• ÖZ

Objective: This study aimed to investigate the knowledge, attitude and behaviors of people about human papillomavirus (HPV) infection and HPV vaccine. Material and Method: In this cross-sectional study, a detailed questionnaire was completed by participants who were admitted to the outpatient clinics of a secondary care hospital between June 2019 and December 2019 and the knowledge, attitude and behaviors of these participants about HPV infection and HPV vaccine were assessed. Results: A total of 836 participants who were admitted to different outpatient clinics of a secondary care hospital between June 2019 and December 2019 were included in the study. Mean age of the participants was 36.29±9.03 and 86.36% of them were female. While 44.26% of the participants were university graduates 44.98% had a master’s degree. Of the participants, 73.09% (n=611) stated that they had never had gynecological exam. While 73.32% (n=613) of the participants answered the question how HPV is transmitted as “yes, it is sexually transmitted” 67.58% (n=565) knew the relationship between HPV and cervical cancer. Of the participants, 71.05% (n=594) knew that cervical cancer was a disease that could be prevented with HPV vaccine. While 56.57% (n=336) stated that they heard HPV vaccine from their physicians 8.85% knew that HPV vaccine was not in the vaccination program of the Ministry of Health. Of the participants, 43.66% (n=365) stated that they had no intention of having HPV vaccine for themselves, their wife/husband or their children. While 11.48% (n=96) of the patients stated that they would not have the vaccine even if it was covered free of charge by the government 31.57% (n=264) stated that they would have the vaccine if it was provided free of charge by the state. Conclusion: People have insufficient knowledge on that cervical cancer is a disease that can be prevented by HPV vaccine, how HPV virus is transmitted and which measures must be taken. Main reason is that the vaccine is not included in the routine vaccination schedule in our country, that healthcare workers do not sufficiently inform patients about HPV vaccine and infection and that the vaccine is expensive in conditions of our country. Underlying reasons why institutions or workers who provide healthcare insufficiently inform people about HPV vaccine can be questioned in detail.

• ÖZ

Objective: The aim of this study was to examine the maternal and fetal outcomes of patients undergoing peripartumhysterectomy (PH) after vaginal delivery (VD) and cesarean section (C/S).Methods: The files of patients undergoing PH following postpartum hemorrhage (PPH) between January 2005 andNovember 2018 were reviewed retrospectively. Patients undergoing PH were divided into two groups as C/S and VD.Age, parity, gestational weeks, time between delivery and hysterectomy, estimated blood loss, duration of operation,number of blood transfusions, hospitalization time, APGAR scores of the fetus at the 1st and 5th minutes, previous C/Shistories, fetal and maternal mortality, indications for PH, additional surgeries performed during PH, and pre-op and postop complications were recorded retrospectively and the groups were compared.Results: A total of 147 patients who underwent PH for postpartum PPH were identified. Of the patients included in thestudy, 77 underwent PH after VD and 70 underwent PH after C/S. There was no statistically significant difference betweenthe groups in terms of age, parity, time between delivery and hysterectomy, estimated blood loss, number of bloodtransfusions, hospitalisation time, and maternal mortality rates. The gestational weeks of the patients in the VD groupwere higher than that of the patients in the C/S group (P = 0.003). Mean duration of operation of the C/S group was longerthan that of the VD group (P ˂ 0.001). APGAR scores of the fetus at the 1st and 5th minutes were higher in the VD groupcompared to the C/S group (P ˂0.001, P ˂0.001, respectively). The most common indication for PH was uterine atony inthe VD group (n: 54, 70.1%) and uterine rupture in the C/S group (n: 24, 34.2%). Disseminated intravascularcoagulopathy (DIC) was the most common complication in both groups. Conclusion: While fetal mortality and morbidity are higher in patients undergoing hysterectomy after C/S, long-termeffects caused by C/S (previous C/S, placenta accreta, placenta previa) increase PH risk. However, it should also beconsidered that PH risk may increase after VD as well.

• ÖZ

Amaç: Anormal uterin kanama (AUK) şikâyeti olan ve histerektomi planlanan hastalarda ameliyat öncesi yapılan pipelle ile alınanendometrial örnekleme sonuçları ile histerektomi sonrası incelenpatoloji spesimenlerinin sonuçlarını karşılaştırmak ve biyopsinintanıdaki doğruluğunu araştırmaktır.Materyal ve Metot: Bu retrospektif çalışmada, Ocak 2014 –Ocak 2018 tarihleri arasında kliniğimize AUK nedeniyle başvuran,pipelle ile endometrial biyopsisi yapılmış ve sonrasında histerektomisi yapılan hastaların kayıtları araştırıldı. Hastaların demografikverileri kaydedildi, endometrial biyopsilerinin ve histerektomilerinhistopatolojik sonuçları çıkarıldı. Tanısal doğruluk, sensitivite,spesifite, pozitif ve negatif prediktif değerler hesaplandı.Bulgular: Çalışmaya toplam 387 hasta dahil edildi. Hastaların yaşortalaması 46,6±6,2 olarak bulundu. Pipelle endometrial biyopsiile histerektomi materyallerindeki nihai patolojideki sensitivesi enyüksek olan endometrium kanseri (%33,3), spesifitesi en yüksekolan basit atipili hiperplazi (%99,1), pozitif prediktif değeri en yüksek olan basit atipisiz hipeplazi (%42), negatif prediktif değeri enyüksek olan ise kompleks atipili hiperplazi (%97,6) ve tanısal doğruluğu en yüksek olan kompleks atipisiz hiperplazi (%95,8) olarakbulunmuştur.Sonuç: Endometrial biyopsi, endometrial patolojinin tanısındaduyarlı ve spesifik bir testtir ancak yine de fokal lezyonlarda ektanı yöntemlerine gerek duyulabilir. Bu çalışmada tanısal doğrulukkompleks atipisiz hiperplazide ve endometrium kanserinde dahayüksek bulunmuştur.