therefore, patients with cancer are prone to COVID-19 infection. In this study,
we evaluated the anxiety of patients receiving cancer treatment in our oncology department during the COVID-19 pandemic. Material and
Methods: This descriptive cross-sectional study consisted of 220 patients receiving cancer treatment in the medical oncology clinic of our
hospital between 01 and 30 April 2020. Study data were obtained using a questionnaire consisting of 26 questions. The Hospital Anxiety and
Depression Scale was used to determine the patients’ psychological distress. The scale results were compared with the results of Kruskal-Wallis,
Mann-Whitney U, and chi-square tests. Results: We observed that 80 (36.4%) and 40 (18.2%) of the 220 patients studied had risks of depression
and anxiety, respectively. In this study, 46.4% of the patients believed that their illness was being negatively affected by the COVID-19
pandemic, and 45.5% of the patients worried that their treatment would be interrupted during this period. Conclusion: Our results suggest that
patients with cancer need more psychosocial support than do the general population during this pandemic period. These needs should be considered
while planning oncological health services, and appropriate arrangements should be made.
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Aim: This study aimed to evaluate the status of receiving education on rational drug use, the criteria in medical drug selection, and the level of knowledge of dentists working in a dentistry faculty in Turkey. Materials and Methods: This was a descriptive study based on a questionnaire. One hundred seventeen (74%) dentists volunteered to participate in the study. The questionnaire consisted of 20 questions investigating sociodemographic features and rational drug use. Results: The mean age of the dentists was 30.8±7.2 years, and 62.4% of them were men. The mean period of professional experience was 8.9±7.1 years. The most frequently used resources of references while prescribing medicine were Vademecum (medical drug guide) (61.5%), the internet (59.0%), and colleagues (49.6%).According to the responses of the dentists about their level of knowledge of drugs, the most frequently reported condition described as ‘good’ was drug indications (43.6%). The dentists had a moderate level of information about posology and administration route (48.7%), pharmacologic features (48.7%) and contraindications (46.2%). The number of dentists who stated that they considered the cost while prescribing was low (always, 6%, and frequently, 15.4%). 23.9% of the dentists received education for rational drug use. Conclusion: It was determined that dentists did not receive adequate and effective education on rational use of drugs. Regular and continuous education before and after graduation is a necessity for both dentists and their patients.
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Objective: Steroid therapy is the gold standard in treating sudden sensorineural hearing loss (SSNHL). This study aimed to compare the results of the systemic and intratympanic administration of steroids used to treat patients with SSNHL. Methods: A retrospective analysis was performed with 90 patients treated for SSNHL in our clinic between 2014 and 2017. Intratympanic steroid (ITS) was administered to 44 patients and systemic administration (intravenous or oral) to 46. Pure-tone average (PTA) values were recorded before treatment and at the first and third months post-treatment. Hearing improvement was evaluated according to the Furahashi criteria. Results: The pre-treatment PTA values were 68.9 ± 25.9 dB in the systemic steroidtreated group and 79.0 ± 22.6 dB in the intratympanic steroid-treated group, with no statistically significant difference determined (P = .07). After 1 month of treatment, the PTA median value was 6.0 (from −23.0 to −65.0) dB in the systemic group; and the median was 7.5 dB (from −13.0 to −84.0) in the intratympanic group. No statistically significant difference was determined between the groups in terms of regression in pure-tone median values after treatment (P = .90). According to the Furahashi criteria, in the evaluations between the 2 groups, those with complete improvement and significant improvement were compared together, and those with mild improvement and those without improvement were compared separately. There was no statistically significant difference in the distribution with respect to healing, between the groups (P = .692). Conclusion: Although steroids––which are the only treatment with proven efficacy in sudden idiopathic hearing loss––are effective in the improvement of hearing, the methods of administration showed no differences in terms of effectiveness.
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Amaç: Hastane çalışanlarında göz kuruluğu şikayetlerinin sıklığının belirlenmesi, bireysel ve işle ilişkili risk faktörlerinin değerlendirilmesiamaçlandı.Gereç ve Yöntem: Tanımlayıcı kesitsel tipte planlanan çalışmanın evrenini üniversite hastanesi çalışanları oluşturmaktaydı. Çalışmahakkında bilgilendirilmenin ardından katılmaya gönüllü olanlara, araştırmacılar tarafından geliştirilen 15 soruluk anket ve oküler yüzeyhastalık indeksi anketi uygulandı. Veriler SPSS paket programında değerlendirildi ve analizlerde p<0,05 değeri istatistiksel anlamlılıkdüzeyi kabul edildi.Bulgular: Araştırmaya alınan 173 çalışanın yaş ortalaması 37,9±8,1 yıldı. Bunların % 64,2’si kadın ve %69,9’u üniversite mezunu idi.Katılımcıların % 26,6’sını masa başında çalışanlar ve %37,0’sini yardımcı sağlık personeli oluşturmaktaydı. Çalışanların günlük iş nedeniyleekran kullanım süresi ortalama 4,4±3,0 saat iken toplam ekran kullanım süreleri 6,7±4,2 saatti. Ortalama oküler yüzey hastalıkindeksi skoru 28,9±21,9 olarak belirlendi.Katılımcıların 90’ında (%52,0) göz kuruluğu şikayeti vardı. Şikayeti olanların yaş ortalaması 37,2±8,0 yıldı, %75,6’sı kadındı. Meslekdağılımları incelendiğinde doktorların %71,4’ünde, laborantların %69,2’sinde ve masa başı çalışanlarının %56,5’inde göz kuruluğu şikayetlerivardı. Şikayeti olanların %82,2’sinde şikayetlerin günün geç saatlerinde ortaya çıktığı, %14,4’ünün kontakt lens kullandığı belirlendi.Göz kuruluğu şikayeti kadınlarda, masabaşı çalışanlarında, tedavi hizmeti sunanlarda ve laborantlarda istatistiksel anlamlı düzeydeyüksekti (p<0,05). Hastane çalışanlarının %41,1’inde oküler yüzey hastalık indeksi skoruna göre şiddetli düzeyde göz kuruluğusemptomları vardı. Çalışanların oküler yüzey hastalık indeksi skoru ile iş gereği ekran kullanım süresi ve toplam ekran kullanım süresiarasında pozitif yönde, orta şiddette anlamlı doğrusal ilişki vardı (sırasıyla r: 0,33, p:0,000 ve r: 0,34, p: 0,000).Sonuç: Hastane çalışanlarında önemli düzeyde kuru göz semptomlarının olduğu ve bu durumun özellikle çalışma koşulları ve ortam faktörlerindenkaynaklandığı düşünülmektedir.
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Aim: We aimed to determine whether Neutrophil-to-Lymphocyte Ratio (NLR), Monocyte-to-Lymphocyte Ratio (MLR), Platelet-to-Lymphocyte Ratio (PLR), D-dimer, and troponin values were correlated with the simplified Pulmonary Embolism Severity Index (sPESI) in patients diagnosed as having Pulmonary Embolism (PE) in the emergency room.Material and Methods: Forty-three patients diagnosed as having PE in the emergency department were divided into low and high-risk groups according to the sPESI. We investigated whether NLR, MLR, and PLR, d-dimer, troponin-I, and Pulmonary Artery Pressure (PAP) had any effect in determining the severity of PE. Also, patients were divided into groups as those with PAP ≤20 or >20 mm Hg, Systolic Blood Pressure (SBP) ≤100 or >100 mm Hg, and those receiving or not receiving thrombolytic treatment, and compared.Results: There was a statistically significant difference between patients with low sPESI (n=10) and those with high sPESI (n=33) in terms of age (p=0.001), pulse (p=0.016), oxygen saturation (p=0.039), troponin-I (p=0.029) and PAP (p=0.032), but there was no difference between the groups in terms of NLR (p=0.796), MLR (p=0.656), PLR (p=0.863), and d-dimer (p=0.343). There was a statistically significant difference between patients who did (n=6) and did not (n=37) receive thrombolytic treatment in terms of troponin-I (p=0.012), but there was no difference between the groups in terms of NLR (p=0.861), MLR (p=0.335), and PLR (p=0.277).Conclusion: NLR, MLR, PLR and d-dimer levels were found not to be effective in determining the severity of PE. Troponin-I was associated with sPESI and was considered as an effective marker in determining the thrombolytic treatment.
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INTRODUCTION: In this study, the effects of changes in coagulation tests on survival and distant organmetastasis in lung cancer patients were investigated.METHODS: We retrospectively evaluated the data of patients who were diagnosed with primary lung cancer byour radiation oncology clinic. The relationship between age, sex, histopathological diagnosis, metastasis status andcoagulation test values and lifespan were analyzed.RESULTS: A total of 342 patients were included in the study. 18,4% of the patients had small cell lung cancer(SCLC), and 81,6% had non-small cell lung cancer (NSCLC). Adenocarcinoma (45.0%) was the most commonhistopathological subtype in patients with NSCLC. When distant organ metastasis rates were handled for allpatients, while there weren’t distant organ metastasis in 44.4% of patients, distant organ metastasis was found outin 55.6% of the patients. 65.1% of patients with SCLC and 53.4% of patients with SCLC were in advanced stageswith distant organ metastasis. 18.4% of the patients had brain metastasis, and 81.6% had no brain metastasis. Therewas no statistically significant effect of APTT, PT, INR, % PT which are among the coagulation tests, andfibrinogen values on brain metastasis status and survival (p> 0.05). However, in patients with brain metastases,increase in the ratio close to statistical significance the INR and% PT values was found (p = 0.068, p = 0.059,respectively) when compared to the non-men.DISCUSSION AND CONCLUSION: In the case of lung cancer, an increase in the frequency of brain metastasismay be associated with the hypothesis that prolongation of the coagulation test and deterioration of the blood-brainbarrier, but there is a need for extensive studies with more patients.
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Sigara bağımlılığının erken tanınması ve tedavisinin başlanması maliyet-etkinliği en yüksek korunmayöntemlerinden biri olarak kabul edilmektedir. Çalışmanın amacı üniversite öğrencilerde nikotin bağımlılıkdüzeylerinin ve ilişkili bazı özelliklerinin belirlenmesidir. Bu tanımlayıcı çalışmanın evrenini bir kamuüniversitesinde öğrenim gören 30147 öğrenci oluşturmaktadır. Örneklem hesaplamasında en az 453 kişiyeulaşılması gerektiği belirlenmiştir. Çalışmaya düzenli sigara içen gönüllü öğrenciler kabul edilmiştir. Katılımcılaraaraştırmacılar tarafından geliştirilen 17 soruluk bir anket formu ve Fagerström Nikotin Bağımlılığı Ölçeğiuygulanmıştır. Anket verilerinin istatistiksel analizlerinde SPSS programı kullanılmıştır. Tanımlayıcı istatistiklerve önemlilik testleri yapılarak, tüm testler için istatistiksel anlamlılık düzeyi p<0,05 olarak kabul edilmiştir.Katılımcıların yaş ortalaması 21,0±2,9 yıldır ve %58,2’si kadındır. Günde 15 (10-20) dal sigara içmektedirlerve %54,3’ünün babası ve %62,3’ünün yakın arkadaşı sigara içicisidir. Sigarayı bırakmak isteyenlerin sıklığı%19,5’dir. En az bir kez sigarayı bırakmayı deneyenlerin sıklığı %52,8 olup, 2 (1-3) kez sigara bırakma denemesiyapmışlardır. Nikotin bağımlılık testine göre %31,4’ü orta ve %13,4’ü ise yüksek düzeyde bağımlıdır. Yüksekbağımlılarda babanın ve yakın arkadaşının sigara içiciliği daha yüksektir (p<0,05). Yüksek bağımlıların başarısızsigara bırakma denemelerinin daha çok (3[2-3] kez) olduğu belirlenmiştir (p:0,01). Sonuç olarak bağımlılıkdüzeyi artmadan ve sağlık sorunları ortaya çıkmadan, üniversiteli gençlerin sigarayı bırakmak konusunda istekve gayretlerini artırmak gereklidir. Gençleri sigara içmeye teşvik eden olumsuz ortamlardan uzaklaştırmak için;aileleri, akranları ve üniversite çevresi tarafından ihtiyaç duyulan desteğin sağlanması önerilmektedir.
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Objective: Anemia is a common public health issue, causing an increase in mortality and morbidity, especially in pregnant women and children. WHO reported the prevalence of anemia in preschool children as47.4%, and incidence of anemia is gradually increasing. Iron deficiency is responsible for approximately50% of cases with anemia. This study aims to determine the prevalence of anemia and the underlyingcauses of anemia in pediatric patients who were admitted to a reference hospital.Method: This cross-sectional study was planned retrospectively and children between 0.5-15 years of agewho were admitted to our hospital for any indication between July 2017-July 2018 were included.Sampling Among these patients with anemia, those with hemoglobin values less than 11 g/dl were included in the study.Results: The incidence of anemia was detected as 8.2% (n=4655). The median age of anemic children wasthree years, and 54.4% of them were male. Anemia was more common among 2-5 year-old-children(50.8%). The prevalence of anemia was higher in boys between ages of 0.5-1 and 2-5 years, while it washigher in girls between ages of 10-12 and 13-15 years with a statistically significant difference. The median hemoglobin value was 10.2 (min-max: 2.8-10.9) g/dl, and MCV was 74.5 (min-max: 46.9-126.8) fl.Conclusion: The incidence of anemia in a reference centre in Black Sea region of Turkey in children between 0.5-15 years of age is 8%. The laboratory parameters were consistent with a probable diagnosis of irondeficiency anemia. The majority of patients (64%) had mild anemia. Collaboration between physicians andparents in the prevention and treatment of anemia is critical in protecting children from anemia, which isthe cause of preventable mental retardation.
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Aim: An increase in the elderly population owing to an extended average life expectancy leads to an increase in the geriatric patientadmissions to the emergency departments (EDs). The aim of this study was to investigate the intensity of geriatric patients amongall admissions to the emergency department and to determine the importance of these patients in hospitalizations from the EDs.Material and Methods: Geriatric patients aged over 65 years were retrospectively evaluated between 1 January 2017and 31December 2018. The patients were divided into two groups by the age: 65–79 (group I) and ≥80 years (group II). The number of daysof hospitalization and mortality in the intensive care units (ICUs) and clinics were examined.Results: Of 386.670 patients aged over 18 years who were admitted to the ED, 17% (n=65.907) were aged ≥65 years. 64.4% of thepatients who were hospitalized in the ICU from the ED were aged ≥65 years. The sex distribution of the patients who were admittedto but died in the ED in both the groups was as follows: Of 62.1% (n=72) in Group II were females, and of 62.1% (n=82) in Group I weremales.Conclusion: In parallel with the increase in the number of geriatric patients in ED, there is a crowding in both clinics and ICUs. Thisarticle highlights the importance of geriatric patients in emergency department admissions and their importance in hospitalizations.Hospitalization and mortality rates increase with age.
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Amaç: Sağlık profesyonellerinin çalışma ortamları, çalışanların sağlığı için riskli alanlardan biridir. Tıpfakültesi öğrencileri, özellikle de intörnler, eğitimleri ve hastanelerdeki klinik uygulamaları sırasında bu riskleremaruz kalmaktadırlar. Bu çalışmada, Tıp Fakültesi’nde öğrenim gören intörnlerin karşılaştıkları bazı meslekirisklerin ve işle ilgili şikayetlerinin belirlenmesi amaçlanmıştır. Gereç ve Yöntemler: Tanımlayıcı tiptekiçalışmaya 2016 yılında bir Tıp Fakültesi Hastanesinde öğrenim gören tüm intörnler dahil edilmiştir. Verileraraştırmacı tarafından geliştirilen anket formu ile toplanmış ve SPSS 22.0 paket programında analiz edilmiştir.Veriler sayı, yüzdelik, ortalama ve ortanca ile ifade edilmiştir. Bulgular: İntörnlerin %87'sinin çalışma süresihaftalık 45 saati aşmaktadır. Çalışma ortamı ve koşullarıyla ilişkili olarak uykusuzluk (%84.3), yorgunluk (%79.1),yeterli ve dengeli beslenememe(%76.9), sosyal kısıtlılık (%75.4), boyun ve sırt ağrısı (%57.5) gibi şikayetlerininolduğu belirlenmiştir. İntörnler en sık biyolojik etkenler (%92.5’i) ile karşılaşabileceklerini ifade etmişlerdir.İntörnlerin delici-kesici aletle yaralanması sıklığı %73,9 olup, yaralananların %86’sı yaralanma sırasında eldivenkullandıklarını belirtmişlerdir. Son bir yılda hasta ve/veya hasta yakınları tarafından şiddete uğrama sıklığının%61.9 olduğu tespit edilmiştir. Sonuç: Sağlıklarını tehdit eden ve en sık karşılaşılan risk faktörleri fazla çalışmasüresi ve delici-kesici alet yaralanması olarak belirlenmiştir. Ayrıca şiddet oranındaki yükseklik de dikkat çekicibulunmuştur. Tıp fakültesi ve eğitim veren hastanelerin yöneticilerinin, risk faktörlerini azaltılmaya yönelikdüzenlemeler yapması ve intörnlerde de mesleki risk faktörleri açısından farkındalığın arttırılması önerilmektedir.
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