Abdullah SAYINER,
M. Sezai TAŞBAKAN ,
BEGÜM ERGAN ,
Oğuz KILINÇ ,
AYÇA ARZU SAYINER ,
Rüçhan SERTÖZ , Selin OZUYGUR,
Selin ERCAN ,
Yusuf SAVRAN ,
PERVİN KORKMAZ EKREN ,
Özen Kaçmaz BAŞOĞLU ,
Mustafa OZHAN
To evaluate the clinical features and outcomes of patients who were admitted with a diagnosis of coronavirus disease 2019(COVID-19) but who were not confirmed with polymerase chain reaction (PCR) positivity.MATERIAL AND METHODS: This is a retrospective analysis of all patients admitted to two tertiary care centers between March 15 andMay 15, 2020, with a diagnosis of COVID-19. From a common database prepared for COVID-19, we retrieved the relevant data andcompared the clinical findings and outcomes of PCR-positive patients with those of PCR-negative cases who had been diagnosed on thebasis of typical clinical and radiographic findings.RESULTS: A total of 349 patients were included in the analysis, of which 126 (36.1%) were PCR-negative. PCR-negative patients wereyounger (54.6 ± 20.8 vs. 60.8 ± 18.9 years, P = .009) but were similar to PCR-positive patients in terms of demographics, comorbidities,and presenting symptoms. They had higher lymphocyte counts (1519 ± 868 vs. 1331 ± 737/mm3, P = .02) and less frequently presentedwith bilateral radiographic findings (68.3% vs. 79.4%, P = .046) than PCR-positive patients. Besides, they had less severe disease andbetter clinical outcomes regarding admission to the intensive care unit (9.6% vs. 20.6%, P = .023), oxygen therapy (21.4% vs. 43.5%, P< .001), ventilatory support (3.2% vs. 11.2%, P = .03) and length of hospital stay (5.0 ± 5.0 vs. 9.7 ± 5.9 days, P < .001).CONCLUSION: This study confirms that about one-third of the COVID-19 patients are PCR-negative and diagnosed based on clinicaland radiographic findings. These patients have a more favorable clinical course, shorter hospital stays, and are less frequently admittedto the intensive care unit.
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OBJECTIVE: During the COVID-19 pandemic, physicians have been working for long hours, with the fear of contracting the disease and infecting their families. Therefore, there are great concerns about the mental health of physicians. In this research, we aimed to reveal the factors that affect the burnout among physicians working during the pandemic. MATERIAL AND METHODS: This is a cross-sectional study involving physicians working during the pandemic in health institutions that admit COVID-19 patients. A questionnaire form consisting of the “Sociodemographic Data Form” and the “Maslach Burnout Inventory (MBI)” was used. The questionnaire was sent to the contact numbers of physicians via the internet. The target population was reached through the communication groups of the Turkish Thoracic Society and other professional associations, the communication groups of health institutions, and also through personal correspondence. Burnout was evaluated with the scores of each participant from the 3 subscales of Emotional Exhaustion (EE), Depersonalization (DP), and Lack of Accomplishment (LA). RESULTS: Of the 1177 physicians who participated in the survey, 893 answered the survey completely. Females comprised 56.70% (n = 506) of the respondents, and the mean age was 38.63 (±11.65). The residents (41%, n = 366) and specialists (31%, n = 277) made up the majority of the physicians. Eighty-six percent (n = 768) of the physicians had difficulty in obtaining personal protective equipment (PPE). It was determined that 81.7% (n = 730) of the 893 physicians were actively working in pandemic units (outpatient clinics, emergencies, inpatient clinics, intensive care units), and burnout was significantly higher in these physicians (P < .01). After excluding other confounding factors by regression analysis, their Maslach total scores and EE scores were found to be significantly high (P = .001). CONCLUSION: Working in pandemic units and facing difficulty in accessing PPE are identified as the most important risk factors for burnout. Hence, we can say that working with PPE, and with the managers’ discretion and support, the physicians’ burnout can be prevented.
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Background: Nicotine addiction is associated with nicotine absorption from the buccal mucosa, and it is stated that the main factor that determines nicotine absorption is saliva pH. In the literature, the effects of changes in saliva pH values after eating and drinking on smoking desire in smokers were not questioned. Aim: To show the effect of saliva pH changes on smoking desire. The secondary aim was to show the impact of coffee and water drinking on saliva pH and smoking on oral-dental health (oral hygiene and gingival bleeding). Study Design: Case–control study. Methods: A questionnaire was administered that included “Socio demographic Data Form” and smoking history and Fagerström Test for Nicotine Dependence (FTND). Oral and dental examinations were performed with mirror sonds and using oral hygiene standard Silness and Leöe plaque index and DMFT Index (Index of Decayed Missing or Filled Teeth). Untreated saliva samples were taken, and baseline saliva flow rate and pH values were measured. To assess pH changes, saliva pH was remeasured after sugar-free instant coffee and water consumption. Smoking desire was evaluated with the Visual Analog Scale (VAS). Results: In this study, 24 (55.8%) females and 19 (44.2%) males were among the 43 smoking and 39 nonsmoking cases. Smoking was signifi cantly associated with poor oral hygiene (in smokers 4.71 (±1.40), in non-smokers 2.30 (±1.59); P < .01). DMFT index was higher in smok ers than in non-smokers (in smokers 6.45 (±3.69), in non-smokers 3.87 (±2.67); P < .01). Gingival bleeding was more prevalent in smokers (0.68 (±0.76)) than non-smokers (1.20 (±0.90); P = .009). Salivary flow rates were lower in smokers (in smokers 2.56 (±1.34), in non-smokers 3.00 (±1.22), P = .06). In both groups, pH values increased after coffee consumption and decreased after water; in smokers basal: 6.67 (±0.41), pH coffee: 6.93 (±0.36), pH water: 6.85 (±0.33); in non-smokers pH basal: 6.84 (±0.37), pH coffee: 7.02 (±0.37), pH water: 6.97 (±0.31), P < .01. The VAS values of smokers at basal 4.73 (±3.21); P < 0.01, after coffee consumption 4.91 (±3.08); P < .01, and after water 3.15 (±2.72); P < .01. Conclusion: The saliva pH increased after coffee consumption and decreased after drinking water. Besides, VAS values decreased significantly after drinking water. The results suggest that a simple behavior such as drinking water may be used in conjunction with behavioral and cognitive therapies to pursue smoking cessation.
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Objective: The aim of this study is to analyze the acute effect of exercise on the rate of exhaled carbon monoxide (CO) in healty young smokers. Material and Methods: Twenty four male smokers were included in the study. Pulmonary functions of the participants were evaluated by spirometer forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC, peak flow rate (PEF) and forced expiratory flow at 25 to 75% of FVC (FEF 25%-75%). Exercise testing was performed by using bicycle ergometer. Maximal load, maximum oxygen uptake (VO2max), rest and maximal heart rate were recorded. CO levels before and after the test were mesured with portable breath CO monitor. CO levels and changes were assessed and compared on the exercise test day and rest day (without exercise test). Results: 25% of the participants have dyspnea, 20.8% have cough and 50% have sputum complaints. The results of the pulmonary function test and exercise test of young healthy smokers are as follows: % FEV1=89.7±9.9, % FEV1/FVC=87.4±8.2, % PEF=77.4±9.5, mean rest heart rate=94.8±9.8 bpm, mean maximal heart rate=170.3±9.7 bpm and mean VO2max=30.9±6.5 mL/min/kg. There is a statistically significant difference between the first and the second CO values of the participants measured on both days (p<0.001). There is a significant difference between the mean change of CO on the exercise test day and rest day (p<0.001). Conclusion: Our results show that smoking causes respiratory symptoms, impaired cardiopulmonary responses to exercise and increased CO level and exercise increases to the exhaled CO rate in young and healthy male.
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Nur YAPAR,
Eyüp Sabri UÇAN ,
Fırat BAYRAKTAR ,
Necati GÖKMEN , Arzu SAYINER, Ziya KURUÜZÜM,
Başak BAYRAM ,
Sema ALP ÇAVUŞ ,
Oğuz KILINÇ ,
Vildan Avkan- OĞUZ ,
Yusuf SAVRAN ,
Semih KÜÇÜKGÜÇLÜ ,
Murat CELİLOĞLU
In December 2019, in Wuhan, China, scientists observed a sudden and sharp increase in the number of cases of pneumonia and acute respiratory distress syndrome of an unknown origin. By the end of January 2020, the outbreak had spread to Asia, Europe, America, and Australia. In this article, we have outlined the pandemic action plan of our university hospital.
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OBJECTIVE: In this study, we aimed to investigate the effectiveness of a smoking cessation initiative for workers who are smokers in a textile factory located in Denizli, Turkey. MATERIAL AND METHODS: This retrospective cohort was conducted by using the occupational health and safety unit records of 821 workers who are smokers. All participants underwent cognitive behavioral therapy, and in case of need, a suitable pharmacological treatment was initiated. The status of smoking cessation was checked at the end of the third month with a carbon monoxide breath monitor. A chi-square test was performed to make comparisons between categorical variables. Logistic regression analysis (backward) was used to evaluate the factors related to the smoking cessation status. RESULTS: The ratio of participants who gave up smoking was 74.3%, and 63% of them used a pharmaceutical aid to quit smoking. Working in the department of finishing and using a pharmaceutical aid to quit smoking were related to increased success in smoking cessation. CONCLUSION: Outcomes of our study emphasize that workplace-based smoking cessation programs may create a huge impact on smoking cessation among workers. Pharmacological aid and cognitive behavioral therapy have been associated with success in quitting smoking.
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Esin ŞENOL ,
Aykut ÇİLLİ ,
Hakan GÜNEN ,
Alper ŞENER ,
Rıdvan DUMLU , Ayşe ÖDEMİŞ, Ayşe Füsun TOPÇU,
Yeşim YILDIZ ,
Rahmet GÜNER ,
Ayhan ÖZHASENEKLER , Birsen MUTLU, Nurdan KÖKTÜRK,
Nurgül SEVİMLİ ,
Nurcan BAYKAM ,
DERYA YAPAR ,
Selami EKİN ,
Mehmet POLATLI ,
Şebnem Eren GÖK ,
Oğuz KILINÇ ,
Abdullah SAYINER , Ömer KARAŞAHİN,
Çağlar ÇUHADAROĞLU , Ayşe Sesin KOCAGÖZ,
Turhan TOGAN ,
Hüseyin ARPAĞ ,
Hakan KATI , İftihar KÖKSAL,
Firdevs AKSOY , Canan HASANOĞLU
OBJECTIVE: To evaluate the rate of pneumococcal pneumonia (PP) among patients with community-acquired pneumonia (CAP) in Turkey and to investigate and compare features of PP and non-PP CAP patients.MATERIAL AND METHODS: This multicenter, non-interventional, prospective, observational study included adult CAP patients (age ≥ 18 years). Diagnosis of PP was based on the presence of at least 1 positive laboratory test result for Streptococcus pneumoniae (blood culture or sputum culture or urinary antigen test [UAT]) in patients with radiographic findings of pneumonia.RESULTS: Four hundred sixty-five patients were diagnosed with CAP, of whom 59 (12.7%) had PP. The most common comorbidity was chronic obstructive pulmonary disease (30.1%). The mean age, smoking history, presence of chronic neurological disease, and CURB-65 score were significantly higher in PP patients, when compared to non-PP patients. In PP patients, 84.8% were diagnosed based ony on the UAT. The overall rate of PP patients among CAP was calculated as 22.8% considering the UAT sensitivity ratio of 63% (95% confidence interval: 45-81). The rate of intensive care treatment was higher in PP patients (P = .007). While no PP patients were vaccinated for pneumococcus, 3.8% of the non-PP patients were vaccinated (P = .235). Antibiotic use in the preceding 48 hours was higher in the non-PP group than in the PP group (31.8% vs. 11.1%, P = .002). The CURB-65 score and the rate of patients requiring inpatient treatment according to this score were higher in the PP group.CONCLUSION: The facts that PP patients were older and required intensive care treatment more frequently as compared to non-PP patients underline the burden of PP.
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OBJECTIVES: The purpose of this article is to introduce asthma-themed chest diseases elective program applied within the scope of the Dokuz Eylül University School of Medicine. undergraduate medical program. MATERIALS AND METHODS: Asthma-themed chest diseases elective internship program in Year 4 was developed to increase student gains from the elective internship program. During the two-week program, lectures and bedside and outpatient clinics practices were implemented.RESULTS: Students’ pre-education and post-education knowledge scores and OSCE scores were investigated. A minimal increase was observed in post-education score, and no significant difference was determined in the statistical analysis. The students’ post-education clinical performance scores were significantly higher than that of pre-education.CONCLUSION: Asthma-themed chest diseases elective internship program seems to be effective in increasing the clinical performance of the students.
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Kronik akciğer hastalıklarında pnömokokal infeksiyonlar çok önemli bir mortalite ve morbidite sebebidir. Bununla birlikte hastalıkların
tedavisini oldukça zorlaştıran alevlenmeler ve tedavi sırasında kullanılan kortikosteroidler pnömokokal infeksiyon açısından büyük bir
risk taşımakta ve tedaviyi olumsuz etkilemektedir. Pnömokokların kronik akciğer hastalıklarının klinik ve ekonomik yükü üzerindeki
olumsuz etkisini azaltmanın en akılcı yolu riskli popülasyonun aşılanmasıdır. Aşı önerilen grupların iyi tanımlanmış olması, ulusal ve
uluslararası kılavuzlar tarafından önerilmesi ve ülkemizde sağlık otoritelerince aşıların ödeniyor olmasına karşın, Türkiye’de erişkin
kronik akciğer hastalıklarında aşılanma oranları beklenenin oldukça altındadır. Hekimler aşılama konusunda hastalarını yönlendirebilecek
en önemli ve güvenilir kaynak olarak değerlendirildiğinden pnömokok aşılamasını kronik akciğer tanısı alan tüm hastalarda rutin
bir şekilde uygulamak ve günlük pratiğin bir parçası haline getirmek, bu hastalarda görülen pnömokokal infeksiyonların yarattığı klinik
ve ekonomik yükün azaltılmasına büyük katkı sağlayacaktır. Bu derlemede kılavuzlar ve güncel literatürler eşiliğinde, pnömokokal
hastalıkların kronik akciğer hastalıkları üzerine etkileri, kronik akciğer hastalarında pnömokokal hastalıkların riski ve klinik yükü ele
alınarak bu hastalarda pnömoniden korunmanın önemine değinilmiştir. Ülkemizde mevcut olan pnömokok aşıları hakkında genel
bilgiler ve etkinlik verileri yanı sıra, uygulama şekilleri ve aşılara erişim yolları da anlatılmıştır.
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