• ÖZ

It is commonly well-known that biofilms are the predominant mode of bacterial growth, reflected in the clinic observations, where approximately 80% of all bacterial infections are related to biofilms. Bacteria in biofilms are well protected against environmental stresses, antibiotics, disinfectants and the host’s immune system and are usually extremely difficult to eradicate. Due to common problems caused by biofilms, alternative anti-biofilm strategies must be developed. Enterococcus strains are able to form complex surface-associated communities (biofilms), which contribute to its resistance and persistence in both host and non-host environments, and are especially important in food processing and clinical environments. Enterococcus biofilms showed increased antimicrobial resistance to the most of antibiotics as compared to the planktonic bacteria, which make them difficult to combat. There is an increasing evidence that biofilms are often associated with infectious diseases. Novel anti-biofilm strategies must be designed to include natural bio products instead of common antibiotics. Mushrooms are a nutritionally functional foods and a source of pharmaceuticals having functions such as antitumor, immunomodulating, antioxidant, cardiovascular, anti-hypercholesterolemia, antiviral, antibacterial, anti-parasitic, antifungal, detoxification, hepatoprotective, and antidiabetic. In addition, they have a notable activity against biofilms. In this study, the antimicrobial and anti-biofilm activities of some medicinal and edible mushrooms, namely Morchella angusticeps Peck, Ganoderma lucidum (Curtis) P. Karst., Cerioporus squamosus (Huds.) Quél., Trametes versicolor (L.) Lloyd and Lentinula edodes (Berk.) Singer were screened against multi drug resistant Enterococcus strains. As a result, it was observed that these mushrooms have notable potency to develop alternative medicines to struggle infectious diseases and biofilms.

• ÖZ

The purpose of this research was to identify Rustroemia samples from Bolu province (Turkey) on June 22, 2019. The samples were identified based on both conventional and molecular methods (ITS region of the rDNA). By considering the high sequence similarity of the collected samples (Akata 7020) with Rutstroemia elatina (Alb. & Schwein.) Rehm, the relevant specimen was considered to be R. elatina and the morphological data supported this finding. This species was firstly reported from Turkey. The results of the molecular analysis and a short description of the newly reported species along with its colored images associated with macroscopic and microscopic structures were conferred.

• ÖZ

The present study reports macrofungi specimens collected from Şemdinli and Yüksekova districts (Hakkari) between 2014 and 2016. As a result of field and laboratory studies, 197 species were identified. Together with the previously reported six species, 203 species belonging to two division, 48 families and 97 genera were listed from the study area. Among them, 36 species belong to Ascomycota, and 167 to Basidiomycota.

• ÖZ

Mantar zehirlenmeleri, tüm dünyada sık karşılaşılan, türü ve toksinine göre asemptomatik bulgulardan ölümcül organ yetmezliklerine kadar geniş klinik spektrumla seyreden bir sağlık sorunudur. Zehirlenmeye yol açan mantarın toksini çoğunlukla tanımlanamadığından hedef organ sistemi toksisite bulgularına göre sendromik sınıflandırma klinik yönetime fayda sağlayabilir. Diabetes mellitus, koroner arter hastalığı, hipertansiyon ve hiperlipidemi gibi komorbiditeleri bulunan 64 yaşındaki kadın hasta yoğun bakım ünitesine kabul edildi. Yabani mantar yedikten yaklaşık 4 saat sonra diyare, kas krampları, soğuk terleme, bulanık görme, öksürük, nefes almada güçlük şikayetlerinin başladığını iletti. Solunum sistemi muayenesinde takipne, yaygın bilateral ronküs, bronkore ve hışıltılı solunum saptandı. Normotansif ve bradikardikti (kalp hızı 35 atım/dakika). Glasgow Koma skoru 15 olan hastanın anksiyetesi vardı. Pupiller bilateral izokorik, miyotik ve ışık refleksleri azalmıştı. Arteriyel kan gazında pH 7,26, parsiyel karbon dioksit basıncı 34 mmHg, potasyum 5,3 mmol/L, sodyum 130 mmol/L, laktat 5,3 mmol/L, bikarbonat 16 mEq/L, baz fazlalığı -10,3 mmol/L saptandı. Hedef organ sistemi toksisite bulguları ve ortaya çıkış zamanlaması erken başlangıçlı kolinerjik sendromu işaret ediyordu. İntravenöz atropin, sıvı, elektrolit, sodyum bikarbonat destek tedavileri toksisitenin kısa sürede düzelmesini sağladı. Geç sonuçlanan mikolojik inceleme sonuçları, hastanın muskarin içeren Inocybe lacera adlı mantar ile zehirlendiğini gösterdi. Bu olgu sunumu ile klinik yönetimde faydalandığımız sendromik sınıflandırmayı literatürdeki güncel bilgiler ışığında özetlemek istedik